Chapter 50. Strontium Ranelate in the Prevention of Osteoporotic Fractures

Rizzoli, René

doi:10.1002/9780470623992.ch50

Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism 2008

DOI: 10.1002/9780470623992.ch50

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Chapter 50. Strontium Ranelate in the Prevention of Osteoporotic Fractures

René Rizzoli¹

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2009

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Evaluation and Management of Osteoporosis and Fragility Fractures in The Elderly

Rosenzweig

Mishra²

2009

Aging Health

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Osteoporosis is characterized by low bone mass and microarchitectural deterioration that leads to increased bone fragility and fracture. The medical, psychosocial and economic burden that fragility fractures have on individuals and society is staggering. As the geriatric segment of the population continues to expand, so to will the magnitude of this epidemic. There are multiple mechanisms influencing bone quality and bone loss with age. Fragility fracture is a composite of multiple intrinsic and extrinsic factors related to the individual and their environment. Fall prevention remains the cornerstone of management in this problem. The FRAX® fracture risk assessment program, which estimates the 10-year probability of a major osteoporotic fracture, is an exciting new tool in assessing risk. Novel therapeutics, including zoledronic acid, strontium and teriparatide, are now available to complement proven osteoporosis treatments and more effectively decrease fracture risk in vulnerable individuals. Agents in Phase III trials, including denosumab and lasofoxifene, will probably increase the armamentarium of tools clinicians can use to combat the growing problem of osteoporosis and its complications.

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Evaluation and Management of Osteoporosis and Fragility Fractures in The Elderly

Rosenzweig

Mishra²

2009

Aging Health

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Chapter 50. Strontium Ranelate in the Prevention of Osteoporotic Fractures

Cited by 1 publication

References 25 publications

Evaluation and Management of Osteoporosis and Fragility Fractures in The Elderly

Evaluation and Management of Osteoporosis and Fragility Fractures in The Elderly

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