Changes in quality of life among breast cancer patients three years post-diagnosis

Lü, Wei; Cui, Yong; Chen, Xiaoli; Zheng, Ying; Gu, Kai; Cai, Hui; Wang, Zheng

doi:10.1007/s10549-008-0008-3

Cited by 60 publications

(59 citation statements)

References 56 publications

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“…It has been suggested that traditionally the breast carries less significance in sexuality and body image in Asian cultures than in Western countries, and that attitudes on changes in body image caused by breast cancer treatment depend on race and social background [20]. The results of this study in Japanese women showed that body image at baseline had no significant effect on the FACT-G, a comprehensive QOL scale.…”

Section: Discussionmentioning

confidence: 53%

“…HRQOL was evaluated in 2232 Chinese patients with breast cancer who enrolled in the Shanghai Breast Cancer Survival Study at 6 and 36 months after diagnosis. Overall HRQOL and physical, psychological and social well-being improved over time, while several factors showed a decline with time, including negative feelings, social support, interpersonal relationships, financial situation and living environment, with a particularly marked worsening of interpersonal relationships [20]. The FACT-G questions concerning social well-being examine relationships with family, partner and friends; therefore, the decreased social well-being found in the current study is similar to the changes observed by Lu et al…”

Section: Discussionmentioning

confidence: 96%

“…This finding requires further analysis, since cancer progression generally correlates with poor HRQOL [11,20]. Of the treatment-related factors, intravenous systemic chemotherapy after surgery was the strongest significant predictor for HRQOL.…”

Section: Discussionmentioning

confidence: 98%

“…Physical, emotional and functional well-being significantly improved, but social well-being significantly decreased. Lu et al [20] recently examined changes in HRQOL and factors predicting long-term HRQOL in breast cancer patients using an approach similar to that in the current study. HRQOL was evaluated in 2232 Chinese patients with breast cancer who enrolled in the Shanghai Breast Cancer Survival Study at 6 and 36 months after diagnosis.…”

Section: Discussionmentioning

confidence: 99%

“…This includes clarifying patterns of physical and psychosocial recovery over time, identifying social backgrounds, clinicopathological and treatment-related factors that influence long-term HRQOL, and identifying areas and persons requiring support in the future. Factors with significant effects on long-term HRQOL after treatment of breast cancer include age [18][19][20][21][22][23][24][25], race [9,25], educational status [19][20][21], income [7,8,13], marriage [11,13,21,24,25], recurrence [9,26], disease period [11,20], surgical procedure [7,19,20], chemotherapy [8,10,11,14,20,24], physical activities [27] and culture [25,28]. In our previous longitudinal prospective study, the factors predicting HRQOL at one year after surgery were mood disturbance, poor body image, lower income and positive axillary nodes one month after surgery [17].…”

Section: Introductionmentioning

confidence: 99%

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Associations among baseline variables, treatment-related factors and health-related quality of life 2 years after breast cancer surgery

Taira

Shimozuma

Shiroiwa

et al. 2011

Breast Cancer Res Treat

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Provision of social support and rehabilitation for patients with physical, mental and functional problems after cancer treatment is important for long-term health-related quality of life (HRQOL). Effective use of human and financial healthcare resources requires identification of patients requiring rehabilitation. The objectives of the current study were to clarify the patterns of physical and psychosocial recovery over time, to evaluate the associations among baseline variables, treatment-related factors and HRQOL at 6 months, 1 and 2 years after breast cancer surgery, and to identify the significant factors predicting HRQOL at each point. A multicenter longitudinal study was performed to evaluate physical conditions, anxiety, depression and HRQOL at one month (baseline), 6 months, and 1 and 2 years after surgery in 196 patients (mean age: 53.3 years old) with early breast cancer and no postoperative recurrence. Physical conditions were evaluated using a patient-reported symptom checklist. HRQOL was rated using the Functional Assessment of Cancer Treatment scale-General (FACT-G) and the Breast Cancer subscale (FACT-B). Anxiety and depression were rated using the Hospital Anxiety and Depression Scale (HADS).More than 50% of patients had local problems of "tightness", "arm weakness" and "arm lymphedema", and systemic problems of "reduced energy, fatigue, and general weakness" postoperatively. The HRQOL score significantly improved one year after surgery, and scores for physical, emotional and functional well-being also increased with time, whereas the score for social well-being was highest at baseline and decreased with time. Depression and anxiety significantly improved with time. Concomitant disease, marital status and the presence of a partner, anxiety and depression at baseline, pathological lymph node involvement, and adjuvant intravenous chemotherapy were significant factors predicting FACT-G scores at 6 months and 1 and 2 years after surgery. Depression at baseline was a strong predictor of HRQOL up to 2 years after surgery. These results suggest that physical rehabilitation is required for tightness and lymphedema to improve long-term postoperative physical function. A further study of psychosocial interventions is required to improve depression and social well-being after breast cancer surgery.

