Changes in the subcutaneous tissue of catheterization site from the precatheterization state to the onset of anticancer drug‐induced induration: A case report

Abstract

This report presents some of the changes in the subcutaneous tissue at the site of catheter insertion of a patient undergoing chemotherapy. The site was observed by ultrasonography at 5 time points, namely, before insertion, immediately after treatment, after 1, 3, and 4 weeks. Some practice guidelines do not recommend the use of a peripheral intravenous catheter for irritant or vesicant continuous administration to avoid vessel damage. 1,2 However, peripheral intravenous catheters are unavoidably used in some patients for drug administration because of their conditions, such as superior vena cava syndrome, coagulopathy, or compromised condition. In clinical settings, induration can be observed at the catheterization sites after anticancer drug administration even without obvious signs and symptoms of extravasation such as feelings of tingling, burning, pain, swelling, and redness at the

Damage to subcutaneous tissue at the catheterization site during chemotherapy: A prospective observational study using ultrasonography

“…Fifteen participants had some remaining abnormal findings or developed new abnormal findings in the subcutaneous tissue by the next treatment day, and eight of these participants had no subjective symptoms or induration. One previous case study reported a risk of overlooking subcutaneous damage on the next treatment day (1 week later) in a patient receiving weekly chemotherapy via a PIVC (Abe‐Doi et al, 2020b). The current study has now revealed that subcutaneous damage may be overlooked by conventional observation even 28 days after prior chemotherapy administration.…”