Soybean (Glycine max L. Merrill), indigenous to East Asia, has assumed a pivotal role as a global substantial crop, substantially contributing to food security, a wide spectrum of product lines and rigorous scientific exploration. This unassuming legume, bearing the scientific nomenclature Glycine max L. Merrill, has transcended its East Asian origins to become a cornerstone in supplying 25% of the world's edible oil and approximately two-thirds of the global livestock protein concentrate. The significance of soybeans extends beyond their utility in direct human consumption; they serve as an indispensable component in crop rotation, thereby fostering soil health and averting erosion. This comprehensive review embarks on a profound exploration of soybeans, encompassing their historical significance, botanical attributes, geographical distribution, climatic influence and reproductive biology. Furthermore, it provides a detailed account of advancements in genetic enhancement and biotechnological applications within soybean breeding, emphasizing the importance of transgenic soybean production. Disease resistance efforts, including the identification of resistance loci, markers and mutations, are thoroughly discussed, with a specific focus on the improvement of Indian soybean varieties.