Characteristics of factors for decreased lung function in elderly patients with type 2 diabetes

Ishii, Masaki; Yamaguchi, Yasuhiro; Hamaya, Hironobu; Ogawa, Sumito; Imura, Mitsuo; Akishita, Masahiro

doi:10.1038/s41598-019-56759-3

Cited by 7 publications

(6 citation statements)

References 30 publications

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“…Evaluation of the nutrition status with BMI was essential in prognosis of other pulmonary disease patients including the chronic obstructive pulmonary disease and the nosocomial infection. (26)(27)(28)(29) The present study suggested that the gender of females might be risk for the prolonged hospitalization. The reason why the hospitalization stay tended to be long in the aged females pneumonia patients was not clear, (30) as the number of the patients with good performance status (0 + 1) was not different between males (14 cases) and females (13 cases) and there was no significance difference between the genders regarding the other factors evaluated in the present study.…”

Section: Discussionmentioning

confidence: 53%

Risk for prolonged hospitalization and mortality in aged community acquired pneumonia patients: a retrospective study in Japan

Matsuo

Takamori

Kawaura

et al. 2020

J. Clin. Biochem. Nutr.

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The present study aimed to reveal; i) risk for prolonged hospital ization and mortality in aged community acquired pneumonia patients, and ii) whether swallowing ability was related to re hospitalization. The present retrospective study included 92 patients older than 75 years hospitalized with community acquired pneumonia in Takagi hospital between April 2017 and March 2018. The patients were classified into 3 groups; discharged within 17 days (group I): hospitalized more than 18 days (group II): died during the hospitalization (group III). Swallowing ability was evaluated if available. Univariate analysis indicated males and body mass index (BMI) in group I (n = 24) were higher than group II (n = 46). Group III (n = 22) had low serum albumin, low BMI, and severe disease progression compared with group I. Multivariate analysis demonstrated that group II BMI was lower than group I [odds ratio (OR) = 1.18, p = 0.042]. Group III had lower serum albumin level compared with group I (OR = 81.01, p = 0.025). Diabetes mellitus (p = 0.009), but not swallowing disability, was risk for readmission. Malnutrition represented by low albumin enhanced mortality rate in the pneumonia patients, and low BMI and diabetes mellitus might increase the pneumonia risk.

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Section: Discussionmentioning

confidence: 53%

Risk for prolonged hospitalization and mortality in aged community acquired pneumonia patients: a retrospective study in Japan

Matsuo

Takamori

Kawaura

et al. 2020

J. Clin. Biochem. Nutr.

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“…In addition, there is evidence that the concentrations of insulin, C-peptide, leptin and the glucose/insulin ratio are associated with recurrent wheezing in preschool children [ 36 ]. A number of studies indicate an increase in the level of C-peptide in patients with COPD [ 37 , 38 , 39 ]. At the same time, none of the studies evaluated the level of C-peptide and insulin in individuals with combined pathology of AO and bronchitis.…”

Section: Discussionmentioning

confidence: 99%

Blood Adipokines/Cytokines in Young People with Chronic Bronchitis and Abdominal Obesity

et al. 2022

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The pathogenesis of the development of chronic lung diseases assumes the participation of systemic inflammation factors, as well as hormone-like substances produced by adipose tissue. The aim of this study was to evaluate the associations of certain adipokines/cytokines and chronic bronchitis against the background of abdominal obesity in young people. The study included 1415 people aged 25−44. In total, 115 people were selected by the random numbers method, who were divided into two subgroups: those with chronic bronchitis and abdominal obesity and those with chronic bronchitis without abdominal obesity. A control group of patients with comparable gender and age was also selected. In the group of patients with chronic bronchitis, adiponectin, TNFa and GIP levels were 1.4 times higher. The levels of C-peptide, MCP-1 and PP in the group of chronic bronchitis were 1.3 times higher compared to the control. Adipsin, lipocalin-2, IL-6 and resistin were significantly higher in the group with chronic bronchitis. Glucagon, amylin and ghrelin were 2.2, 2.3 and 3.2 times lower, respectively, in the group of patients with chronic bronchitis. Against the background of abdominal obesity, the probability of having chronic bronchitis increased with an increase in the level of lipocalin-2 and GIP and TNFa.

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“…Although pulmonary and renal diseases were considered as 12.4% associated with DM in elderly patients suggested that albuminuria and low glomerular filtration rate are associated with frontal lobe dysfunction in elderly type 2 diabetic patients [23]. Moreover in the elderly, male sex, diabetes, insulin therapy and high C-peptide immune reactivity levels were considered as risk factors [24]. Saudi patients were the most prevalence with 2061 patients (72.2%) compared with Arabic Middle East with 461 patients (16.2%) and other nationalities with (11.6%).…”

Section: Discussionmentioning

confidence: 99%

Untitled

2022

GGM

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The purpose of this study is to find suggestions on how to deliver adequate standard of care and reductions of hospitalizations in older people with diabetes, and to find out the prevalence of most associated diseases in elderly patients with diabetes.Methods: This retrospective cross-sectional study included patients aged ≥65 years with diabetes mellitus. Data were collected retrospectively from 2853 older patients diagnosed with diabetes mellitus, including sociodemographic characteristics and other comorbidities.Results: A total of 2853 elderly patients aged 74.1 years (±7.3 SD) were included, with an average of 2.68 (±0.9 SD) diseases associated with diabetes mellitus. In older patients, the disease most associated with diabetes mellitus was hypertension (2324 patients), followed by other heart diseases (927 patients). Most older patients had three comorbidities (1197 patients). Elderly with Diabetes Mellitus (DM) decreased with older age by 180 patients (15.85% of the patients) every 5 years. There were 1634 older male patients with DM compared with 1219 older female patients. Saudi patients were the most prevalent (2061 patients). Conclusion:There was a 15.85% decrease every 5 years in the number of older patients with DM, with this proportion decreasing in line with increasing age. Diabetes self-care monitoring is complex, and it is important to follow recommendations for dietary require-ments to achieve adequate standards for reducing hospitalization and appropriately managing diabetes.

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Characteristics of factors for decreased lung function in elderly patients with type 2 diabetes

Cited by 7 publications

References 30 publications

Risk for prolonged hospitalization and mortality in aged community acquired pneumonia patients: a retrospective study in Japan

Risk for prolonged hospitalization and mortality in aged community acquired pneumonia patients: a retrospective study in Japan

Blood Adipokines/Cytokines in Young People with Chronic Bronchitis and Abdominal Obesity

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