Changes in the Brain Activity and Visual Performance of Patients with Strabismus and Amblyopia after a Compete Cycle of Light Therapy

Ibrahimi, Danjela; Mendiola-Santibáñez, Jorge D.; Cruz-Martinez, Enoe; Gómez-Espinosa, Alfonso; Torres‐Pacheco, Irineo

doi:10.3390/brainsci11050657

Cited by 9 publications

(28 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Also, it has been shown that DAN FC changes after acute stress exposure 41 and in sleep problems 42 . In agreement with other studies 21 , the visual cortex seems to increase its FC with red light stimulation, compared with green and blue lights.…”

Section: Discussionsupporting

confidence: 93%

“…In an auditory “2-back” working memory task increased brain activity was found using functional magnetic resonance imaging (fMRI) in the middle frontal gyrus and the supramarginal gyrus with blue light (470 nm), compared with green light (550 nm) 20 . In the visual system, one study found increased activation in posterior and occipital regions using red-light stimulation in esotropia and blue light in exotropia 21 . Interestingly, other authors found that melatonin suppression by blue (470 nm) and amber (590 nm) light exposure is hemispherically dependent in the retina, observing more melatonin suppression in the nasal hemifield 22 .…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Functional connectivity of brain networks with three monochromatic wavelengths: a pilot study using resting-state functional magnetic resonance imaging

Argilés

Sunyer-Grau

Arteche-Fernandez

et al. 2022

Sci Rep

View full text Add to dashboard Cite

Exposure to certain monochromatic wavelengths can affect non-visual brain regions. Growing research indicates that exposure to light can have a positive impact on health-related problems such as spring asthenia, circadian rhythm disruption, and even bipolar disorders and Alzheimer’s. However, the extent and location of changes in brain areas caused by exposure to monochromatic light remain largely unknown. This pilot study (N = 7) using resting-state functional magnetic resonance shows light-dependent functional connectivity patterns on brain networks. We demonstrated that 1 min of blue, green, or red light exposure modifies the functional connectivity (FC) of a broad range of visual and non-visual brain regions. Largely, we observed: (i) a global decrease in FC in all the networks but the salience network after blue light exposure, (ii) a global increase in FC after green light exposure, particularly noticeable in the left hemisphere, and (iii) a decrease in FC on attentional networks coupled with a FC increase in the default mode network after red light exposure. Each one of the FC patterns appears to be best arranged to perform better on tasks associated with specific cognitive domains. Results can be relevant for future research on the impact of light stimulation on brain function and in a variety of health disciplines.

show abstract

Section: Discussionsupporting

confidence: 93%

Section: Introductionmentioning

confidence: 99%

Functional connectivity of brain networks with three monochromatic wavelengths: a pilot study using resting-state functional magnetic resonance imaging

Argilés

Sunyer-Grau

Arteche-Fernandez

et al. 2022

Sci Rep

View full text Add to dashboard Cite

show abstract

“… 37 Lower alpha-wave activity and abnormal distribution of theta-waves in the frontal lobes are found in strabismus and amblyopia, which is related with neurodevelopmental disorders. 38 However, a few studies have explored the function of the advanced cortex in the task-state of 3D perception evoked by DRDS. Our study showed the cortical activity of the theta-waves significantly changed in the frontal lobe of healthy adults when processing binocular disparity.…”

Section: Discussionmentioning

confidence: 99%

Electroencephalography Study of Frontal Lobe Evoked by Dynamic Random-Dot Stereogram

Liu

Shen

Sun

2022

Invest. Ophthalmol. Vis. Sci.

