﻿Changes of ultrastructural organization in periodontal complex components in experimental periodontitis and its correction with quercetin

Demkovych, Andrii; Rubas, Lesia; Luchynskyi, Vitalii; Luchynska, Yuliia; Stoikevych, H. V.; Machogan, Volodymyr

doi:10.3897/pharmacia.69.e82128

Cited by 3 publications

(1 citation statement)

References 25 publications

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“…Its excess reduces the physical and mechanical properties of base plastics and causes premature "aging" of the material. In modern scientific periodicals there are some works devoted to the study of the influence of basic dental plastics on hematological parameters of blood [14][15][16]. The monomer is a strong organic solvent and promotes the activation of procoagulants, which are involved in the initial stages of blood clotting.…”

Section: іNtroductionmentioning

confidence: 99%

Аnalysis of the influence of basic acrylic plastics "Ftoraks" and "Villacryl H Plus" on the main hematological parameters in the experiment

Rosolovska,

Kindiy,

Hasiuk

et al. 2023

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Summary. The effectiveness of orthopedic treatment significantly depends on the properties of the basic plastics used in the manufacture of dentures. The aim of the study – to study the effect of acrylic plastics "Ftoraks" and "Villacryl H Plus", the polymerization of which was carried out by different methods, on the main hematological parameters. Materials and Methods. The study and comparative characterization of the possible toxic effects of dental base acrylic plastics "Ftoraks" and "Villacryl H Plus", which were polymerized by different methods, on the main hematological parameters were performed on white outbred rats, which implanted samples of these materials in periodontal tissue. Results and Discussion. As a result of the study, it was found that animals implanted with samples of the above acrylic plastics polymerized in a "water bath" methodic in the blood had a decrease of hemoglobin, leukocytosis, increased number of band and segment nuclear neutrophils, increase in the number of eosinophils and decrease of basophils in comparison with the control and other groups of animals. In the study of samples polymerized in the apparatus for dry polymerization under pressure and in the apparatus for molding plastics, it was found that fluctuations in the content of the main hematological parameters are within the physiological norm and do not differ significantly from the control. Сonclusions. Dental basic acrylic plastics "Ftoraks" and "Villacryl H Plus" polymerization of which was carried out by the method of dry polymerization with pressure and in the apparatus for foundry pressing of plastics cause less toxic effects on hematological parameters of the blood.

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Section: іNtroductionmentioning

confidence: 99%

Аnalysis of the influence of basic acrylic plastics "Ftoraks" and "Villacryl H Plus" on the main hematological parameters in the experiment

Rosolovska,

Kindiy,

Hasiuk

et al. 2023

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Characteristics of Thermoplastic Polymer Denture Base Materials for Prosthodontic Constructions

Poliukhovych,

Demkovych,

Bondarenko

2024

EUMJ

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Introduction. In dentistry, there is a wide range of thermoplastic polymers for the removable constructions of dental prostheses, which are extremely promising in modern dental practice. Successful prosthetics of patients will depend on the properties of the selected structural materials.. Purpose of the study was to summarize current information, based on a review of literary sources, on the use of thermoplastic base materials for the manufacture of removable prostheses and improves the effectiveness of orthopedic treatment of patients with complete or partial absence of teeth. Methods. A literature review was conducted using PubMed, Web of Science, SCOPUS, Google Scholar up to January 2024. There was no restriction on the date of publication or language. Searches using the MeSH (Medical Subject Headings) terms were conducted using synonyms and combinations of the following search terms: "removable prosthetics", "dental base materials", "thermoplastics" "materials science", and "adaptation". Used methods: bibliographic and analytical. Results. Thermoplastic materials are characterized by bioinertness for the organism, because they do not contain residual monomer. The technology of injection molding of thermoplastic polymers is considered as a promising technology in modern dentistry to achieve high aesthetic standards. The general characteristic of this group of materials is the absence of residual monomer and, accordingly, their biological indifference, a high level of plasticity, precision during the manufacture of the prosthesis, and a wide range of colours. Conclusion. Polymer denture base plastics do not have optimal physico-mechanical, biological and surface characteristics, so the search for new materials for the manufacture of removable prostheses remains a promising direction

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Modern views on the etiology and role of microbial persistence in the development of inflammatory processes in the periodontal complex (review)

Marfiian,

Demkovych,

Bondarenko

et al. 2024

Medicni Perspektivi

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Alveolar tissue diseases cause the appearance of dentition defects, thereby reducing the patients' work capacity and quality of life. The purpose of this research was to investigate, modern views on the etiology of periodontitis and the role of microbial persistence in the development of inflammatory processes of periodontal complex basing on a review of literary sources. Literature review was conducted using PubMed, Web of Science, Scopus, Google Scholar from 2018 to March 2024. There were no restrictions on the date of publication or the language of scientific sources. Searches were conducted according to MeSH (Medical Subject Headings) with using the following search terms: "periodontitis", "oral mucosa", "gums", "dental plaque", "periodontium", "traumatic occlusion", "microorganisms". In total, during the initial analysis 82 literary sources were selected and processed, after further systematization of the selected information using general scientific methods, 70 of them remained. Used methods: bibliographic and analytical. Generalized periodontitis is a chronic inflammatory-dystrophic process that occurs as a result of various factors. In the pathogenesis of this disease, the key role is played by the inflammatory process, which is a complex interaction of microcirculatory, hematological and connective tissue reactions to the lesion. Local (exogenic) and general (endogenic) causative factors are distinguished. The main factors that cause pathological changes in periodontium are bacterial biofilm, traumatic occlusion and various anatomical anomalies. Dental plaque occupies a special and main place among the causes of periodontitis. At present, leading pathogenetic links in the development of the inflammation in the periodontium, in particular, the disruption of free radical oxidation, the processes of peroxide oxidation of lipids and proteins, the disorder of the functional state of the antioxidant system, the formation of oxidative stress, as well as the humoral link of adaptive immune protection and cytokinesis, have not been sufficiently studied. There is no doubt about the role of the microbial factor in the etiology of periodontal diseases, but the penetration of microbes into the periodontium does not always lead to the development of the disease, because the organism has a number of protective mechanisms that counteract the development of inflammation.

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Changes of ultrastructural organization in periodontal complex components in experimental periodontitis and its correction with quercetin

Cited by 3 publications

References 25 publications

Аnalysis of the influence of basic acrylic plastics "Ftoraks" and "Villacryl H Plus" on the main hematological parameters in the experiment

Аnalysis of the influence of basic acrylic plastics "Ftoraks" and "Villacryl H Plus" on the main hematological parameters in the experiment

Characteristics of Thermoplastic Polymer Denture Base Materials for Prosthodontic Constructions

Modern views on the etiology and role of microbial persistence in the development of inflammatory processes in the periodontal complex (review)

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﻿Changes of ultrastructural organization in periodontal complex components in experimental periodontitis and its correction with quercetin

Cited by 3 publications

References 25 publications

Аnalysis of the influence of basic acrylic plastics "Ftoraks" and "Villacryl H Plus" on the main hematological parameters in the experiment

Аnalysis of the influence of basic acrylic plastics "Ftoraks" and "Villacryl H Plus" on the main hematological parameters in the experiment

Characteristics of Thermoplastic Polymer Denture Base Materials for Prosthodontic Constructions

Modern views on the etiology and role of microbial persistence in the development of inflammatory processes in the periodontal complex (review)

Contact Info

Product

Resources

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Changes of ultrastructural organization in periodontal complex components in experimental periodontitis and its correction with quercetin