Characteristics of corneal high-order aberrations in adolescents with mild to moderate myopia

Zhang, Xu; Ma, Jinhui; Xi, Xin; Guan, Lin

doi:10.1186/s12886-020-01727-z

Cited by 11 publications

(6 citation statements)

References 27 publications

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“…K2 was mainly associated with spherical aberration and astigmatism before surgery, and was associated with trefoil at 30° after surgery. Zhang et al found that corneal spherical aberrations were correlated with K1 and K2 in myopia (18), which is consistent with our results. Rm is the mean radius of the curvature of the cornea.…”

Section: Discussionsupporting

confidence: 93%

Factors associated with corneal high-order aberrations before and after femtosecond laser-assisted in situ keratomileusis

Zeng¹,

Lan²,

Zhu³

et al. 2021

Ann Transl Med

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Background: Corneal high-order aberrations (HOAs) are related to visual quality. However, the factors associated with corneal HOAs before and after femtosecond laser-assisted in situ keratomileusis (FS-LASIK)have not yet been elucidated. The aim of this study is to observe the factors related to corneal HOAs before and after FS-LASIK.Methods: Prospective observational study was designed to measure corneal HOAs in 149 eyes of 75 patients before and 6 months after FS-LASIK. The relationship between spherical diopter and corneal parameters, including K1 and K2 (horizontal and vertical refractive power of the cornea, respectively), the aspheric characteristics of the cornea (Q), mean radius of the curvature of the cornea (Rm), and central corneal thickness (CCT), with corneal HOAs were analyzed. Results:The spherical diopter was correlated with trefoil at 30° before surgery and with vertical coma, four-order astigmatism at 0°, trefoil at 30°, spherical aberration, and six-order spherical aberration after surgery (P<0.05). CCT was correlated with vertical coma, four-order astigmatism at 0°, trefoil at 30°, and sixorder spherical aberration after surgery (P<0.05). K1 was correlated with spherical aberration and six-order astigmatism at 0° before surgery (P<0.05). K2 was correlated with spherical aberration, six-order astigmatism at 45°, astigmatism at 0°, six-order astigmatism at 0° before surgery, and trefoil at 30° after surgery (P<0.05).Q was correlated with spherical aberration, six-order spherical aberration, and six-order astigmatism at 45° (P<0.05). Rm was correlated with six-order astigmatism at 0°, spherical aberration, six-order astigmatism at 45° before surgery, and astigmatism at 0° after surgery (P<0.05) Conclusions: Corneal parameters and spherical diopter are related to the HOAs of the cornea before and after FS-LASIK.

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Section: Discussionsupporting

confidence: 93%

Factors associated with corneal high-order aberrations before and after femtosecond laser-assisted in situ keratomileusis

Zeng¹,

Lan²,

Zhu³

et al. 2021

Ann Transl Med

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“…Mohammadpour et al reported an increase in HOAs, correlating with an increase of ocular astigmatism (22). Similarly, Zhang et al found that an increase in astigmatism was associated with an increase in coma, trefoil and total HOAs (23). These ndings were similar to our results, where we found that total HOAs, coma and trefoil were at their highest levels in the astigmatism group.…”

Section: Discussionsupporting

confidence: 90%

Corneal higher order aberrations by Sirius topography and their relation to different refractive errors

Salman

Kailani

Ghabra

et al. 2022

Preprint

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Purpose: to compare the root mean square (RMS) of anterior corneal higher-order aberrations (HOAs) in patients with refractive errors.Methods: This retrospective observational study was conducted at Department of Ophthalmology, Tishreen University Hospital, Latakia, Syria. The eyes were divided into four groups based on refractive error: mild-to-moderate myopia, hypermetropia, myopic astigmatism, and emmetropic eyes as controls. The following anterior corneal HOAs were evaluated using the Scheimpflug-Placido Sirius (CSO, Italy) topographer over 6 mm pupil: Root mean square (RMS) total corneal HOAs, RMS trefoil, RMS coma and RMS spherical aberrations. Results: RMS values of total HOAs, trefoil and coma showed a statistically significant difference in all four groups (P < 0.05, all). They were lowest in the control group (0.18± 0.09, 011± 0.08 and 0.09± 0.08 μm, respectively) and highest in the myopic astigmatism group (0.31± 0.16, 0.15± 0.12, 0.17± 0.14 μm, respectively). RMS spherical aberration was lowest in the astigmatism group (0.00± 0.16 μm) with a statistically significant difference from that in the control groups (0.05± 0.07 μm, P = 0.049).Conclusion: The mean RMS values of total HOAs, trefoil and coma were highest in the astigmatism group and lowest in the control group. However, spherical aberration was minimal in the astigmatism group.

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“…Currently all the existing theoretical hypotheses that the ortho-k lens controls myopia progression, such as the retinal peripheral defocus theory ( Gardner et al, 2015 ; Smith et al, 2020 ), the aberration theory ( Hiraoka et al, 2015 ; Zhang X. et al, 2020 ; Lau et al, 2020 ), and the accommodation theory ( Batres et al, 2020 ; Song et al, 2021 ), are based on the change of the corneal shape or reduction of the refractive error after ortho-k lens wear. The biomechanical interaction between the lens and the cornea or the entire eyeball is vitally important in the course of ortho-k treatment.…”

Section: Discussionmentioning

confidence: 99%

The Biomechanical Response of the Cornea in Orthokeratology

Fang

et al. 2021

Front. Bioeng. Biotechnol.

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Orthokeratology has been widely used to control myopia, but the mechanism is still unknown. To further investigate the underlying mechanism of corneal reshaping using orthokeratology lenses via the finite element method, numerical models with different corneal curvatures, corneal thicknesses, and myopia reduction degrees had been developed and validated to simulate the corneal response and quantify the changes in maximum stress in the central and peripheral corneal areas during orthokeratology. The influence of the factors on corneal response had been analyzed by using median quantile regression. A partial eta squared value in analysis of variance models was established to compare the effect size of these factors. The results showed central and peripheral corneal stress responses changed significantly with increased myopia reduction, corneal curvature, and corneal thickness. The target myopia reduction had the greatest effect on the central corneal stress value (partial eta square = 0.9382), followed by corneal curvature (partial eta square = 0.5650) and corneal thickness (partial eta square = 0.1975). The corneal curvature had the greatest effect on the peripheral corneal stress value (partial eta square = 0.5220), followed by myopia reduction (partial eta square = 0.2375) and corneal thickness (partial eta square = 0.1972). In summary, the biomechanical response of the cornea varies significantly with the change in corneal conditions and lens designs. Therefore, the orthokeratology lens design and the lens fitting process should be taken into consideration in clinical practice, especially for patients with high myopia and steep corneas.

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Characteristics of corneal high-order aberrations in adolescents with mild to moderate myopia

Cited by 11 publications

References 27 publications

Factors associated with corneal high-order aberrations before and after femtosecond laser-assisted in situ keratomileusis

Factors associated with corneal high-order aberrations before and after femtosecond laser-assisted in situ keratomileusis

Corneal higher order aberrations by Sirius topography and their relation to different refractive errors

The Biomechanical Response of the Cornea in Orthokeratology

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