Characteristics and outcomes of colorectal cancer surgery by age in a tertiary center in Korea: a retrospective review

Abstract

Purpose: Colorectal cancer (CRC) occurs in all age groups, and the application of treatment may vary according to age. The study was designed to identify the characteristics of CRC by age.Methods: A total of 4,326 patients undergoing primary resection for CRC from September 2006 to July 2019 were reviewed. Patient and tumor characteristics, operative and postoperative data, and oncologic outcome were comparedResults: Patients aged 60 to 69 years comprised the largest age group (29.7%), followed by those aged 50 to 59 and 70 to 79 (24.5% and 23.9%, respectively). Rectal cancer was common in all age groups, but right-sided colon cancer tended to be more frequent in older patients. In very elderly patients, there were significant numbers of emergency surgeries, and the frequencies of open surgery and permanent stoma were greater. In contrast, total abdominal colectomy or total proctocolectomy was performed frequently in patients in their teens and twenties. The elderly patients showed more advanced tumor stages and postoperative ileus. The incidence of adjuvant treatment was low in elderly patients, who also had shorter follow-up periods. Overall survival was reduced in older patients with stages 0 to 3 CRC (P<0.001), but disease-free survival did not differ by age (P=0.391).Conclusion: CRC screening at an earlier age than is currently undertaken may be necessary in Korea. In addition, improved surgical and oncological outcomes can be achieved through active treatment of the growing number of elderly CRC patients.

Influence of additional prophylactic oral antibiotics during mechanical bowel preparation on surgical site infection in patients receiving colorectal surgery

“…Open surgery was also found to be a risk factor for SSI in colorectal surgery in this study, in line with the results of other studies; when open and laparoscopic approaches were compared, a notable reduction in SSI was observed when the laparoscopic approach was employed. [27][28][29] In the laparoscopic approach, not only minimal incision but also the use of a wound protector appears to be effective in reducing SSI, and wound protector use is advocated even in open incision surgeries. 30,31 Although some SSI bundles include a wound protector, it cannot be used for the open approach in Korea, because the Korean insurance system does not cover the cost.…”

Influence of the COVID-19 Pandemic on the Treatment Patterns and Outcomes of Colorectal Cancer

“…To determine whether the COVID-19 pandemic has compromised the long-term oncologic outcomes of colorectal cancer, we must await their long-term reports. Other factors, such as the number of harvested lymph nodes, lymphatic invasion, vascular invasion, perineural invasion, and preoperative obstruction, may also be associated with oncologic outcomes [13,39,50] in addition to the pathologic stage. However, many studies have not reported these variables.…”

Recent Advance in the Surgical Treatment of Metastatic Colorectal Cancer-An English Version

“…Colorectal cancer (CRC) is the third most common cancer type and the second cause of cancer-related mortality in the analysis of global cancer statistics [1]. The overall survival of patients with CRC has improved with the development of multimodal treatments and new chemotherapeutic drugs [2][3][4]. In an analysis of the Surveillance, Epidemiology, and End Results (SEER) database from 2010 to 2019, ageadjusted rates for new CRC declined by 1.8% annually, whereas the 5-year survival rate showed a gradual increase [5].…”