Changes in the Content of Phenolic Compounds and Biological Activity in Traditional Mexican Herbal Infusions with Different Drying Methods

Jiménez-García, Sandra Neli; Vazquez-Cruz, Moises Alejandro; Ramírez-Gómez, Xóchitl Sofía; Beltrán-Campos, Vicente; Contreras-Medina, Luis Miguel; García‐Trejo, Juan Fernando; Feregrino-Pérez, Ana A.

doi:10.3390/molecules25071601

Cited by 15 publications

(23 citation statements)

References 39 publications

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“…In our study, it was found that extracts of hyssop, peppermint, and anise hyssop showed the maximum α-amylase and α-glucosidase inhibitory activities. The effects of extracts from the plants of the Lamiaceae family have also been confirmed in previously published studies [32][33][34][35][36]. The antihyperglycemic effect of their extracts is associated primarily with the presence of flavonoids, hydroxycinnamic acids, as well as diterpenes (forskolin and marrubiin), and triterpenes (ursolic and oleanolic acids) [2].…”

Section: Discussionsupporting

confidence: 57%

Effect of salicylic acid on phenolic compounds, antioxidant and antihyperglycemic activity of Lamiaceae plants grown in a temperate climate

Skrypnik¹,

Golovin²,

Savina³

2022

Front. Biosci. (Elite Ed)

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Background:The Lamiaceae family, one of the most important herbaceous and shrub plant families, includes a wide variety of plants with biological and medicinal uses. This study aimed to conduct a comparative analysis of phenolic compounds content and biological activity of extracts from eight species of Lamiaceae plants, cultivated in a temperate climate, and to study the effect of the foliar salicylic acid application on these parameters. Methods: Lamiaceae plants (Lavandula angustifolia, Salvia officinalis, Hyssopus officinalis, Agastache foeniculum, Thymus serpyllum, Mentha × piperita, Origanum vulgare, Monarda didyma) cultivated on field experimental sites. Plants were sprayed with salicylic acid at a concentration of 1 mM. The untreated with salicylic acid plants were used as control. Results:The highest contents of hydroxycinnamic acids and flavonoids in control plants were observed in the Agastache foeniculum (6.4 ± 0.6 mg g −1 and 6.5 ± 0.4 mg g −1 respectively). The highest content of phenolic compounds was found in Monarda didyma (13.8 ± 0.7 mg g −1 ). Among the control plants, Agastache foeniculum, Hyssopus officinalis, and Mentha × piperita were characterized by the highest antioxidant activity. All the studied extracts had the ability to inhibit α-amylase and α-glucosidase. Significant positive correlations were revealed between the antioxidant activity and the contents of hydroxycinnamic acids, total phenolic compounds, and flavonoids. A high degree of correlation was found between the α-amylase inhibitory activity and the content of hydroxycinnamic acids (r = 0.72, p ≤ 0.05), as well as between the α-glucosidase inhibitory activity and the content of flavonoids (r = 0.83, p ≤ 0.05) and hydroxycinnamic acids (r = 0.81, p ≤ 0.05). The foliar treatment with salicylic acid led to an increase in the contents of hydroxycinnamic acids (in 6 species), flavonoids (in 2 species), total phenolic compounds (in 7 species), antioxidant activity (in 5 species), as well as in αamylase (in 4 species) and α-glucosidase (in 5 species) inhibitory activity compared to the control plants. Lavandula angustifolia was the most susceptible to foliar treatment with salicylic acid. In this plant species, a significant increase in all studied biochemical parameters was noted. Conclusions: The results obtained on the stimulating effects of salicylic acid can be used to increase the nutritional and pharmacological value of plants of the Lamiaceae family cultivated in temperate climates.

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Section: Discussionsupporting

confidence: 57%

Effect of salicylic acid on phenolic compounds, antioxidant and antihyperglycemic activity of Lamiaceae plants grown in a temperate climate

Skrypnik¹,

Golovin²,

Savina³

2022

Front. Biosci. (Elite Ed)

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“…The FD samples were characterized by a higher amount of flavonoid glycosides and cannabinoids, which are mainly in the acid form, while the oven-dried samples had a major relative content of the corresponding flavonoids aglycones. As demonstrated by Jimenez-Garcia et al [ 37 ], freeze-drying seems to be a better drying method to preserve flavonoid compounds, especially in the form of glycosides, considering that they may lose the sugar and degrade to the corresponding aglycone if exposed to high temperatures (65 °C) for a prolonged length of time. The same susceptibility is reported for cannabinoids in the acid form, although the degradation normally occurs at a higher temperature than 65 °C.…”

