The active volcanic front in Colombia is divided into three main segments: The southern volcanic segment in the Western Cordillera and Inter-Andean Cauca-Patía Valley and the central and northern segments in the Central Cordillera, which are separated by a gap of 265 km. The recent volcanoes of the volcanic front are large polygenetic structures mostly built on the remnants of a Miocene -Pliocene volcanic terrain. The variety of eruptive styles and the composition and distribution of the volcanoes reflect the configuration of the Nazca Plate subducting beneath the continent, the interaction of plates and microplates at the NW corner of South America, and the tectonic structures in the Eastern Panamá Basin generated by the rupture of the Farallón Plate in the Miocene. Compositionally, the magmatic products of these volcanoes correspond to basaltic andesites, andesites, and dacites. Additionally, the most recent products of the volcanoes located in the central volcanic segment and at the ends of the other segments exhibit adakitic signatures and the most explosive behavior, usually of plinian type. The origin of the magmas has been attributed to several processes, including mantle melting, slab fluid-induced metasomatism of the mantle wedge, crustal contamination, magma mixing, and fractional crystallization. However, the processes that occur between the magma source and the lower crust, such as those related to the sizes and locations of magma chambers and the plumbing systems, are poorly understood. In the last 34 years, since the beginning of the systematic study of active volcanoes in 1985 and their continuous monitoring by the Servicio Geológico Colombiano, understanding of the superficial processes, stratigraphy, and eruptive history has progressed. Several of these volcanoes have a record of historical activity, such as Nevado del Ruiz, Puracé, Doña Juana, and Galeras. In recent years, some volcanoes have had eruptive activity, such as Nevado del Ruiz, Galeras, and Nevado del Huila, while others have shown signs of reactivation, such as Cerro Machín, Chiles-Cerro Negro, and Sotará. This chapter compiles the main characteristics of recent volcanism in Colombia in a tectonic context and summarizes the historical volcanic activity in this region.