Characteristics, diagnosis, and treatment modality of pediatric patients with cystic echinococcosis: a single centre experience

Kaman, Ayşe; Tanır, Gönül; Çakmakçı, Emin; Demır, Pervin; Öz, Fatma Nur; Teke, Türkan Aydın; Metin, Özge; Gayretli-Aydın, Zeynep Gökçe; Karaman, Ayşe

doi:10.24953/turkjped.2019.05.009

Cited by 8 publications

(7 citation statements)

References 11 publications

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“…Results of the present study suggest that exposure to the parasite starts from childhood, and the rate of hospitalization may increase with age. Similar to our findings, Dashti et al [12], Çelebi et al [45], and Kaman et al [46] reported the mean ages of children with CE to be 11.5 ± 6.1 years, 12.4 years, and 10.3 ± 3.5 years, respectively. More than half of our study participants were registered as children aged 11-17 years.…”

Section: Discussionsupporting

confidence: 92%

Cystic Echinococcosis in Hospitalized Children from Western Romania: A 25-Year Retrospective Study

Paduraru,

Lupu,

Popoiu

et al. 2024

Biomedicines

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Cystic echinococcosis (CE) is a cosmopolitan parasitic disease caused by Echinococcus granulosus. We aimed to assess the epidemiological aspects of the disease in hospitalized children from Western Romania, a well-known endemic area for CE. We retrospectively investigated the medical records of children hospitalized between 1998 and 2022. A total of 144 patients were included, and 58.3% were from rural areas. The number of cases increased with age, from 9% in the age group 3–5 years to 59.7% in the age group 11–17 years. The liver was more frequently affected (65.3%), and a significant association between gender and the affected organ was noted; liver cysts were more frequently diagnosed in girls, while lung cysts were recorded mostly in boys. Complications were more frequently reported in patients with pulmonary CE compared to hepatic CE (p = 0.04). Boys had more complications (16/23, 69.6%) compared to girls (7/23, 30.4%) (p = 0.03). A third of the children were hospitalized for more than 14 days, and multiple hospitalizations were recorded in 31.3% of the patients. This paper provides new insights into the epidemiologic features of cystic echinococcosis in children from Western Romania. Our findings indicate that exposure to the parasite starts in childhood, and the rate of hospitalization increases with age. Public health strategies should be implemented and permanently improved in order to lower the prevalence of CE in children.

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Section: Discussionsupporting

confidence: 92%

Cystic Echinococcosis in Hospitalized Children from Western Romania: A 25-Year Retrospective Study

Paduraru,

Lupu,

Popoiu

et al. 2024

Biomedicines

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“…[24] IHA test positivity in combination with abdominal ultrasonography is useful in diagnosing liver hydatid cyst, but thoracic CT is usually required to diagnose hydatid cyst of the lung. [25] In our study, echinococcus IHA was positive in 42.9% of the children. Eosinophilia was reported in 20-34% of hydatid cyst cases.…”

Section: Discussionsupporting

confidence: 48%

Çocuklarda Kistik Ekinokokkoz: On Yıllık Tecrübe ve Rüptüre Olguları Değerlendirmede Hangi Laboratuar Sonucu?