Section: Resultsmentioning

confidence: 99%

Characterization and Biological Activity of Fiber-Type Cannabis sativa L. Aerial Parts at Different Growth Stages

Mastellone

Marengo

Sgorbini

et al. 2022

Plants

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Currently, there is a renewed interest in cannabis-related products in different fields because of the rich phytocomplex of this plant, together with its fiber and agricultural features. In this context, the current study aims to chemically characterize different samples of fiber-type Cannabis sativa L. grown in Italy as a potential health promoting source. An ultrasound-assisted solid-liquid extraction (UA-SLE) method was first developed and optimized to obtain a fingerprinting of the investigated phytocomplex. Analyses were carried out through an ultra high performance liquid chromatography equipped with a photodiode array detector in series with triple quadrupole system with an electrospray ionization (ESI) interface (UHPLC-UV-ESI-MS/MS) and showed that the phytocomplex mainly includes flavonoids and non-psychotomimetic cannabinoids. The method was then applied to characterize and compare 24 samples of fiber-type Cannabis sativa L. aerial parts (mainly stems and leaves), which differed for the growth stages (from mid-vegetative to early flowering), growth land plots, and methods of drying (forced-draft oven or freeze-drying). The quali-quantitative analysis showed that a freeze-drying method seems to better preserve the chemical composition of the samples, while the location of the land plot and the growth stage of the plant (which did not comprise inflorescences) had minor influences on the chemical pattern. These results were also supported by spectrophotometric in-vitro assays (scavenging of 2,2-diphenyl-1-picrylhydrazyl (DPPH•) and 2,2′-azinobis-3-ethyl-benzthiazoline-6-sulphonate (ABTS+•) radicals and inhibitory activity against tyrosinase and elastase enzymes) to investigate the potential biological activity of these samples and the contribution of non-psychotomimetic cannabinoids.

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“…In turn, the freeze-drying process yielded the highest levels of potentially bioavailable p -hydroxybenzoic acid and sinapic acid. Similarly, in studies on other herbs where three drying methods (conventional, microwave, and freeze-drying) were used, the best extraction results were observed in the case of microwave drying and freeze-drying of melissa and thyme, respectively [ 22 ]. Importantly, these results only apply to “chemical extracts” [ 22 ].…”

Section: Discussionmentioning

confidence: 99%

“…Similarly, in studies on other herbs where three drying methods (conventional, microwave, and freeze-drying) were used, the best extraction results were observed in the case of microwave drying and freeze-drying of melissa and thyme, respectively [ 22 ]. Importantly, these results only apply to “chemical extracts” [ 22 ]. In the case of dried lovage leaves, the jasmonic acid elicitation caused an increase in all phenolic acids identified in the potentially available fractions of phenolic compounds ( Table 1 ).…”

Section: Discussionmentioning

confidence: 99%

Effects of Drying Methods on Antioxidant, Anti-Inflammatory, and Anticancer Potentials of Phenolic Acids in Lovage Elicited by Jasmonic Acid and Yeast Extract

et al. 2021

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The study presents the effect of drying methods (traditional, convection, microwave, and freeze-drying) on the content and bioactivity (determined as antioxidative, anti-inflammatory, and antiproliferative potential) of potentially bioavailable fractions of phenolic acids contained in lovage elicited with jasmonic acid (JA) and yeast extract (YE) and in untreated control leaves. The highest amount of syringic acid was recorded in the convectionally dried lovage samples, while ethanolic extracts from lyophilized lovage had the highest content of protocatechuic and caffeic acids. The drying method significantly influenced the tested properties only in some cases. The traditional drying resulted in lower antioxidant potential, while convectional drying caused a reduction of the lipoxygenase inhibition ability of the samples after simulated digestion. Samples containing the control and elicited lovage leaves dried with convectional and traditional methods exhibited the highest cytotoxicity against a prostate cancer epithelial cell line.

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Changes in the Content of Phenolic Compounds and Biological Activity in Traditional Mexican Herbal Infusions with Different Drying Methods

Cited by 15 publications

References 39 publications

Effect of salicylic acid on phenolic compounds, antioxidant and antihyperglycemic activity of Lamiaceae plants grown in a temperate climate

Effect of salicylic acid on phenolic compounds, antioxidant and antihyperglycemic activity of Lamiaceae plants grown in a temperate climate

Characterization and Biological Activity of Fiber-Type Cannabis sativa L. Aerial Parts at Different Growth Stages

Effects of Drying Methods on Antioxidant, Anti-Inflammatory, and Anticancer Potentials of Phenolic Acids in Lovage Elicited by Jasmonic Acid and Yeast Extract

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