1968
DOI: 10.1159/000196830
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Changes of Structure and Enzyme Activity in Malabsorption during Gastrointestinal Paresis

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“…Overall, malabsorption syndromes can pertain to those which can affect the absorption of drugs and nutrients, may be drug-induced, or both. The main GI factors recognised for their involvement in drug malabsorption are numerous, ranging from available anatomical surface area to enzyme activity (Poka et al, 1968); changes to microbiota (Mortimer et al, 1964); food presence (Varum et al, 2013b); motility; intestinal and gallbladder obstruction (Collins et al, 1978;Parsons, 1977); pancreatitis (Dimagno et al, 1973); post-surgical causes and inflammatory disorders (Vitek, 2015). Drug and nutrient malabsorption is also a common consequence of surgical procedures and/or resections involving the stomach and small intestine, associated with anatomical changes including reduced surface area, peristalsis, transit time and gut wall metabolism (Titus et al, 2013), and will be discussed later in the review.…”
Section: Malabsorption Syndromesmentioning
confidence: 99%
“…Overall, malabsorption syndromes can pertain to those which can affect the absorption of drugs and nutrients, may be drug-induced, or both. The main GI factors recognised for their involvement in drug malabsorption are numerous, ranging from available anatomical surface area to enzyme activity (Poka et al, 1968); changes to microbiota (Mortimer et al, 1964); food presence (Varum et al, 2013b); motility; intestinal and gallbladder obstruction (Collins et al, 1978;Parsons, 1977); pancreatitis (Dimagno et al, 1973); post-surgical causes and inflammatory disorders (Vitek, 2015). Drug and nutrient malabsorption is also a common consequence of surgical procedures and/or resections involving the stomach and small intestine, associated with anatomical changes including reduced surface area, peristalsis, transit time and gut wall metabolism (Titus et al, 2013), and will be discussed later in the review.…”
Section: Malabsorption Syndromesmentioning
confidence: 99%