Changes in tinnitus after vestibular schwannoma surgery

Abstract

We designed a prospective study to evaluate changes in tinnitus after vestibular schwannoma (VS) surgery. Subjects included 41 patients who were diagnosed with a VS and underwent translabyrinthine microsurgery (TLM) between January 2015 and May 2016. All patients underwent related examinations and were asked to answer the Tinnitus Handicap Inventory (THI) scale and a visual analog scale (VAS) of tinnitus severity both pre- and postoperatively. Of the 41 patients, 31 (75.6%) suffered from tinnitus before surgery. Microsurgery was associated with an overall decrease in tinnitus (p < 0.001). There was a significant improvement in THI and VAS scores after surgery (p = 0.001 and p = 0.005, respectively). The decrease in THI scores in the low-frequency group was significantly larger than that of the mid- and high-frequency groups after surgery (p = 0.034 and p = 0.001, respectively). The loudness of tinnitus decreased significantly after surgery (p = 0.031). Tinnitus in patients with VS improved after TLM. Patients with mid-/high-frequency tinnitus and louder tinnitus preoperatively seemed to have a worse prognosis than those with low-frequency and quieter tinnitus.

Pediatric tinnitus: The role of neuroimaging

“…1 Tinnitus is a common symptom (>50%) in patients with vestibular schwannomas (Figure 11), and its preoperative severity can predict the postoperative prognosis of these patients with louder tinnitus associated with worse prognoses and poorer quality of life than patients with low-intensity tinnitus. 30 Vestibular schwannoma is a benign tumor of the vestibulocochlear nerve that typically arises from within the IAC and extends to the cerebellopontine angle. Unilateral and nonhereditary forms usually occur in middle-aged patients, while the bilateral form is described in patients younger than 21 years old with neurofibromatosis type 2.…”

“…In the presence of unilateral continuous tinnitus with unilateral or asymmetric hearing loss, audiometry and MRI are usually performed to evaluate for a vestibular schwannoma 1 . Tinnitus is a common symptom (>50%) in patients with vestibular schwannomas (Figure 11), and its preoperative severity can predict the postoperative prognosis of these patients with louder tinnitus associated with worse prognoses and poorer quality of life than patients with low‐intensity tinnitus 30 …”

Defining current practice patterns of vestibular schwannoma management in Italy: results of a nationwide survey

“…Considering symptom control, most respondents held that surgery has an unpredictable effect on tinnitus. Noteworthy, Wang et al 17 showed that microsurgical VS resection led to Tinnitus Handicap Index reduction in up to 77% of cases. Most surgeons in Italy and in North America considered that VS surgical removal led to a reduction or even to the resolution of preoperative dizziness.…”

Compositions and antimicrobial properties of binary ZnO–CuO nanocomposites encapsulated calcium and carbon from Calotropis gigantea targeted for skin pathogens

“…aeruginosa 2.5 2.5 16 E . coli 1.25 2.5 S. aureus 2.5 2.5 TiO 2 /ZnO/4A 10–50 E. coli 1 2 33 S. aureus 2 3 TiO 2 /ZnO – E . coli 5 10 46 S. aureus 5 10 K. pneumoniae 5 10 MRSA 0.15 0.30 ZnO-CuO Length: 8.126 and diameter: 7.515 P .…”