2004
DOI: 10.1001/archinte.164.11.1214
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Changing Patterns in Causes of Death in a Cohort of Injecting Drug Users, 1980-2001

Abstract: Injecting drug users have a very high risk of mortality. Infectious diseases from nonsterile injecting are the most obvious preventable cause of death. Use of death certificate information alone is inaccurate in analyzing drug-related deaths and greatly underestimates the full impact of the HIV epidemic. This study provides some of the most convincing evidence so far that harm minimization, in its broadest sense, is effective in reducing drug-related mortality.

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Cited by 79 publications
(51 citation statements)
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“…[3][4][5][6][7][8] While mortality rates cannot be directly compared across studies without age or sex adjustment, our results appear to be consistent with other literature reports. A prospective study of mortality among drug users after treatment showed an equally high mortality rate (1.2%), which was six times higher than that for a general, agematched population.…”
Section: Discussionsupporting
confidence: 92%
See 2 more Smart Citations
“…[3][4][5][6][7][8] While mortality rates cannot be directly compared across studies without age or sex adjustment, our results appear to be consistent with other literature reports. A prospective study of mortality among drug users after treatment showed an equally high mortality rate (1.2%), which was six times higher than that for a general, agematched population.…”
Section: Discussionsupporting
confidence: 92%
“…23 The annual mortality rate for people with opioid abuse in a 12-year follow-up study was 1.4%, 4 and among subjects with a history of injection drug use in Scotland, the average annual mortality rate was 2.3% over a 21-year period. 7 These rates are all similar to the 1.7% per year rate in our study and our finding of increased mortality compared with the general population.…”
Section: Discussionsupporting
confidence: 91%
See 1 more Smart Citation
“…[1][2][3][4] Excess risk of mortality among drug users has been attributed to HIV infection, drug overdosing, and violence. [5][6][7] Fluctuations over time in the relative influence of different causes of death have also been noted. During the 1990s, several studies reported decreasing death rates due to HIV infection among drug users and attributed the downward trends to the new HIV medication regimens.…”
Section: Introductionmentioning
confidence: 93%
“…Despite high prevalence of HCV infection, the risk of HCV related death among active opiate users is low (10), and the dominant causes of excess mortality are drug overdose, suicide, trauma and in some populations also HIV/AIDS (3,(8)(9)(10). However, directly drug related mortality is reduced in patients receiving OST, (11,12).…”
Section: Introductionmentioning
confidence: 99%