Characteristics and Outcome for Very Elderly Patients (≥ 80 years) Admitted to a Respiratory Care Center in Taiwan

Su, Jian; Lin, Chien-Chou; Chen, Shiow-Kwan; Peng, Ming-Jen; Wu, Chien-Lien

doi:10.1016/j.ijge.2012.01.030

Cited by 4 publications

(8 citation statements)

References 24 publications

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“…Few studies have explored very old patients requiring PMV. 36–38 These studies mainly focused on the clinical characteristics, weaning outcomes and long-term outcomes of patients requiring PMV. No study discusses gender differences in long-term survival outcomes.…”

Section: Discussionmentioning

confidence: 99%

Gender Differences in Prolonged Mechanical Ventilation Patients – A Retrospective Observational Study

Huang¹

2022

IJGM

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Background The gender differences in patients requiring prolonged mechanical ventilation are not understood. We investigated the effects of gender differences in terms of age, causes of respiratory failure, discharge status, successful weaning, mortality rate and long-term survival outcomes in patients receiving prolonged mechanical ventilation. Methods We conducted a six-year retrospective study of patients requiring prolonged mechanical ventilation. Survival curves for all patients requiring prolonged mechanical ventilation and those who were very old (aged ≥ 80 years) were compared based on gender. Results Among the 574 patients enrolled. There was no statistically significant difference between male and female patients regarding successful weaning, ventilator dependence, or in-hospital mortality. We gathered long-term follow-up data on 296 patients, including 70 very old male patients and 41 very old female patients. The 6-month, 3-year, and 5-year mortality rates for the 189 male patients were 75.1%, 85.2%, and 89.9%, respectively; the corresponding rates for the 107 female patients were 66.4%, 86.0%, and 88.8%, respectively. There was no statistically significant difference between two groups regarding mortality rates. The five-year survival curve of male patients was similar to that of female patients. The 6-month, 1-year, and 5-year mortality rates for the 70 very old male patients were 90.0%, 95.7%, and 97.1%, respectively; the corresponding rates for the 41 very old female patients were 63.4%, 90.2%, and 95.1%, respectively. There was a statistically significant difference between very old male and very old female patients in the 6-month mortality rate and the five-year survival curve. Conclusion There were no gender differences in weaning status, ventilator dependence, in-hospital mortality, or survival outcomes among patients requiring prolonged mechanical ventilation. Among very old patients requiring prolonged mechanical ventilation, the risk of death was 34% lower in very old female patients than in very old male patients for a period of five years.

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Section: Discussionmentioning

confidence: 99%

Gender Differences in Prolonged Mechanical Ventilation Patients – A Retrospective Observational Study

Huang¹

2022

IJGM

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“…The presence of an independent age effect on successful weaning in these seriously ill elderly adults with PMV was not found in the multivariable analysis, in agreement with other studies. 12,14 The elderly adults with PMV who were most likely to be weaned had less-impaired respiratory physiology and less-severe illness on LTACH admission, lower burdens of comorbid illnesses, and to a lesser degree, better physical function before ACH admission. These findings were in keeping with those of previous reports.…”

Section: Discussionmentioning

confidence: 99%

“…[5][6][7] Some studies have suggested that age may affect outcomes of individuals requiring PMV, but the extent of this effect has not been studied systematically. [8][9][10][11][12][13][14][15] Thus, the scant information about the effects of age on outcomes of these chronically seriously ill individuals with PMV has limited the information about likely outcomes of older individuals with PMV that could help guide decisions for transfer from acute care hospitals (ACHs) to a long-term care setting. These decisions are anticipated to become increasingly frequent because of projected increases in the numbers of elderly adults with PMV transferable to long-term postacute care settings.…”

mentioning

confidence: 99%

“…Outcome studies of individuals with PMV in long‐term care settings have not focused specifically on the effect of increasing age even though pulmonary function decreases with age . Some studies have suggested that age may affect outcomes of individuals requiring PMV, but the extent of this effect has not been studied systematically . Thus, the scant information about the effects of age on outcomes of these chronically seriously ill individuals with PMV has limited the information about likely outcomes of older individuals with PMV that could help guide decisions for transfer from acute care hospitals (ACHs) to a long‐term care setting.…”

mentioning

confidence: 99%

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Prolonged Mechanical Ventilation in 540 Seriously Ill Older Adults: Effects of Increasing Age on Clinical Outcomes and Survival

Frengley

Sansone

Shakya

et al. 2014

J American Geriatrics Society

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“…In terms of successful weaning, Su et al demonstrated that patients requiring PMV aged ≥80 years have a lower rate of successful weaning and there was a trend towards successful weaning related to age group [8]. Lin et al reported that the failed weaning rate showed no difference based on the patient's age [9].…”

Section: Clinical Variables Between Patients Requiring Pmv Aged <65 Y...mentioning

confidence: 99%

The Age of Older Patients Requiring Prolonged Mechanical Ventilation Is Not the Sole Determinant of Their Long-Term Survival

Huang

2024

Medicina

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Background and Objectives: There are few data on the effects of prolonged mechanical ventilation on elderly patients. Our objective is to investigate the effects of prolonged mechanical ventilation on older patients’ successful weaning and long-term survival. Methods: We examined how aging affected the course and results of elderly patients on prolonged mechanical ventilation by contrasting five age groups. Age, sex, cause of acute respiratory failure, comorbidities, discharge status, weaning status, and long-term survival outcomes were among the information we gathered. Results: Patients on prolonged mechanical ventilation who had undergone tracheostomy and had been successfully weaned had a greater one-year survival rate. The 1-year survival rate was poorer for older patients with four or more comorbidities. Regarding the 5-year survival rate, the risk of death was 45% lower in the successfully weaned patients than in the unsuccessfully weaned patients. The risk of death was 46% lower in patients undergoing tracheostomy than in those not undergoing tracheostomy. Older prolonged mechanical ventilation (PMV) patients with four or more comorbidities had an increased risk of death. Conclusions: When it comes to elderly patients on prolonged mechanical ventilation, there are other factors in addition to age that influence long-term survival. Long-term survival is likewise linked to successful weaning and undergoing tracheostomy.

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Characteristics and Outcome for Very Elderly Patients (≥ 80 years) Admitted to a Respiratory Care Center in Taiwan

Cited by 4 publications

References 24 publications

Gender Differences in Prolonged Mechanical Ventilation Patients – A Retrospective Observational Study

Gender Differences in Prolonged Mechanical Ventilation Patients – A Retrospective Observational Study

Prolonged Mechanical Ventilation in 540 Seriously Ill Older Adults: Effects of Increasing Age on Clinical Outcomes and Survival

The Age of Older Patients Requiring Prolonged Mechanical Ventilation Is Not the Sole Determinant of Their Long-Term Survival

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