Characterisation of breast implant surfaces and correlation with fibroblast adhesion

Biocompatible polyhydroxyalkanoates/bacterial cellulose composites: Preparation, characterization, and in vitro evaluation

“…PHB‐A/BC2 composite showed the best mechanical properties, the highest roughness and a medium hydrophobicity in this series but also the best behavior at in vitro evaluation. This means that fibroblast adhesion and proliferation was enhanced by the higher roughness and stiffness, similar to other observations . but also by a medium contact angle, of 74–75.…”

“…On the other hand, the increased concentration of the hydrophilic filler led to lower CA values, obvious in composites with 2 and 5 wt % BC. Cell proliferation is also influenced by a multitude of factors, but the surface tension, roughness and mechanical properties of the substrate seem the most important . PHB‐A/BC2 composite showed the best mechanical properties, the highest roughness and a medium hydrophobicity in this series but also the best behavior at in vitro evaluation.…”

The effect of post-mastectomy radiation therapy on breast implants: Unveiling biomaterial alterations with potential implications on capsular contracture

“…Moreover, investigations on chemical structure, topography, and mechanical properties of different commercially available breast implants have been widely undertaken [8,21,22]. From these studies, a leading effect of physico-chemical and mechanical properties on cell adhesion has been clearly evidenced [13].…”

“…Mechanical properties of breast implants have been examined due to their proven effect on implant surface-fibroblasts interaction [13]. Fig.…”

Prevention of Capsular Contracture with Photochemical Tissue Passivation

“…16 Recent research has found that the use of textured implants can result in decreased fibrosis and a nonpathogenic orientation of fibroblasts and collagen fibers. 17,18 Altering the implant structure is one solution to capsular contracture; however, at this time, all implants are composed of synthetic material and will continue to elicit a foreign body response. We hoped that by changing the structure of the implant pocket we could blunt this response and alter how the capsule forms and contracts.…”