View full text Add to dashboard Cite

Purpose The purpose of this study was to investigate the cortical electrical activity and electroencephalography (EEG) features of the frontal lobe evoked by dynamic random dot stereogram (DRDS) and to probe the functional connectivity (FC) between the frontal lobe and occipital lobe when processing 3D perception based on the binocular disparity. Methods The EEG experiment involved 14 healthy adults with normal stereopsis (<60″) and normal corrected visual acuity (20/20). The Neuroscan system and 32-channel EEG cap were used to record EEG signals based on the DRDS stimuli. The maximum energies of 3 frequency bands (theta-/alpha- /beta-wave) from 13 interesting channels (FP1, FP2, F7, F3, FZ, F4, F8, FC3, FCZ, FC4, O1, OZ, and O2) located in the frontal and occipital lobes were calculated and analyzed. The FC between any two electrodes from the frontal and occipital lobes was calculated based on the Phase lag index (PLI). Results The maximum powers of theta- and alpha-waves in most channels of the frontal and occipital lobes were significantly increased ( P < 0.05) when the depth perception was evoked by DRDS above the threshold, compared with that without stereo vision. The changes in the maximum powers of both theta- and alpha-waves were significantly different among the 13 electrodes ( P = 0.0004 and 0.0015, respectively). Tukey's multiple comparisons showed that the changes in the maximum powers of theta-wave were significantly different in F8 vs. O1, F8 vs. OZ, and F4 vs. O1 ( P = 0.0186, 0.0444, and 0.0412, respectively). Moreover, the changes in the maximum powers of alpha-waves were significantly different in FP1 vs. O1 ( P = 0.0182). The FCs of theta-waves between the frontal channels and the occipital channels were significantly enhanced when processing the depth perception, compared with those without stereopsis. There was no significant change in the FCs of the alpha-waves when having 3D perception except for FC between F8 and O1 and FC between F8 and OZ. Conclusions The cortical electrical activity in the frontal lobe and the functional connectivity between the frontal lobe and the occipital lobe increase when participating in the processing binocular disparity and obtaining 3D perception. Theta-waves in the frontal lobe may be crucial in the stereo vision.

show abstract

“…14 Red light enhances cell membrane capacitance buildup of electrical charge before discharge that enhance the nerve cell charge to break through synaptic resistance to decrease amblyopia. 15 We conducted this study to evaluate the effectiveness of this therapy at our set up, as this area in amblyopia therapy is still void in Pakistani literature.…”

Section: Introductionmentioning

confidence: 99%

Effectiveness of syntonic phototherapy in amblyopia in terms of improved visual acuity and contrast sensitivity

Abbas

Younus

Bukhari³

et al. 2022

pak J Ophthalmol

View full text Add to dashboard Cite

Purpose: To compare visual acuity and contrast sensitivity in different types of amblyopia and to see the effect of syntonic therapy on amblyopia in terms of visual acuity and contrast sensitivity. Study Design: A Quasi Experimental study Place and Duration of Study: A Qusai Experimental study was carried out from August 2021 to November 2021 at Madina Teaching Hospital Faisalabad. Methods: A total of 30 patients of either gender and age from 8 to 18 years were included. There were 15 patients with anisometropic amblyopia and 15 with strabismic amblyopia. The patients were recruited through non-probability purposive sampling technique. All the patients underwent assessment of visual acuity with Log MAR chart and contrast sensitivity with Pelli-Robsonchart. Syntonic phototherapy with red filter glasses was prescribed for 4 weeks. After 4 weeks, patients returned and underwent post-therapy assessment of visual acuity and contrast sensitivity. Paired sample t test and Independent sample t test was used with the help of IBM SPSS-23 to get a statistical result. Results: Syntonic phototherapy showed significant improvement in mean visual acuity of 0.223 (p=0.00) and contrast sensitivity of -0.200 (p=0.00) in amblyopia. Anisometropic amblyopia showed better improvement in visual acuity (p=0.016) and contrast sensitivity (p=0.035) by syntonic phototherapy as compared to patients with strabismic amblyopia. Conclusion: Significant improvement was seen in visual acuity and contrast sensitivity in patients with amblyopia after syntonic phototherapy. Anisometropic amblyopia showed better improvement as compared to strabismic amblyopia, in terms of visual acuity and contrast sensitivity.

show abstract

Changes in the Brain Activity and Visual Performance of Patients with Strabismus and Amblyopia after a Compete Cycle of Light Therapy

Cited by 9 publications

References 37 publications

Functional connectivity of brain networks with three monochromatic wavelengths: a pilot study using resting-state functional magnetic resonance imaging

Functional connectivity of brain networks with three monochromatic wavelengths: a pilot study using resting-state functional magnetic resonance imaging

Electroencephalography Study of Frontal Lobe Evoked by Dynamic Random-Dot Stereogram

Effectiveness of syntonic phototherapy in amblyopia in terms of improved visual acuity and contrast sensitivity

Contact Info

Product

Resources

About