Changes in retinal thickness are correlated with alterations of electroretinogram in eyes with central retinal artery occlusion

Abstract

Measurement of retinal thickness by OCT can be useful for monitoring the changes following CRAO. The correlation between the retinal thickness, especially inner layer thickness, and the ERG components was determined, suggesting that the PhNR in the acute phase might be a good indicator for predicting the thinning of the damaged retina in the chronic phase.

Thrombolytic therapy in central retinal artery occlusion: cutting edge therapy, standard of care therapy, or impractical therapy?

“…Evaluation of the extracranial carotid system can be performed by ultrasonography, magnetic resonance angiography (MRA), or computed tomography angiography (CTA) [10]. An ECG can identify an underlying cardiac arrhythmia.…”

“…Intravenous fluorescein angiography (IVFA) and optical coherence tomography (OCT) can be useful as confirmatory tests in the setting of an uncertain diagnosis [2, 9,10]. IVFA characteristically shows delayed or restricted retinal arteriole filling [24], whereas OCT displays increased inner retinal layer thickness in the acute phase [10].…”

“…CRAO results in infarction of the inner retina leading to a quantifiable reduction in the thickness of the inner retinal layers [10]. Although spontaneous recovery is possible, it is uncommon and unpredictable [11].…”

A review of central retinal artery occlusion: clinical presentation and management

“…39 Optical coherence tomography may demonstrate an increased inner retinal layer thickness in the acute phase due to the retinal oedema and optic nerve swelling. 40 Assessment of vascular risk Physical examination should be undertaken with a focus on the cardiovascular system to determine potential causes. The radial pulse rate and rhythm are important, as irregularly irregular rhythms suggest atrial fibrillation, which is a risk for embolic phenomena.…”

Optical Coherence Tomography in Retinal Arterial Occlusions: Case Series and Review of the Literature

“…10 Another study demonstrated that decreased inner layer thickness was correlated to the chronicity of CRAO, and the ratio of inner layer thickness to neurosensory retinal thickness correlated to ERG changes in patients with CRAO. 8 Macular thickness profiles have also been evaluated as aids in prognosticating ultimate visual outcomes in CRAO in one study. Mean foveal thickness in CRAO patients was 299 AE 76 microns, and mean total macular volume was 7.90 AE 0.93 mm 3 at initial examination, and declined to 167 AE 30 microns and 4.85 AE 0.68 mm 3 .…”