Salman

SALMAN>²,

KART>

et al. 2023

Journal of Contemporary Medicine

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Aim Hydatid disease (Echinococcosis) is a common zoonosis in countries that are involved in livestock such as our country. Our study aims to evaluate pediatric cases with hydatid disease over the last decade in our region and to determine the significance of initial clinical and laboratory findings in distinguishing ruptured hydatid cyst cases. Materials and Methods A retrospective analysis was made on demographic characteristics, presenting symptoms, physical examination, laboratory and radiological findings, and treatments of children with hydatid disease who were treated in our hospital and followed up regularly between January 2011 and December 2020. Results The study sample of 42 cases included 19 (45.2%) girls, with a median age of 125.5 (34-209) months. The most common symptom was abdominal pain (50%), and the most common physical examination finding was decreased breath sounds (23.8%). Thirty-five (83.3%) patients had single organ involvement and 7 (16.7) patients had multiple organ involvement. Cysts were detected in the right lobe of the liver in 24 (75%) of hepatic hydatid cysts and the left lobe in 7 (58.3%) of pulmonary hydatid cysts. The median size of the cysts was 57.5 (12-140) mm. The initial IHA titer, eosinophil count, eosinophil percentage, and sedimentation value were statistically significantly higher in patients with ruptured cysts than in those without rupture (p= 0.002, p= 0.003, p= 0.003, p= 0.02, respectively). Conclusions Initial pathological examination findings and at initial laboratory findings such as high IHA titer, eosinophil count, eosinophil percentage, sedimentation value can be used to distinguish rupture cases.

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“…Studies have also been reported the prevalence of the multiorgan involvement in the paediatric patients as 0%-12.5%. [6][7][8][9][10][11][12] In the literature, paediatric patients with the multiorgan involvement have been reported as case reports. [13][14][15][16][17][18][19][20][21][22][23] All the current cases of multiorgan involvement are presented in Table 3.…”

Section: Discussionmentioning

confidence: 99%

“…However, ≥3 organ involvement is very rare, especially in the paediatric patients. Studies have also been reported the prevalence of the multiorgan involvement in the paediatric patients as 0%–12.5% 6–12 . In the literature, paediatric patients with the multiorgan involvement have been reported as case reports 13–23 .…”

Section: Discussionmentioning

confidence: 99%

Multi‐organ/disseminated echinococcosis in children: Case series and review of the literature

Çay

Alabaz

Gündeşli̇oğlu

et al. 2022

J Paediatrics Child Health

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Aim: Echinococcosis with multi-organ/disseminated involvement is rare in childhood. We aimed to evaluate the clinical and laboratory characteristics and prognosis in paediatric patients with echinococcosis having multiorgan/disseminated involvement. Method: We evaluated retrospectively children with echinococcosis with involvement of three or more organs. Results: Thirteen patients were included in the study. The median age was 120 (range 71-189) months. Three (23%) were diagnosed incidentally. Abdominal pain was seen in 5 (38.4%) patients, vomiting in 4 (30.7%), headache in 3 (23%), cough in 2 (15.3%), groin pain in 1 (7.6%), 1 (7.6%) had jaundice and 1 (7.6%) had fever. The median duration of complaints was 48 (0-140) days. The most common tripartite organ was 38.4% (5/13) liver, lung and spleen. Isolated abdominal dissemination was detected in two patients. Two patients had multi-organ involvement and multiple cysts with dissemination. Cyst rupture was observed in three of the patients; recurrent urinary tract infection, hydroureteronephrosis, secondary peritonitis with intraabdominal abscess, and biliary tract fistula were each observed in one patient. Relapse developed in 3 (23%) patients. Conclusion: Echinococcosis is a very slow growing and complex parasitic disease that affects many organs and tissues. In our study, eosinophilia, recurrence, and complications were seen at a higher rate in paediatric patients with multiorgan involvement, who required repetitive surgeries and long-term medical treatment. However, there are scanty data on risk factors, optimum treatment and prognosis.

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Characteristics, diagnosis, and treatment modality of pediatric patients with cystic echinococcosis: a single centre experience

Cited by 8 publications

References 11 publications

Cystic Echinococcosis in Hospitalized Children from Western Romania: A 25-Year Retrospective Study

Cystic Echinococcosis in Hospitalized Children from Western Romania: A 25-Year Retrospective Study

Çocuklarda Kistik Ekinokokkoz: On Yıllık Tecrübe ve Rüptüre Olguları Değerlendirmede Hangi Laboratuar Sonucu?

Multi‐organ/disseminated echinococcosis in children: Case series and review of the literature

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