The combined analysis of past evolutionary trajectories of channel morphology and temporal patterns of driving factors is fundamental to understanding present river conditions, supporting river management and evaluating future changes. Rivers in Europe underwent important channel changes during the Anthropocene in response to changing natural drivers and anthropogenic pressures. A considerable number of papers have been published on this topic, in the last decades. In this study, a comprehensive meta‐analysis on channel changes during the last 200 years in Europe was performed, aiming to provide quantitative information on the intensity of changes, to highlight regional scale similarities and dissimilarities in evolutionary morphological trajectories and to discuss the main causes of such changes. Based on a review, 102 papers were selected, addressing 145 channel reaches flowing through five main mountain ranges (Iberians, Alps, Apennines, Balkans and Carpathians) in the southern and eastern parts of Europe. The results show that active channel narrowing (between 26% and 36% on average) and incision (between 1 and 2 m) prevailed in most rivers between the 1800s and the 1950s, although widening was documented in some rivers of the Alps and the Apennines. Most multi‐thread reaches maintained their pattern until the mid‐20th century. Active channel changes accelerated during the 1950s–1990s (or 2000s) period, with channel narrowing up to 60% and channel incision up to 14 m. Multi‐thread patterns strongly decreased in frequency, with anabranching channels disappearing and single‐thread patterns becoming predominant. The cumulative effect of multiple and concomitant human pressures (gravel mining, channelisation and damming) was identified as the main driving factor for these accelerated changes. These findings must feed the public debate about preventing alterations of river ecosystems—exerted by anthropic disturbances—in a context of rapid economic development, especially in river systems still poorly altered and thus preserving wide, active and heterogeneous fluvial corridors.