Changing incidence and residual lifetime risk of common osteoporosis-related fractures

Abstract

Changes in incidence and lifetime risk of fractures are of major importance in the epidemiology of osteoporosis. We focused on hip fractures in women and men and on radial and humeral fractures in women. The study subjects comprised 4500 women and men 20 years old or more with fractures. In women 1735 fractures of the distal radius, 747 fractures of the proximal humerus, 878 cervical and 635 trochanteric hip fractures were included. In men 273 cervical and 232 trochanteric hip fractures were included. The fractures were registered during the period 1976 to 1984 and changes in age-specific incidence were calculated (chi-squared test for linear trend; p-values less than 0.05 were considered significant). On the basis of life tables and population background data, the lifetime risk was estimated. The incidence of cervical hip fractures in women aged 60-89 years decreased significantly (p < 0.05) during the observation period, while no significant decrease was found in the incidence of trochanteric fractures. No significant changes in incidence were observed in women with radial or humeral fractures, or in men with hip fractures. A women 60 years old with a life expectancy of 81 years had an estimated residual lifetime risk of radial, humeral or hip fracture of 17%, 8% and 14% respectively. A man 60 years of age with a life expectancy of 77 years had an estimated risk of hip fracture of 6%.(ABSTRACT TRUNCATED AT 250 WORDS)

Lifetime Risk of ESRD

“…It has been suggested that lifetime risk estimates are useful for public education, because they are easier to comprehend than measures such as incidence, prevalence, or relative risk. 4 Although estimates of lifetime risk are available for several chronic disease conditions, including coronary heart disease, 5,6 stroke, 7,8 hypertension, 9 diabetes, 10 breast cancer, 11 dementia, 12 and fractures, 13,14 reports on the lifetime risk of ESRD are scarce and limited to an early-adult population. 15 Furthermore, the lifetime risk of ESRD at middle age and the lifetime risk of ESRD by level of kidney function have not been reported.…”

Can the displacement of a conservatively treated distal radius fracture be predicted at the beginning of treatment?

“…The RS (2) behaves in a very similar manner (RS injury =5 mm, RS red =3 mm, RS end =4 mm) have a considerable effect on the clinical outcome and patient satisfaction. An effect on the outcome has been demonstrated in the past for various factors, such as the patient's age [18] or osteoporosis and pre-existing osteoarthritic changes in the radiocarpal joint [5,13]. While none of these factors can be influenced therapeutically, the bone healing outcome can.…”

Cardioorthopedics — is it necessary in clinical practice? A study of patients with hip replacement surgery

“…The annual incidence of hip fracture was estimated to be 1.66 million worldwide in 1990 and is expected to reach 6.26 million by 2050 due to the aging population [11]. The majority of hip fractures occur in geriatric patients: approxi mately 80% of women and 50% of men with hip fractures are aged ≥ 70 years [12].…”