Changing target temperature from 33 °C to 36 °C in the ICU management of out-of-hospital cardiac arrest: A before and after study

High Quality Targeted Temperature Management (TTM) After Cardiac Arrest

“…In one study, when TTM was strictly maintained at target values using a surface method with temperature feedback to constantly adjust the intensity of cooling, there was no difference in patient outcomes between a target of 33°C and one of 36°C [24]. However, in a before-after study comparing change in TTM target from 33 to 36°C, there was poor compliance with the higher target temperature resulting in reduced times in target and increased fever rates; there was also a 15% reduction in patients with favorable neurological outcome compared to the earlier period [25]. Similar results were observed in other studies [26,27].…”

The present and future of cardiac arrest care: international experts reach out to caregivers and healthcare authorities

“…There is inconclusive evidence whether any temperature target is better than another, and there is variation in practice throughout Europe [60] as well as North America. If the target is 36 °C, efforts should be made to stay within target and avoiding higher temperatures [61]. The recommended duration of TTM should be at least 24 h [62].…”

State‐of‐the‐art considerations in post‐arrest care

“…In one small retrospective study, the goal temperature in post‐cardiac arrest patients was changed from 33°C (n = 24) to 36°C (n = 52). In the 36°C group, there was significantly less utilization of active cooling (100% in the 33°C group vs 70% in the 36°C group), less time spent at the target temperature (87% in the 33°C group vs 50% in the 36°C group), and an increase in rates of fever (0% in the 33°C group vs 19% in the 36°C group) 38 . The data showed a trend toward worse neurologic outcomes in the 36°C group.…”