Chapter 8 Control of intestinal diseases by dietary supplementation with antibodies

Stefaniak, Tadeusz

doi:10.1016/s1877-1823(09)70095-5

Cited by 2 publications

(2 citation statements)

References 123 publications

(126 reference statements)

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“…Because of high costs of vaccination of pregnant cows and treatment of calves with diarrhoea other methods of specific protection are searched. The supplementary oral application of antibodies for specific protection of alimentary tract after colostral period seems logical (Stefaniak 2006). One of low-cost and efficient methods is oral application of egg yolk (IgY) antibodies (Ikemori et al 1992, Mine and Kovacs-Nolan 2002, Stefaniak 2006.…”

Section: Introductionmentioning

confidence: 99%

“…Approximately 1500 mg of IgY may be harvested every month from each laying hen (5-25 mg/ml egg yolk), with between 2 and 10% being antigen-specific IgY, representing a faster and cheaper way of polyclonal Ab production than other sources (Vega et al 2011). It exceeds several times the yield of serum Igs from rabbits, pigs and from cow colostrum (Hatta et al 1993, Mine and Kovacs-Nolan 2002, Stefaniak 2006. Large-scale production of eggs and their processing is easier than other sources of Igs.…”

Section: Introductionmentioning

confidence: 99%

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Production and characterization of egg yolk antibodies against bovine alimentary tract pathogens

Sitnik¹,

Jawor²,

Kopeć³

et al. 2013

Polish Journal of Veterinary Sciences

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Aim of the study was to evaluate the effect of immunization of hens with bovine vaccines (C, R, T) on the course of IgY antibodies production against selected bovine E.coli strains, rota-and coronaviruses in egg yolk in farm conditions. The hens (40 individuals per group) were vaccinated twice, subcutaneously in four week interval and eggs were harvested once a week. Control group consisted of eggs sampled from non-vaccinated hens located in neighbouring cages. The antibody activity was measured by ELISA. All used vaccines induced the rise of IgY antibody in egg yolks. Based on the duration and the highest level of IgY antibody against bovine alimentary tract pathogens C vaccine was further used in next two trials for vaccination of 1000 hens each time. Double immunization seems to be enough in mounting response against examined pathogens for several weeks. Immunization with C vaccine allowed to harvest eggs with satisfactory levels of E.coli, rotavirus and coronavirus IgY antibodies which may be used to evaluate their protective effect by oral administration in calves.

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Section: Introductionmentioning

confidence: 99%