Characterisation of typical enteropathogenic Escherichia coli (tEPEC) lineages and novel bfpA variants detected in Australian fruit bats (Pteropus poliocephalus)

McDougall, Fiona; Gordon, David; Robins-Browne, Roy; Bennett-Wood, Vicki; Boardman, Wayne S.J.; Graham, Petra L.; Power, Michelle

doi:10.1016/j.scitotenv.2023.166336

Cited by 2 publications

(1 citation statement)

References 81 publications

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“…Salmonella enterica has been detected in grey-headed flying-foxes in New South Wales ( McDougall and Power, 2021 ; Van Brussel et al, 2023 ); however, they are not considered major reservoirs for Salmonella , as the prevalence is very low (0.4%; 1/254) ( McDougall and Power, 2021 ). Similarly, enteropathogenic Escherichia coli (EPEC) has been detected in 17.4% of grey-headed flying-fox faecal samples collected from New South Wales and South Australia; however, whole genome sequencing suggested that the bats were carrying mostly bat-specific lineages of EPEC ( McDougall et al, 2023 ).…”

Section: Zoonotic Risk Of Cryptosporidium and ...mentioning

confidence: 99%

How significant are bats as potential carriers of zoonotic Cryptosporidium and Giardia?

Barbosa,

Egan,

Feng

et al. 2023

Current Research in Parasitology & Vector-Borne Diseases

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Section: Zoonotic Risk Of Cryptosporidium and ...mentioning

confidence: 99%

How significant are bats as potential carriers of zoonotic Cryptosporidium and Giardia?

Barbosa,

Egan,

Feng

et al. 2023

Current Research in Parasitology & Vector-Borne Diseases

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Dynamics of Antimicrobial Resistance Carriage in Koalas (Phascolarctos Cinereus) and Pteropid Bats (Pteropus Poliocephalus) Before, During and After Wildfires

McDougall,

Speight,

Funnell

et al. 2024

Microb Ecol

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In the 2019–2020 summer, wildfires decimated the Australian bush environment and impacted wildlife species, including koalas (Phascolarctos cinereus) and grey headed flying fox pups (Pteropid bats, Pteropus poliocephalus). Consequently, hundreds of koalas and thousands of bat pups entered wildlife hospitals with fire-related injuries/illness, where some individuals received antimicrobial therapy. This study investigated the dynamics of antimicrobial resistance (AMR) in pre-fire, fire-affected and post-fire koalas and Pteropid bat pups. PCR and DNA sequencing were used to screen DNA samples extracted from faeces (koalas and bats) and cloacal swabs (koalas) for class 1 integrons, a genetic determinant of AMR, and to identify integron-associated antibiotic resistance genes. Class 1 integrons were detected in 25.5% of koalas (68 of 267) and 59.4% of bats (92 of 155). Integrons contained genes conferring resistance to aminoglycosides, trimethoprim and beta-lactams. Samples were also screened for blaTEM (beta-lactam) resistance genes, which were detected in 2.6% of koalas (7 of 267) and 25.2% of bats (39 of 155). Integron occurrence was significantly higher in fire-affected koalas in-care compared to wild pre-fire koalas (P < 0.0001). Integron and blaTEM occurrence were not significantly different in fire-affected bats compared to pre-fire bats (P > 0.05), however, their occurrence was significantly higher in fire-affected bats in-care compared to wild fire-affected bats (P < 0.0001 and P = 0.0488 respectively). The observed shifts of AMR dynamics in wildfire-impacted species flags the need for judicious antibiotic use when treating fire-affected wildlife to minimise unwanted selective pressure and negative treatment outcomes associated with carriage of resistance genes and antibiotic resistant bacteria.

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Characterisation of typical enteropathogenic Escherichia coli (tEPEC) lineages and novel bfpA variants detected in Australian fruit bats (Pteropus poliocephalus)

Cited by 2 publications

References 81 publications

How significant are bats as potential carriers of zoonotic Cryptosporidium and Giardia?

How significant are bats as potential carriers of zoonotic Cryptosporidium and Giardia?

Dynamics of Antimicrobial Resistance Carriage in Koalas (Phascolarctos Cinereus) and Pteropid Bats (Pteropus Poliocephalus) Before, During and After Wildfires

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