Characteristics of genital herpes in Bilbao (Northern Spain): 12-year retrospective study

Macho-Aizpurua, Mikele; Imaz-Pérez, Manuel; Álava-Menica, José Ángel; Hernández-Ragpa, Leonora; López-de-Munain-López, María-Josefina; Cámara-Pérez, Mari-Mar; Bilbao‐González, Amaia; Arco, José-Luis Díaz-de-Tuesta-del; Muñoz-Sánchez, Josefa; Basaras-Ibarzabal, Miren; Cisterna-Cáncer, Ramón

doi:10.1016/j.eimc.2020.04.014

Cited by 2 publications

(3 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In a retrospective study from 2004 to 2015 in Bilbao, Spain, the proportion of HSV-1 increased during the study period significantly in men (28 % in 2004-2007 vs 50 % in 2012-2015). Females were more commonly infected with HSV-1 than males (56 % vs 44 %) [12].…”

Section: Epidemiologymentioning

confidence: 98%

See 1 more Smart Citation

Asian guidelines for genital herpes

Sindhuja

Gupta

Bhari

et al. 2021

Journal of Infection and Chemotherapy

View full text Add to dashboard Cite

Prevention1. Regular male condom usage effectively reduces the transmission risk of genital HSV-2 infection (LE: 2A, GR: B); there is no added advantage of the vaginal diaphragm (LE: 1B, GR: A).2. The evidence is mixed regarding circumcision as a preventive measure against genital herpes in males and their spouses.3. Oral valacyclovir (but not acyclovir) and vaginal tenofovir 1 % gel have been shown to reduce the risk of sexual transmission in susceptible partners and women, respectively (LE: 1B, GR: A).4. Limited data on the use of anti-HSV vaccines suggests that it is not significantly effective in preventing genital herpes (LE: 1B, GR: B).Diagnosis 1. Tzanck smear is a rapid point-of-care test that yields quick results but is highly operator skill-dependant. (LE: 3) 2. Virus antigen can be detected using either DIF or antigen capture EIA. (LE: 3). It is recommended to perform HSV typing in patients with first-episode genital herpes. (LE: 3) 3. Viral culture has been traditionally considered the 'Gold standard' in diagnosing genital herpes. (LE: 4) 4. PCR is more sensitive than viral culture. (LE: 1B) It is widely regarded as the test of choice for the diagnosis of genital herpes in symptomatic patients. (LE: 4) 5. Serology: Seroconversion or a rising titre of antibodies has diagnostic significance. (LE: 2A) Type-specific assays which detect IgG antibodies against antigenically unique glycoproteins G1 and G2 should be used. (LE: 3). TreatmentFirst episode genital herpes 1 Oral acyclovir, valacyclovir and famciclovir are similarly effective in reducing the severity and duration of symptoms (LE: 1A, GR: A). Topical antivirals are not effective in reducing symptoms (LE: 1A, GR: A), and topical acyclovir is associated with resistance to oral acyclovir (LE: 3, GR:B).

show abstract

Section: Epidemiologymentioning

confidence: 98%

“…Clinical recurrences are also more common and earlier in HSV-2 infections than HSV-1 infections [12]. Ninety percent of patients with HSV-2 infection have at least one recurrence during the first year, compared to 60 % in patients with HSV-1 infection.…”

Section: Natural Historymentioning

confidence: 99%

Asian guidelines for genital herpes

Sindhuja

Gupta

Bhari

et al. 2021

Journal of Infection and Chemotherapy

View full text Add to dashboard Cite

show abstract

“…Algunas series de casos en la literatura determinan una media de edad en torno a los 26-30 años y en torno a un 40% de los casos presentan coinfecciones con otros patógenos relacionados con prácticas sexuales no seguras [29,30]. Las infecciones por VHS-1 fueron más frecuentes que por VHS-2, lo cual confirma la tendencia que recoge la OMS y estudios recientes de un aumento de infecciones genitales por VHS-1, tradicionalmente causante de la infección oral [31]. Como posibles explicaciones para este cambio de tendencia, se incluyen los cambios en las prácticas sexuales, sin poder descartar cambios en la patogenicidad viral, así como un retraso en el contacto con el VHS-1 en la infancia que hace a los adultos más susceptibles a desarrollar la infección [32].…”

Section: Tablaunclassified

Increased infections by herpes simplex virus type 1 and polymicrobials of the genital tract, in the general population of a Spanish middle city

Pérez-Torralba¹,

Ruiz-Olivares²,

Sanbonmatsu‐Gámez³

et al. 2021

Rev Esp Quimioter

View full text Add to dashboard Cite

Introduction. Infections by genitopathogens are a frequent reason for consultation in Primary Health Care and in the specialties of Infectious Diseases, Urology, Gynecology, and Dermatology. The most common causes are opportunistic microorganisms and responsible for sexually transmitted infections associated with unprotected sex. The objective is to determine the microorganisms that cause these infections in patients treated at the Hospital Universitario Virgen de las Nieves in Granada and Neisseria gonorrhoeae susceptibility to antibiotics. Material and methods. A transversal-descriptive and retrospective study was carried out, which included the results issued, between January 2018 and December 2019, in the Microbiology Laboratory from all the episodes studied using standardized working procedures. Results. The most frequently detected microorganisms were Gardnerella vaginalis (23.81%) followed by Candida spp. (20.9%), especially in females, and N. gonorrhoeae (11.36%) and Ureaplasma urealyticum (11.99%), in males. Many times, they were presented in combination. Regarding herpes simplex viruses, infection by both species had a similar prevalence (50%) in males, while type 1 was more prevalent (76.52%) in females. The most active antibiotics against N. gonorrhoeae were cefotaxime (98%) and cefixime (100%). Tetracycline (39.02%) a poorly active antibiotic. Conclusions. The most frequent pathogens corresponded to those that usually caused infections in females, although N. gonorrhoeae was the most frequent in males and mixed infections are not an accidental finding. HSV-1 infections were more frequent than HSV-2, confirming the trend of a change in the epidemiology of genital herpes.

show abstract

Characteristics of genital herpes in Bilbao (Northern Spain): 12-year retrospective study

Cited by 2 publications

References 26 publications

Asian guidelines for genital herpes

Asian guidelines for genital herpes

Increased infections by herpes simplex virus type 1 and polymicrobials of the genital tract, in the general population of a Spanish middle city

Contact Info

Product

Resources

About