Changes in tear film osmolarity after 25G+ PPV

Abstract

Background The aim of our study was to assess changes of tear film osmolarity after micro-incision 25G+ pars plana vitrectomy (PPV) in a prospective study. Methods The group consisted of 21 patients (17 women, 4 men) with an average age of 70,52 years [48; 85]. All patients underwent 25G + PPV surgery due to a disorder of the vitreomacular interface (macular hole or epimacular membrane). Only patients who did not use artificial tears before the surgery and who had not been diagnosed with dry eye syndrome at ours or another institution were included in the study. Except cataract surgery, all ocular surface diseases, intraocular diseases, trauma or surgery were exclusion criterias. Tear film osmolarity was measured in both eyes in every patient before surgery, 10 days after surgery and 30 days after surgery. A paired test was used for statistical evaluation. Results No statistically significant change in osmolarity was found in the operated eyes (p > 0.05). No statistically significant changes in time (p > 0.05) were found when both eyes were compared. There were no postoperative complications or failure to observe the study protocol. Conclusion Micro-incision 25G + PPV does not affect the osmolarity of the tear film.

Dry eye parameters measured with an ocular surface analyzer in eyes after vitrectomy for vitreomacular interface disorders

“…[ 17 ] Some authors suggest that there is no influence of small gauge vitrectomy on tear film stability. [ 18 ] Another study suggests that 3 months after vitrectomy, the tear break up was different between eyes with and without sutured sclerotomies. No differences were observed in the Schirmer test and corneal surface staining.…”

Ocular surface changes following vitreoretinal procedures

“…[ 41 ] Němčanský et al . [ 42 ] measured tear film osmolarity 10 and 30 days after a 25-gauge PPV. Tear osmolarity did not change significantly after surgery.…”

Ocular surface morbidity related to vitreoretinal interventions

“…The sutureless microincision vitrectomy system (MIVS), which includes the parsplana vitrectomy ports (of 23G, 25G, and 27G) small-gauge systems, results in lesser alteration of tear dynamics in the postoperative period. [ 25 26 27 28 ] Noncontact retinal viewing systems such as the binocular indirect ophthalmic microscope (BIOM) being increasingly used in modern day vitreoretinal procedures help to mitigate the damage to the corneal epithelium. [ 29 ] Optimal preoperative ocular surface stabilization with use of lubricant therapy and anti-inflammatory therapy, bandage contact lens placement at the end of the surgical procedure, and avoiding long duration of surgery can help in better ocular surface comfort in these eyes.…”