Changes in sexual behavior and risk of HIV transmission after antiretroviral therapy and prevention interventions in rural Uganda

Abstract

Providing ART, prevention counseling, and partner VCT was associated with reduced sexual risk behavior and estimated risk of HIV transmission among HIV-infected Ugandan adults during the first 6 months of therapy. Integrated ART and prevention programs may reduce HIV transmission in Africa.

The impact of HIV treatment on risk behaviour in developing countries: A systematic review

“…At this stage, 101 articles were excluded for not meeting inclusion criteria, and the full-text versions of 65 articles were pulled for further screening. Of these, 3 articles met the criteria for inclusion in this review as a primary article (Moatti et al, 2003;Bateganya et al, 2005;Bunnell et al, 2006), and 59 were included as background articles (Mussico et al, 1994;Kelly et al, 1998a;Kelly et al, 1998b;Remien et al, 1998;van der Straten, 1998;DeNoon, 1999;Misovich et al, 1999;Colebunders et al, 2000;Erbelding et al, 2000;Miller et al, 2000;Vanable et al, 2000;van der Straten et al, 2000;Wood et al, 2000;Catz et al, 2001;Dukers et al, 2001;Vlahov et al, 2001;Bouhnik et al, 2002;Chen et al, 2002;Crepaz et al, 2002;Demmer, 2002;DiClemente et al, 2002;Hosseinipour et al, 2002;Katz et al, 2002;Laporte, 2002;Nollen et al, 2002;Ostrow et al, 2002;Gray et al, 2003; International Collaboration on HIV Optimism, 2003;Rietmeijer et al, 2003;Rothenberg et al, 2003;Stephenson et al, 2003;Xiridou et al, 2003;Boily et al, 2004;Crepaz et al, 2004;Fang et al, 2004;…”

“…Table I presents a description of the three primary articles included in this review. All three were conducted in Africa Á one in Côte d'Ivoire (Moatti et al, 2003) and two in Uganda (Bateganya et al, 2005;Bunnell et al, 2006) Á with HIV-positive adults. Two were cross-sectional studies comparing patients who had received ART to those who had not (Moatti et al, 2003;Bateganya et al, 2005); one was a before/after study following a cohort of Participants received weekly home-based ART delivery and monitoring by lay field officers and referral as needed for free medical and psychological care at the study clinic.…”

“…Individual, couple, and clinic-level data were all used as the unit of analysis. patients initiating ART and examining behavioural outcomes six months later (Bunnell et al, 2006). The overall rigor of these studies was low (Table II).…”

“…The two cross-sectional studies received a rigor score of 1 (out of a possible 8), receiving credit only for having treatment and comparison groups. Bunnell et al (2006) received the highest rigor score of 3 for their before/after study. This study presented the only available longitudinal data; however, the lack of a control group limited the rigor of the study.…”

Disclosure, Knowledge of Partner Status, and Condom Use Among HIV-Positive Patients Attending Clinical Care in Tanzania, Kenya, and Namibia

“…However, the high rates of disclosure and condom use observed in this analysis are consistent with other studies conducted among PLHIV who knew their HIV status and were attending clinical care. [51][52][53] All participants in this sample were PLHIV attending clinical care in a country with a …”