Characterisation of Novel Topical Olive Oil Oleohydrogel Hybrid for Controlled Drug Release

Ash, Dipanjana; Majee, Sutapa Biswas; Avlani, Dhruti

doi:10.47583/ijpsrr.2020.v64i01.024

Cited by 2 publications

(1 citation statement)

References 20 publications

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“…In addition, the functional beverages market is predicted to grow from $71.5 billion in 2016 to $105.5 billion in 2021, with a compounded yearly growth rate of 8.1% over the same 4]. [8]…”

Section: Global Nutritional Supplements Marketmentioning

confidence: 99%

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2023

IJGP

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In 1989, the Foundation for Innovation in Medicine (New York, US) created the term "nutraceutical" to name the rapidly expanding area of biomedical research. Nutraceuticals are defined as food or dietary components that offer medical or health benefits to the body, including disease prevention and treatment. Nutraceuticals are viewed as a more natural way to achieve therapeutic effects with fewer side effects, and this perspective has transformed the development and production of nutraceuticals into a multi-billion-dollar industry. The nutraceutical market is expected to reach $1025 billion by 2030, with a CAGR of 8.33% from 2022 to 2030. Nutraceuticals are gaining popularity due to their potential nutritional, safety, and therapeutic benefit. Current research has demonstrated that these chemicals have potential results in a variety of complications. The regulatory status of nutraceuticals varies by country or region. The food and drug administration (FDA) regulates nutraceuticals as dietary supplements in the United States under the dietary supplement health and education act (DSHEA) of 1994. According to this regulation, dietary supplements are products with one or more nutritional components, such as vitamins, minerals, herbs, or other botanicals, that are meant to supplement the diet. Nutraceuticals do not require FDA pre-market approval under DSHEA, and the manufacturer is responsible for product safety and labeling. The FDA, on the other hand, has the jurisdiction to investigate companies that make false or misleading statements about the safety or effectiveness of their products. This article provides a brief overview of the nutraceuticals regulation established by the US FDA in the United States and the Food Safety Standard Authority of India in India. Finally, the nutraceutical industry is expanding rapidly, due to rising consumer awareness of the necessity of leading a healthy lifestyle. Regulatory authorities around the world are responsible of guaranteeing the safety and efficacy of nutraceuticals, and rules vary from country to country. As the market expands, it is critical for regulatory agencies to stay ahead of the latest industry advancements to protect customer safety and trust.

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“…In addition, the functional beverages market is predicted to grow from $71.5 billion in 2016 to $105.5 billion in 2021, with a compounded yearly growth rate of 8.1% over the same 4]. [8]…”

Section: Global Nutritional Supplements Marketmentioning

confidence: 99%

Untitled

2023

IJGP

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Organogels: “GelVolution” in Topical Drug Delivery - Present and Beyond

Nikam,

Roy,

Raychaudhuri

et al. 2024

CPD

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Topical drug delivery holds immense significance in dermatological treatments due to its non-invasive nature and direct application to the target site. Organogels, a promising class of topical drug delivery systems, have acquired substantial attention for enhancing drug delivery efficiency. This review article aims to explore the advantages of organogels, including enhanced drug solubility, controlled release, improved skin penetration, non-greasy formulations, and ease of application. The mechanism of organogel permeation into the skin is discussed, along with formulation strategies, which encompass the selection of gelling agents, cogelling agents, and additives while considering the influence of temperature and pH on gel formation. Various types of organogelators and organogels and their properties, such as viscoelasticity, non-birefringence, thermal stability, and optical clarity, are presented. Moreover, the biomedical applications of organogels in targeting skin cancer, anti-inflammatory drug delivery, and antifungal drug delivery are discussed. Characterization parameters, biocompatibility, safety considerations, and future directions in optimizing skin permeation, ensuring long-term stability, addressing regulatory challenges, and exploring potential combination therapies are thoroughly examined. Overall, this review highlights the immense potential of organogels in redefining topical drug delivery and their significant impact on the field of dermatological treatments, thus paving the way for exciting prospects in the domain.

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Characterisation of Novel Topical Olive Oil Oleohydrogel Hybrid for Controlled Drug Release

Cited by 2 publications

References 20 publications

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Organogels: “GelVolution” in Topical Drug Delivery - Present and Beyond

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