Characteristics of hemolysins from pathogenic bacteria in tropical aquaculture: an in-silico study

Abstract

Some species of known pathogenic bacteria isolates in tropical aquaculture produces hemolysin. Hemolysin can be identified based on its ability to break down red blood cells in vitro. Some hemolysin is a pore-shaped poison that can damage cell membranes and kill host cells. The character of the 13 sequences of hemolysin protein in several pathogenic bacterial isolates in tropical aquaculture was analysed using the NCBI protein bioinformatics database. The phylogenetic tree was generated, and the analysis was conducted using the base character method (Maximum Parsimony) of Mega 6.06 software. The result showed that there are two big family of hemolysin from the known pathogenic bacteria. The closest characteristics of protein sequences were hemolysin of Streptococcus agalacticae and of S. iniae.

Characterization of a hemolytic and antibiotic-resistant Pseudomonas aeruginosa strain S3 pathogenic to fish isolated from Mahananda River in India

“…aeruginosa S3 resistant to multiple antibiotics was isolated from the Mahananda river. Hemolytic activity, a key indicator of virulence in several bacteria in the aquatic environment [ 46 ] was utilized during the initial screening. Among 26 hemolytic isolates, S3 possessed the highest hemolytic activity and exhibited multiple virulence traits which led to its selection for further studies to genotypically and phenotypically characterize this strain to understand the threat it poses to aquatic organisms and human health.…”

“…In this present research, a pathogenic strain of P. aeruginosa S3 resistant to multiple antibiotics was isolated from the Mahananda river. Hemolytic activity, a key indicator of virulence in several bacteria in the aquatic environment [46]…”