2016
DOI: 10.1183/13993003.01565-2015
|View full text |Cite|
|
Sign up to set email alerts
|

Characterisation of patients with interstitial pneumonia with autoimmune features

Abstract: Patients with interstitial lung disease (ILD) may have features of connective tissue disease (CTD), but lack findings diagnostic of a specific CTD. A recent European Respiratory Society/American Thoracic Society research statement proposed criteria for patients with interstitial pneumonia with autoimmune features (IPAF). We applied IPAF criteria to patients with idiopathic interstitial pneumonia and undifferentiated CTD-ILD (UCTD). We then characterised the clinical, serological and morphological features of t… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
2
1

Citation Types

38
342
16
21

Year Published

2016
2016
2023
2023

Publication Types

Select...
6
2

Relationship

0
8

Authors

Journals

citations
Cited by 241 publications
(417 citation statements)
references
References 23 publications
38
342
16
21
Order By: Relevance
“…We read with great interest the study by VARDAVAS et al [1] confirming the independent and interacting roles of tobacco smoke exposure during pregnancy and after birth in the development of respiratory diseases.…”
Section: Smoke-free Legislation and Its Impact On Paediatric Respiratmentioning
confidence: 89%
“…We read with great interest the study by VARDAVAS et al [1] confirming the independent and interacting roles of tobacco smoke exposure during pregnancy and after birth in the development of respiratory diseases.…”
Section: Smoke-free Legislation and Its Impact On Paediatric Respiratmentioning
confidence: 89%
“…OLDHAM et al [6] retrospectively applied IPAF criteria to a cohort of 422 patients diagnosed with IIP, interstitial pneumonia associated with UCTD or unclassifiable ILD. The finding that approximately one-third of the initial cohort (n=144) met IPAF criteria confirmed earlier reports [4,7,8] that features of CTD are common in patients with IIP.…”
Section: @Erspublicationsmentioning
confidence: 99%
“…Survival mirrored that in CTD-ILD, but this subgroup consisted of 40 of the 46 IPAF patients with non-UIP patterns, who were also characterised by a CTD-ILD-like outcome. Due to major subgroup overlap of this sort and the lack of powering for other outcome analyses, the nuanced prognostic distinctions reported by OLDHAM et al [6] will need to be tested in future cohorts. What can be concluded with confidence is that, within patients meeting IPAF criteria, the distinction between a UIP and a non-UIP pattern, whether on HRCT or biopsy, has major prognostic significance.…”
Section: @Erspublicationsmentioning
confidence: 99%
“…In conclusion, this study by OLDHAM et al [37] is an important first step in evaluating the new IPAF classification criteria, providing useful insights into the characterisations of clinical, morphological and serological features of IPAF in NSIP-OP, IPF, unclassifiable IIPs and UCTD-ILD patients. The strongest message of this study is that the outcome difference in IPAF is primarily linked to the underlying presence of UIP [38], which shows a prognosis similar to IPF, and we believe should be managed accordingly until existing uncertainties are clarified by future studies.…”
Section: Clarifying the Features Of Ipafmentioning
confidence: 99%
“…IPAF was created as a research category, intended to provide a sound platform for the prospective study of these patients. With the aim of characterising the features of IPAF and defining its prognosis in comparison to other DPLDs, OLDHAM et al [37] applied IPAF criteria to a series of 422 patients with IIPs (NSIP, IPF, cryptogenic organising pneumonia (COP) and unclassifiable IIPs) and undifferentiated CTD (UCTD)-associated ILD. A large subgroup of patients (34%, n=144) met the IPAF criteria (30% of NSIP, 60% of COP, 20% of IPF, 25% of unclassifiable IIPs and 91% of UCTD-ILD).…”
Section: Clarifying the Features Of Ipafmentioning
confidence: 99%