Changes in the neurosecretory cells, corpus cardiacum and corpus allatum during pregnancy in <i>Glossina austeni</i> Newst. (Diptera, Glossinidae)

Ejezie, G. C.; Davey, K. G.

doi:10.1017/s0007485300031138

Cited by 27 publications

(18 citation statements)

References 26 publications

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“…The low levels of GmmMGP immediately after birth suggests that its translation may cease until embryonic development of the next offspring has been completed and the next larva hatches into the uterus. Previous work suggests that milk production may be regulated via juvenile hormone, as the corpora allata (CA) (the gland responsible for juvenile hormone synthesis) undergoes cyclical changes in volume and histological appearance in parallel with the pregnancy cycle (Ejezie and Davey, 1974). Furthermore, ablation of the CA reduces milk synthesis in tsetse flies.…”

Section: Discussionmentioning

confidence: 99%

Molecular aspects of viviparous reproductive biology of the tsetse fly (Glossina morsitans morsitans): Regulation of yolk and milk gland protein synthesis

Attardo

Güz

Strickler-Dinglasan

et al. 2006

Journal of Insect Physiology

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Tsetse fly (Diptera: Glossinidae) viviparous reproductive physiology remains to be explored at the molecular level. Adult females carry their young in utero for the duration of embryonic and larval development, all the while supplying their offspring with nutrients in the form of a "milk" substance secreted from a modified accessory gland. Flies give birth to fully developed third instar larvae that pupariate shortly after birth. Here, we describe the spatial and temporal expression dynamics of two reproduction-associated genes and their products synthesized during the first and second gonotrophic cycles. The proteins studied include a putative yolk protein, Glossina morsitans morsitans yolk protein 1 (GmmYP1) and the major protein found in tsetse "milk" secretions (Glossina morsitans morsitans milk gland protein, GmmMGP). Developmental stage and tissue-specific expression of GmmYP1 show its presence exclusively in the reproductive tract of the fly during oogenesis, suggesting that GmmYP1 acts as a vitellogenic protein. Transcripts for GmmMGP are present only in the milk gland tissue and increase in coordination with the process of larvigenesis. Similarly, GmmMGP can be detected at the onset of larvigenesis in the milk gland, and is present during the full duration of pregnancy. Expression of GmmMGP is restricted to the adult stage and is not detected in the immature developmental stages. These phenomena indicate that the protein is transferred from mother to larvae as nourishment during its development. These results demonstrate that both GmmYP1 and GmmMGP are involved in tsetse reproductive biology, the former associated with the process of oogenesis and the latter with larvigenesis.

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Section: Discussionmentioning

confidence: 99%

Molecular aspects of viviparous reproductive biology of the tsetse fly (Glossina morsitans morsitans): Regulation of yolk and milk gland protein synthesis

Attardo

Güz

Strickler-Dinglasan

et al. 2006

Journal of Insect Physiology

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“…These neurosecretory cells belong to several categories (Ejezie and Davey, 1974;Foster, 1974;Nkouka, 1976;Panov, 1979; Grillot and Robert, unpublished results). In Clossina fuscipes, according to the terminology of Raabe et al (1979).…”

Section: Anatomical and Structural Datamentioning

confidence: 97%

Regulation of last reproduction steps in tsetse flies (Glossina:Diptera)

Grillot

Raabe²

1989

Invertebrate Reproduction & Development

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and 2Newoendocrinologie des Znsectes, CNRS UA 669, Universitt! P. and M. Curie, 12, rue Cuvier, 75252 Paris Ckdex 05, FranceThe regulation of ovulation and parturition, in the viviparous tsetse flies, constitutes a very pncisely adjusted mechanism. Indeed the process of vitekgenesis takes places, in one oocyte only, during the incubation period when the larva is nourished in utero on milk produced by the mother. Neuropeptides, biogenic amines, neurotransmitters as well as ecdysone, and 20-hydroxyecdysone and also nervous outputs regulate ovulation and pturition A model is proposed for the mechanisms controlling these processes.

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“…Cross talk among JH, E, IIS, the poorly defined parturition hormone (PH), and various neurosecretory factors is necessary to orchestrate lactation and parturition (11, 34, 41, 42, 77, 78, 83). Topical application of the developmental hormones JH or E induces larval abortion in G. morsitans (34).…”

Section: Tsetse Lactation and Underlying Mechanismsmentioning

confidence: 99%

“…The presence of duplicate JH receptors is thus conserved within Muscomorpha (137), and these proteins regulate divergent target genes as in Drosophila (40, 93). Investigators have examined JH action during tsetse reproduction by manipulating hormone titer (11, 34, 41, 42, 78, 83). Allatectomy (CAX), or removal of the corpus allatum, has been a popular approach for removing circulating JH in adults.…”

Section: Tsetse Lactation and Underlying Mechanismsmentioning

confidence: 99%

“…Additionally, JH can affect milk production. The average volume of the corpora allata in G. austeni fluctuates in accordance with the milk gland, reaching maximum size 2 days before both maximal milk gland size and synthetic activity during each cycle (41). CAX induces fat body hypertrophy and suppresses milk production; JH replacement therapy restores the capacity for lactation (42).…”

Section: Tsetse Lactation and Underlying Mechanismsmentioning

confidence: 99%

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Adenotrophic Viviparity in Tsetse Flies: Potential for Population Control and as an Insect Model for Lactation

Benoit

Attardo

Baumann

et al. 2015

Annu. Rev. Entomol.

107

102

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Tsetse flies (Glossina spp.), vectors of African trypanosomes, are distinguished by their specialized reproductive biology, defined by adenotrophic viviparity (maternal nourishment of progeny by glandular secretions followed by live birth). This trait has evolved infrequently among insects and requires unique reproductive mechanisms. A key event in Glossina reproduction involves the transition between periods of lactation and nonlactation (dry periods). Increased lipolysis, nutrient transfer to the milk gland, and milk-specific protein production characterize lactation, which terminates at the birth of the progeny and is followed by a period of involution. The dry stage coincides with embryogenesis of the progeny, during which lipid reserves accumulate in preparation for the next round of lactation. The obligate bacterial symbiont Wigglesworthia glossinidia is critical to tsetse reproduction and likely provides B vitamins required for metabolic processes underlying lactation and/or progeny development. Here we describe findings that utilized transcriptomics, physiological assays, and RNA interference–based functional analysis to understand different components of adenotrophic viviparity in tsetse flies.

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Changes in the neurosecretory cells, corpus cardiacum and corpus allatum during pregnancy in Glossina austeni Newst. (Diptera, Glossinidae)

Cited by 27 publications

References 26 publications

Molecular aspects of viviparous reproductive biology of the tsetse fly (Glossina morsitans morsitans): Regulation of yolk and milk gland protein synthesis

Molecular aspects of viviparous reproductive biology of the tsetse fly (Glossina morsitans morsitans): Regulation of yolk and milk gland protein synthesis

Regulation of last reproduction steps in tsetse flies (Glossina:Diptera)

Adenotrophic Viviparity in Tsetse Flies: Potential for Population Control and as an Insect Model for Lactation

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