Characteristics, associations and outcome of partial agenesis of the corpus callosum in the fetus

Volpe, P.; Paladini, D.; Resta, M.; Stanziano, A.; Salvatore, Marco; Quarantelli, Mario; Robertis, V. De; Buonadonna, A.; Caruso, G.; Gentile, Mattia

doi:10.1002/uog.2774

Cited by 123 publications

(149 citation statements)

References 27 publications

Supporting

Mentioning

130

Contrasting

Unclassified

Order By: Relevance

“…The formation of the CC starts with the development of the genu; the body and splenium develop at a later stage. If the normal developmental process is disturbed, the CC may be completely or partially absent (PACC) (hypogenetic) (Barkovich, 2000(Barkovich, , 2002Volpe et al, 2006;Raybaud and Girard, 2005). As the developmental process starts from the anterior part and progresses front to rear, when the CC is hypogenetic it is usually the posterior portion that gets affected (the posterior body and the splenium).…”

Section: Agenesis Of the Corpus Callosummentioning

confidence: 99%

“…The latter mechanism usually occurs in association with hypoxic ischemic injury and infectious causes (Volpe et al, 2006).…”

Section: Agenesis Of the Corpus Callosummentioning

confidence: 99%

“…In this case, the sonographic findings are more subtle than those associated with the complete form. When the CC is hypogenetic, it is usually the posterior portion that is affected (the posterior body and the splenium) ( Figure 7); in this situation, the CSP is present (Volpe et al, 2006), and often the only indirect sonographic sign is a mild colpocephaly. Sometimes, the indirect signs of PACC may also be completely absent (Volpe et al, 2006).…”

Section: Sonographic Findingsmentioning

confidence: 99%

“…When the CC is hypogenetic, it is usually the posterior portion that is affected (the posterior body and the splenium) ( Figure 7); in this situation, the CSP is present (Volpe et al, 2006), and often the only indirect sonographic sign is a mild colpocephaly. Sometimes, the indirect signs of PACC may also be completely absent (Volpe et al, 2006). A sagittal view is the only way to reach the diagnosis, visualizing a small CC that is lacking the posterior part and only partially surrounds the third ventricle ( Figure 7).…”

Section: Sonographic Findingsmentioning

confidence: 99%

See 3 more Smart Citations

Disorders of prosencephalic development

Volpe¹,

Campobasso²,

Robertis³

et al. 2009

Prenatal Diagnosis

Self Cite

107

View full text Add to dashboard Cite

Abnormal ventral induction may result in disorders of formation, cleavage, and midline development of prosencephalic structures. Holoprosencephaly is a developmental field defect of impaired cleavage of prosencephalon. The most widely accepted classification of holoprosencephaly recognizes three major varieties: the alobar, semilobar and lobar types, according to the severity of the malformation. The brain malformations, characterized by the fusion of the cerebral hemisphere along the midline are commonly associated with facial anomalies.Corpus callosum agenesis and septo-optic dysplasia are disorders of prosencephalic midline development, and usually have less severe presentations but still, affected subjects may suffer from neurodevelopmental retardation, and/or endocrinologic and visual disorders.In this article we report an up-to-date of pathogenesis, prenatal sonographic findings, differential diagnosis and prognosis of the aforementioned anomalies.

show abstract

Section: Agenesis Of the Corpus Callosummentioning

confidence: 99%

“…The latter mechanism usually occurs in association with hypoxic ischemic injury and infectious causes (Volpe et al, 2006).…”

Section: Agenesis Of the Corpus Callosummentioning

confidence: 99%

Section: Sonographic Findingsmentioning

confidence: 99%

Section: Sonographic Findingsmentioning

confidence: 99%

See 2 more Smart Citations

Disorders of prosencephalic development

Volpe¹,

Campobasso²,

Robertis³

et al. 2009

Prenatal Diagnosis

Self Cite

107

View full text Add to dashboard Cite

show abstract

“…A incidência de anormalidades do CC (hipoplasia, agenesia total e parcial) varia de 0,3 a 0,7% 4 . O quadro clínico que indique anomalia do CC não é específico, sendo o diagnóstico feito, na maior parte das vezes, em exames ocasionais.…”

Section: Introductionunclassified

Avaliação do comprimento e área do corpo caloso fetal por meio da ultrassonografia tridimensional

Visentainer

Júnior

Rôlo

et al. 2010

Rev. Bras. Ginecol. Obstet.

