Chapter 11. Novel Approaches to Exploit Natural Products from Microbial Resources

Since the time Van Leeuwenhoek was able to observe microbes through a microscope, an innovation that led to the birth of the field of microbiology, we have aimed to understand how microorganisms function, interact and communicate. The exciting progress in the development of analytical technologies and workflows has demonstrated mass spectrometry as very powerful technique for the interrogation of microbiology at the molecular level. In this review, we aim to highlight the available and emerging tools in mass spectrometry for microbial analysis by overviewing the methods and workflow advances for taxonomic identification, microbial interaction, dereplication and drug discovery. We emphasize their potential for future development, point out unsolved problems and future directions that would aid in the analysis of the chemistry produced by microbes.

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Mass spectrometry tools and workflows for revealing microbial chemistry

Luzzatto-Knaan

Melnik

Dorrestein

2015

Analyst

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Chapter 11. Novel Approaches to Exploit Natural Products from Microbial Resources

Cited by 1 publication

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Mass spectrometry tools and workflows for revealing microbial chemistry

Mass spectrometry tools and workflows for revealing microbial chemistry

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