Characteristic Features of Coronavirus Disease-2019 (COVID-19) Pandemic: Attention to the Management and Control in Egypt

Abstract

In the late of 2019, unfamiliar cases of pneumonia were announced in Wuhan City, Hubei Province, China that resulted in high mortality rates of 2%. Shortly, these cases were reported to be brought about by a novel type of coronaviruses named as novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The disease caused by this novel virus is designated as coronavirus disease-2019 (COVID-19). Instantly afterwards, this disease exhibited an extreme spreading rate and the infection has geographically shifted to affect the whole world including the Middle East countries involving Egypt. Thus, it is not surprising that a lot of reports and literature have been directed to provide information and describe the clinical features of this pandemic. In this report, we describe in details the characteristic features of COVID-19 pandemic with attention to the management and control in Egypt. Characters of the virus, mode of transmission, pathogenesis, clinical symptoms, diagnosis, treatment, and prevention are fully described.

Thiazole‐based SARS‐CoV‐2 protease (COV Mpro) inhibitors: Design, synthesis, enzyme inhibition, and molecular modeling simulations

“…Also, it can affect the gastrointestinal tract and central nervous system and may lead to death. [ 2 , 3 , 4 ] According to the announced World Health Organization situational reports, many SARS‐CoV‐2 infection cases were globally confirmed, including numerous deaths, and great attention was paid by medicinal chemists to find a medication for treatment. [ 5 ] SARS‐CoV‐2 belongs to a large virus family called coronaviruses (Coronaviridae) that share single‐stranded RNA surrounded by a membrane envelope supplied with spikes that give them the characteristic crown‐like appearance.…”