View full text Add to dashboard Cite

Artigo originalResumo OBJETIVO: determinar os valores de referência para o comprimento e a área do corpo caloso fetal entre a 20 a e 33 a semanas de gestação por meio da ultrassonografia tridimensional (US3D). MÉTODOS: foi realizado um estudo do tipo corte transversal com 70 gestantes normais entre a 20 a e 33 a semanas de gestação. Utilizou-se um aparelho da marca Accuvix XQ, equipado com transdutor convexo volumétrico (3 a 5 MHz). Para a obtenção do corpo caloso fetal, foi utilizado um plano transfrontal, com a sutura metópica como janela acústica. Para o cálculo do comprimento, utilizou-se a distância entre os pontos médios dos polos proximal e distal do corpo caloso. Para o cálculo da área, a delimitação manual da superfície externa do corpo caloso foi realizada. Para o comprimento e a área do corpo caloso, foram calculadas: as médias, as medianas, os desvios padrão e os valores máximo e mínimo. Para a correlação da área e do comprimento do corpo caloso com a idade gestacional e o diâmetro biparietal foram criados diagramas de dispersão, sendo a qualidade dos ajustes verificada pelo coeficiente de determinação (R 2 ). Para a variabilidade intraobservador, utilizou-se o coeficiente de correlação intraclasse (CCI). RESULTADOS: a média do comprimento do corpo caloso variou de 21,7 mm (18,6 -25,2 mm) a 38,7 mm (32,6 -43,3 mm) entre a 20 a e 33 a semanas, respectivamente. A média da área do corpo caloso variou de 55,2 mm 2 (41,0 -80,0 mm 2 ) a 142,2 mm 2 (114,0 -160,0 mm 2 ) entre a 20 a e 33 a semanas, respectivamente. O comprimento e a área do corpo caloso foram fortemente correlacionados com a idade gestacional (R 2 = 0,7 e 0,7, respectivamente) e com o diâmetro biparietal (R 2 = 0,7 e 0,6, respectivamente). A variabilidade intraobservador foi adequada com CCI = 0,9 e 0,9 para o comprimento e área, respectivamente. CONCLUSÕES: valores de referência para o comprimento e área do corpo caloso fetal entre a 20 a e 33 a semanas foram determinados. A variabilidade intraobservador foi adequada.Abstract PURPOSE: to establish reference values for the length and area of the fetal corpus callosum between the 20 th and 33 rd weeks of gestation using three-dimensional ultrasound (3DUS). METHODS: this cross-sectional study involved 70 normal pregnancies with gestational age between 20 and 33 weeks. An Accuvix XQ instrument with a convex volumetric transducer (3 to 5 MHz) was used. To assess the corpus callosum, a transfrontal plane was obtained using the metopic suture as an acoustic window. Length was obtained by measuring the distance between the proximal and distal extremities of the corpus callosum. Area was obtained by manual tracing of the external corpus callosum surface. The means, medians, standard deviations, and maximum and minimum values were calculated for the corpus callosum length and area. Scatter graphs were created to analyze the correlation between corpus callosum length and area and gestational age and biparietal diameter, the quality adjustments was verified according to the determination coefficient (R...

show abstract

Prenatal Diagnosis and Management of Abnormal Fetal Development with Emphasis on the Third Trimester of Pregnancy

Wladimiroff

Cohen–Overbeek

2009

Genetic Disorders and the Fetus

View full text Add to dashboard Cite

Characteristics, associations and outcome of partial agenesis of the corpus callosum in the fetus

Cited by 123 publications

References 27 publications

Disorders of prosencephalic development

Disorders of prosencephalic development

Avaliação do comprimento e área do corpo caloso fetal por meio da ultrassonografia tridimensional

Prenatal Diagnosis and Management of Abnormal Fetal Development with Emphasis on the Third Trimester of Pregnancy

Contact Info

Product

Resources

About