Herein, the carbon black/graphene oxide/natural rubber composites (CB/GO/NR) with different crosslink networks were prepared through the latex co-precipitation approach. Meanwhile, the type of crosslinks on the crack propagation resistance and fatigue life in different vulcanized systems were investigated. As a result, CB/GO/NR composites dominated by polysul de in conventional vulcanization (CV) system exhibited the improved tear strength (71.6 KN/m) and lowest crack growth rate (64.1 nm/cycle), the developed crosslink network and polysul de based crosslink structure in CV system were the key factors to improve the crack propagation resistance. In addition, the relationship between viscoelasticity and dynamic crack propagation behavior of CB/GO/NR was studied, and the CV system had the lowest loss compliance modulus( J "), thus more energy dissipation occurred in the crack propagation region and the crack propagation resistance of CV system was improved. Importantly, this work can provide the guideline for designing the rubber-based composites in the practical engineering applications.