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Section: Discussionmentioning

confidence: 53%

Section: Discussionmentioning

confidence: 96%

Section: Discussionmentioning

confidence: 98%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Associations among baseline variables, treatment-related factors and health-related quality of life 2 years after breast cancer surgery

Taira

Shimozuma

Shiroiwa

et al. 2011

Breast Cancer Res Treat

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Cognitive behavioural therapy (group) for schizophrenia

Guaiana

Abbatecola²,

Aali

et al. 2022

Cochrane Database of Systematic Reviews

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Population‐based cancer registries for quality‐of‐life research

Thong

Mols

Stein

et al. 2013

Cancer

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BACKGROUND: With the increasing number and diversity of cancer survivors, studies of survivors' physical, emotional, and social health and well being are of growing importance. Population-based cancer registries, which collect data on incident cases, can play an important role in quality-of-life (QoL) studies. In this review, the authors provide an overview of QoL studies that have used cancer registry data in this emerging area of research. METHODS: Publication databases were searched for relevant peer-reviewed original articles published between 2001 and mid-2011. Inclusion criteria were articles published in English that used cancer registries as the sampling frame and/or that used registry data in analyses with QoL data. All included articles were assessed on the quality of information provided, cancer registry procedures, and study design. RESULTS: In total, 173 articles from 13 countries were reviewed, and a large proportion were from the United States (n 5 72) and Europe (n 5 70). Fourteen different malignancies were studied, and the most frequent were breast cancer. Most studies focused on adult survivors, and only 4 focused on the elderly (aged >70 years). Of the reviewed articles, 110 (64%) provided a good amount of information on the cancer registry. Information less frequently reported included mainly follow-up of vital status and characteristics of respondents/nonrespondents. CONCLUSIONS: QoL studies increasingly use population-based registries, which provide important clinical variables and an excellent sampling frame for identifying subgroups. Until now, most studies have tended to focus on more prevalent cancers, and surprisingly few studies have focused on QoL of elderly survivors, who remain understudied in clinical trials. INTRODUCTIONThe number of cancer survivors worldwide is increasing because of a combination of rising cancer incidence rates and improving 5-year survival rates. Specifically, as the absolute size and proportion of the world population aged >65 years continues to grow, it is likely that the number of individuals being diagnosed with cancer also will continue to rise. In addition, advances in cancer screening, early detection, and treatment strategies have resulted in significant increases in the 5-year survival rate for all cancers combined in most industrialized countries.1 However, despite these advances, cancer treatments often are quite debilitating and may put cancer survivors at risk for late/long-term effects, such as fatigue, cardiomyopathy, or second primary cancers.2 Consequently, the long-term well being of cancer survivors has begun to demand increasing attention.2,3 Clearly, more research is needed to address these issues. However, the identification and recruitment of post-treatment cancer survivors can be a challenge to conducting such studies.One potential solution to the challenges of identification and recruitment of cancer survivors for research purposes is the use of national, state, and regional cancer registries. Cancer registries originally were devel...

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Changes in quality of life among breast cancer patients three years post-diagnosis

Abstract: Our study provides valuable information for developing strategies/interventions for improving the QOL of breast cancer patients.

Cited by 60 publications

References 56 publications

Associations among baseline variables, treatment-related factors and health-related quality of life 2 years after breast cancer surgery

Associations among baseline variables, treatment-related factors and health-related quality of life 2 years after breast cancer surgery

Cognitive behavioural therapy (group) for schizophrenia

Population‐based cancer registries for quality‐of‐life research

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