Characteristics of COVID‒19 in hemodialysis patients

Abstract

Keywords： COVID 19, hemodialysis, D dimer, PCR test 〈Abstract〉 ［Objective］ Little is known about the clinical courses of hemodialysis patients with COVID 19. We examined the characteristics of COVID 19 in hemodialysis patients. ［Materials and Methods］ We enrolled 33 hemodialysis patients with COVID 19 and 174 non hemodialysis patients with COVID 19 who were admitted to our hospital in this study. We compared the clinical course of COVID 19 between the hemodialysis and non hemodialysis patients. Among the hemodialysis patients with COVID 19, we also compared the laboratory data of the severe and non severe groups. ［Results］ While 44.4％ of the hemodialysis patients were treated with steroids, only 13.2％ of the non hemodialysis patients received steroid treatment (p ＜0.001). Among the patients who were not treated with steroids, it took 10.3±3.2 days for fevers to resolve in the hemodialysis patients, which was significantly longer than in the non hemodialysis patients (8.0±3.6 days, p＝0.034). In addition, it took 31.1±7.3 days for the hemodialysis patients to become PCR negative, which was significantly longer than it took in the non hemodialysis patients (21.7±4.4 days, p＝0.016). The mortality rate among the dialysis patients was 12.1％, whereas none of the non hemodialysis patients died. The hemodialysis patients had a significantly worse prognosis than the non hemodialysis patients (p ＜0.001). Of the 4 deaths, thrombosis was suspected to be the cause of death in 2 cases. In a comparison between the severe and non severe cases, high C reactive protein (CRP) and D dimer levels and leukocyte counts and low lymphocyte ratios were seen in the severe group. ［Conclusion］ Among COVID 19 patients, more hemodialysis patients than non hemodialysis patients required

Characteristics of hemodialysis patient with critical COVID‐19

“…In the hemodialysis patients, a longer time was required for the fever to resolve and the RT‐PCT test to become negative, and the prognosis was poor. Careful monitoring for potential progression to critical disease may be necessary in patients with an elevated WBC count, serum CRP, d ‐dimer levels and a decreased lymphocyte count [11]. In the present report, we enrolled a relatively large number of patients and classified the patients in greater detail.…”