Characteristic of nasopharyngeal carcinoma patients in Sanglah General Hospital Denpasar period 2016-2020

Abstract

Introduction: Nasopharyngeal carcinoma (NPC) is the most common head and neck malignancy in Indonesia and ranks it as the fourth most common among all malignancies in Indonesia. In Indonesia, it is estimated that the incidence of NPC is 6.2 per 100,000 population or 12,000 new cases per year. The initial stage of the NPC is difficult to establish because of location of the hidden nasopharynx. Misdiagnosis often results from a lack of knowledge about the early signs and symptoms of nasopharyngeal carcinoma. Objective: To know the characteristic of NPC patients in Sanglah General Hospital Denpasar period 2016-2020. Methods: This study used a descriptive research design with a cross sectional design with 602 sample, by taking secondary data from the medical records of patients with NPC who were treated at the ENT-KL polyclinic of Sanglah General Hospital Denpasar for the period 2016-2020. Results: Distribution NPC patients based on gender, the most in male group compare to the female (68.44%: 31.56%). the largest age group was in the 41-50 years group as many as 204 people or 33.89%. The most clinical stage group of NPC patients is stage IVA as many as 301 people (50%) with the histopathological type group of undifferentiated carcinomas compare to the other type groups (89.87%). Conclusion: This study found that NPC is more commonly found in males with the majority aged 41-50 years, most commonly found at an advanced stage, was stage IV A with the most histopathological type is undifferentiated carcinoma.

Profile of Nasopharyngeal Carcinoma in Dr. Wahidin Sudirohusodo Hospital Makassar 2011 – 2021

“…The characteristic of the gender in this study is 70.3 % were male, similar to Asnir et al (2020) studies which reported that most sufferers of NPC are men (69.3 %). Saraswati et al (2019) also reported that the highest gender was found in the male gender as many as 75 people (65.79 %) (1,9). Besides that, based on GLOBOCAN (2020), it was reported that in Indonesia, NPC occurs 5.6 times greater in men than women and is the 5th highest cancer in men with a total case of 10.7/100 000 population and women 3.00/100 000 population (4).…”

“…The malignancy is manifested with various nonspecific signs and symptoms, and despite its high incidence, general practitioners' awareness of NPC is inadequate, potentially leading to many late or missed diagnoses, so they come to health services at an advanced stage (7,8). Saraswati et al (2019) reported that the incidence of NPC in Sanglah Hospital Denpasar increased every year and is more often known in the advanced stage (9). Hibatullah et al (2021) reported that the characteristics found in NPC patients are caused by non-specific symptoms so they come to health services at an advanced stage (8).…”