“…These studies involved various enzyme families such as RNAses (Christensen & Gerdes, 2003;Kamada et al, 2003;Kamada & Hanaoka, 2005;Winther & Gerdes, 2011), kinases (Castro-Roa et al, 2013;Kaspy et al, 2013;Mutschler et al, 2011), ADP-ribosyl transferases (Jankevicius et al, 2016), acetyltransferases (Cheverton et al, 2016;Jurė nas, Chatterjee et al, 2017) and adenylyltransferases (Engel et al, 2012). In addition, the different mechanisms of toxin neutralization and transcription autoregulation show that the intrinsically disordered regions present in TA antitoxins constitute an important feature of type II TA modules (Bordes et al, 2016;De Gieter et al, 2014;Garcia-Pino, Balasubramanian et al, 2010;Garcia-Pino et al, 2016; beyond providing a target for protease degradation. The toxin AtaT from the ataRT TA module found in enteropathogenic E. coli, Enterobacter, Citrobacter and other bacteria (Jurė nas, Garcia-Pino et al, 2017) was recently described as a member of the GNAT family of N-acetyltransferases.…”