Characteristics and Risk Factors of Hospitalized and Nonhospitalized COVID-19 Patients, Atlanta, Georgia, USA, March–April 2020

Pettrone, Kristen; Burnett, Eleanor; Link‐Gelles, Ruth; Haight, Sarah C.; Schrodt, Caroline A.; England, Lucinda J.; Gomes, Danica; Shamout, Mays; O’Laughlin, Kevin; Kimball, Anne; Blau, Erin F.; Ladva, Chandresh N; Szablewski, Christine M.; Tobin-D’Angelo, Melissa; Oosmanally, Nadine; Drenzek, Cherie; Browning, Sean; Silva, Juliana da; Gold, Jeremy A W; Jackson, Brendan R; Morris, Sapna Bamrah; Natarajan, Pavithra; Fanfair, Robyn Neblett; Patel, Priti R.; Rogers-Brown, Jessica; Rossow, John; Wong, Karen K.; Murphy, David J.; Blum, James M.; Hollberg, Julie; Lefkove, Benjamin; Brown, Frank; Shimabukuro, Tom T.; Midgley, Claire M; Tate, Jacqueline E.; Killerby, Marie E.

doi:10.3201/eid2704.204709

Cited by 13 publications

(10 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…An important finding was the different features between patients presenting with influenza and those with COVID-19: COVID-19 patients were older and more likely to be male, which is in line with risk factors published previously [ 30 , 31 , 32 ]. A higher percentage was admitted from other hospitals.…”

Section: Discussionsupporting

confidence: 88%

Characteristics of Critically Ill Patients with COVID-19 Compared to Patients with Influenza—A Single Center Experience

Herbstreit

Overbeck

Berger

et al. 2021

JCM

View full text Add to dashboard Cite

Infections with SARS-CoV-2 spread worldwide early in 2020. In previous winters, we had been treating patients with seasonal influenza. While creating a larger impact on the health care systems, comparisons regarding the intensive care unit (ICU) courses of both diseases are lacking. We compared patients with influenza and SARS-CoV-2 infections treated at a tertiary care facility offering treatment for acute respiratory distress syndrome (ARDS) and being a high-volume facility for extracorporeal membrane oxygenation (ECMO). Patients with COVID-19 during the first wave of the pandemic (n = 64) were compared to 64 patients with severe influenza from 2016 to 2020 at our ICU. All patients were treated using a standardized protocol. ECMO was used in cases of severe ARDS. Both groups had similar comorbidities. Time in ICU and mortality were not significantly different, yet mortality with ECMO was high amongst COVID-19 patients with approximately two-thirds not surviving. This is in contrast to a mortality of less than 40% in influenza patients with ECMO. Mortality was higher than estimated by SAPSII score on admission in both groups. Patients with COVID-19 were more likely to be male and non-smokers than those with influenza. The outcomes for patients with severe disease were similar. The study helps to understand similarities and differences between patients treated for severe influenza infections and COVID-19.

show abstract

Section: Discussionsupporting

confidence: 88%

Characteristics of Critically Ill Patients with COVID-19 Compared to Patients with Influenza—A Single Center Experience

Herbstreit

Overbeck

Berger

et al. 2021

JCM

View full text Add to dashboard Cite

show abstract

“…While there are numerous studies examining the clinical course of patients with COVID-19 requiring hospitalization or critical care, 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 there is limited data describing the disease course in the outpatient population despite the fact that most patients with COVID-19 do not require hospitalization. 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 Older age and the presence of specific medical conditions have previously been associated with illness severity among adults hospitalized with COVID-19. 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 Both age and specific medical conditions have been associated with greater susceptibility to the disease and prolonged illness in outpatient populations, although data supporting these findings are limited.…”

Section: Introductionmentioning

confidence: 99%

“… 15 , 35 , 36 , 37 Several studies have described symptoms at presentation and used pre-specified time periods to check patient symptoms. 15 , 18 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 However, to our knowledge, only two studies have followed subjects to symptom resolution, 20 , 21 and no study has tested if symptoms at disease onset are predictive of symptom duration.…”

Section: Introductionmentioning

confidence: 99%

Clinical characteristics and symptom duration among outpatients with COVID-19

Hunter

Lee

Hyman

et al. 2022

American Journal of Infection Control

View full text Add to dashboard Cite

“…Older age, male sex, comorbidities, and preadmission treatment with insulin were also reported as risk factors for poor prognosis after COVID-19 infection (56,105,108,(117)(118)(119)(120)(121)(122). Confirmatory were the results of a meta-analysis including 22 studies (123).…”

Section: The Role Of Glucose-lowering Drugs On Disease Severitymentioning

confidence: 89%

The Role of Diabetes and Hyperglycemia on COVID-19 Infection Course—A Narrative Review

Tzeravini¹,

Stratigakos²,

Siafarikas³

et al. 2022

Front. Clin. Diabetes Healthc.

View full text Add to dashboard Cite

It was previously reported that subjects with diabetes mellitus (DM) are more vulnerable to several bacterial or viral infections. In the era of coronavirus disease 2019 (COVID-19) pandemic, it is reasonable to wonder whether DM is a risk factor for COVID-19 infection, too. It is not yet clear whether DM increases the risk for contracting COVID-19 infection or not. However, patients with DM when infected are more likely to develop severe or even fatal COVID-19 disease course than patients without DM. Certain characteristics of DM patients may also deteriorate prognosis. On the other hand, hyperglycemia per se is related to unfavorable outcomes, and the risk may be higher for COVID-19 subjects without pre-existing DM. In addition, individuals with DM may experience prolonged symptoms, need readmission, or develop complications such as mucormycosis long after recovery from COVID-19; close follow-up is hence necessary in some selected cases. We here present a narrative review of the literature in order to set light into the relationship between COVID-19 infection and DM/hyperglycemia.

show abstract

Characteristics and Risk Factors of Hospitalized and Nonhospitalized COVID-19 Patients, Atlanta, Georgia, USA, March–April 2020

Cited by 13 publications

References 12 publications

Characteristics of Critically Ill Patients with COVID-19 Compared to Patients with Influenza—A Single Center Experience

Characteristics of Critically Ill Patients with COVID-19 Compared to Patients with Influenza—A Single Center Experience

Clinical characteristics and symptom duration among outpatients with COVID-19

The Role of Diabetes and Hyperglycemia on COVID-19 Infection Course—A Narrative Review

Contact Info

Product

Resources

About