Characteristics of chest high resolution computed tomography images of COVID-19: A retrospective study of 46 patients

Lu, Yao; Zhou, Jingru; Mo, Yimei; Song, Shulin; Xue, Wei; Ding, Ke

doi:10.12669/pjms.37.3.3504

Cited by 2 publications

(2 citation statements)

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“…Infected patients examined on X-rays and chest CT imaging showed unilateral or bilateral involvement which was complementary with viral pneumonia, and bilateral multiple lobular and sub- segmental consolidation areas were found in patients hospitalized in the ICU. 24 , 25 In agreement to the above study the same observations were recorded in our study in about 40% of the symptomatic patients.…”

Section: Discussionsupporting

confidence: 93%

Lower mortality rate in health workers and their families infected with COVID-19 associated pneumonia in Quetta, Baluchistan

Aslam¹,

Zehri²,

Mandoklel³

et al. 2021

Pak J Med Sci

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Objectives: A bunch of pneumonia cases in Wuhan, China, was caused by a novel beta-corona virus, (COVID-19) in December 2019 from where it spread rapidly across the globe. The aim of the study was to find out relevant reasons and offered suggestions to reduce the risk of infection and check clinical outcomes of the infected healthcare workers. Methods: This study was conducted in COVID-19 Real Time Polymerase Chain Reaction (RT-PCR) laboratory, Bolan Medical Complex Hospital Quetta, Baluchistan from May to June 2020. Eight hundred (n=800) health workers and their families were included in this study. Data were obtained with standardized data collection forms shared by the WHO. Nasopharyngeal samples were collected following the WHO protocols. RNA was extracted and amplified using real time reverse transcriptase polymerase chain reaction (RT-PCR). Serum ferritin level, C-reactive protein, D-dimer and radiological results of the RT-PCR confirmed individuals were also recorded and analyzed. Results: Among (n=800) health workers and their families 457 (57.1%) were COVID-19 PCR negative, 332 (41.5%) positive and 11 (1.4%) individuals were PCR positive but asymptomatic carriers, 234 (29.5%) were male and 103 (12.9%) were female. Mortality rate in our study was very low, only three patients (0.87%) died of this COVID-19 pneumonia. Conclusion: Our results showed increased rate of positive cases with fortunately lower mortality rate, although this novel pneumonia was associated with acute respiratory distress syndrome ARDS and intensive care unit (ICU) admission. Timely decisions, risk awareness knowledge and supply of necessary equipments are inevitable for the control of such epidemics. doi: https://doi.org/10.12669/pjms.37.7.4060 How to cite this:Aslam M, Zehri MT, Mandoklel H, Kamal R, Din M. Lower mortality rate in health workers and their families infected with COVID-19 associated pneumonia in Quetta, Baluchistan. Pak J Med Sci. 2021;37(7):---------. doi: https://doi.org/10.12669/pjms.37.7.4060 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Section: Discussionsupporting

confidence: 93%

Lower mortality rate in health workers and their families infected with COVID-19 associated pneumonia in Quetta, Baluchistan

Aslam¹,

Zehri²,

Mandoklel³

et al. 2021

Pak J Med Sci

View full text Add to dashboard Cite

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“… 14 Studies also show that consolidations (including multifocal, patchy or segmental consolidation) are usually present in NCIP patients, and may be associated with the progression of the disease. 15 , 16 There were only 4 patients with GGO and consolidation in our study, which suggest that most Hengyang patients were in the very early stages of the disease. Importantly, the radiological finding like GGO and consolidation are also found on CT images of H1N1-infected patients.…”

Section: Discussionmentioning

confidence: 52%

Diagnostic value of neutrophil-to-lymphocyte, lymphocyte-to-monocyte and platelet-to-lymphocyte ratio among patients with COVID-19 pneumonia: A retrospective study

Long¹,

Zhang²,

Duan

2022

Pak J Med Sci

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Objectives: Our study was aimed to investigate the clinical characteristics of the patients with COVID-19 pneumonia and research new diagnostic methods for the disease. Methods: In this retrospective study, medical records of 46 novel coronavirus-infected pneumonia (NCIP) patients and 30 healthy individuals in the two multiple hospitals from January 2020 to March 2020 were studied. Clinical characteristics, chest computed tomographic (CT) scans, medicine treatment and laboratory information were collected and retrospectively analyzed. Neutrophil-to-lymphocyte ratio (NLR), lymphocyte-to-monocyte ratio (LMR) and platelet-to-lymphocyte ratio (PLR) were evaluated. Results: The main symptoms of the patients with NCIP were fever (100%), cough (82.6%), anorexia (37%), expectoration (34.8%) and fatigue (21.7%), dyspnea (15.2%). Ground glass opacity (GGO) with patch shadow was the main observation of the CT imaging (43.4%), followed by GGO (21.7%), patch shadow (19.5%), GGO with consolidation (8.7%) and GGO with reticular pattern (2.1%). The median white blood cell (WBC) count, lymphocyte count, platelet, and lymphocyte-monocyte ratio (LMR) in NCIP group were all significantly lower than in control group (p<0.001, for all comparisons), while the median neutrophil-monocyte ratio (NLR) and platelets-monocyte ratio (PLR) were both significantly higher (p<0.001, for both comparisons). Median WBC count, lymphocyte count, and platelet count on discharge were significantly higher than on admission (p<0.05). Median PLR was significantly lower two weeks after discharge (p<0.001), while NLR remained the same. The area under the curve (AUC) value of WBC, lymphocyte and platelet counts, NLR, LMR and PLR were 0.766, 0.931, 0.655, 0.780, 0.847 and 0.845, respectively. Early stages of the disease were associated with quick changes in WBC, lymphocyte, and platelet levels. However, NLR did not recover even two weeks after the discharge. Conclusion: Changes in WBC, lymphocyte, and platelet counts, as well as NLR, LMR and PLR are strongly associated with COVID-19 pneumonia. Monitoring blood markers may assist in evaluating the progression of the disease doi: https://doi.org/10.12669/pjms.38.5.5798 How to cite this:Long X, Zhang T, Duan S. Diagnostic value of neutrophil-to-lymphocyte, lymphocyte-to-monocyte and platelet-to-lymphocyte ratio among patients with COVID-19 pneumonia: A retrospective study. Pak J Med Sci. 2022;38(5):---------. doi: https://doi.org/10.12669/pjms.38.5.5798 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Characteristics of chest high resolution computed tomography images of COVID-19: A retrospective study of 46 patients

Cited by 2 publications

References 20 publications

Lower mortality rate in health workers and their families infected with COVID-19 associated pneumonia in Quetta, Baluchistan

Lower mortality rate in health workers and their families infected with COVID-19 associated pneumonia in Quetta, Baluchistan

Diagnostic value of neutrophil-to-lymphocyte, lymphocyte-to-monocyte and platelet-to-lymphocyte ratio among patients with COVID-19 pneumonia: A retrospective study

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