Characteristics of Hyperautofluorescent Choroidal Vessels Using Fundus Camera Type Short-Wavelength Autofluorescence

Abstract

Purpose: To clarify differences between eyes showing hyperautofluorescent choroidal vessels in both nasal and temporal, or only the nasal, portions of the fundus using fundus autofluorescence. Methods: Nineteen eyes with hyperautofluorescent vessels in both nasal and temporal portions (group 1) and 17 only the nasal portion (group 2) of the fundus were studied. Choroidal and retinal thicknesses (foveal, and nasal and temporal 3,000 µm from the fovea), axial length, and refraction were compared between the two groups. Results: In group 1, the average foveal, nasal, and temporal choroidal thicknesses (mean ± SD) were 69.0 ± 30.9, 57.1 ± 18.7, and 88.3 ± 30.4 μm, retinal thicknesses 170.1 ± 48.5, 221.9 ± 46.5, and 209.5 ± 37.9 μm, axial length 28.2 ± 2.2 mm, and refraction -9.9 ± 5.9 dpt. In group 2, the respective values were 174.8 ± 43.0, 80.5 ± 20.9, and 173.5 ± 46.1 μm, 213.4 ± 29.8, 278.3 ± 20.2, and 252.8 ± 19.6 μm, 24.2 ± 1.4 mm, and -1.8 ± 3.8 dpt. There were significant between-group differences for all items (p < 0.05). Conclusions: Fundus autofluorescence tends to be associated with the detection of hyperautofluorescent choroidal vessels in eyes with strong myopia or greater axial length.

Relation between dry eye and myopia based on tear film breakup time, higher order aberration, choroidal thickness, and axial length

“…Parapapillary diffuse choroidal atrophy, which involves extreme thinning of parapapillary choroid 42 , is a potential precursor of pathologic myopia 43 . The CT is correlated negatively with the AL in patients with high myopia 29 , 30 and healthy subjects 31 Our results also showed that the CT is correlated negatively with the AL. We can suggest two plausible explanations for the association between the TBUT and CT. First, since increased parasympathetic tone enhances both the CT 27 and the amount of tear secretion from the lacrimal glands 28 , our results suggested that a “factor X”, including the parasympathetic nervous system, might be a common factor upstream in the association between the TBUT (DED) and CT (myopia) (Fig.…”

Multicolor imaging in central serous chorioretinopathy – a quantitative and qualitative comparison with fundus autofluorescence

“…Choroidal vessels have been visualized as hyperautofluorescent linear lines on short-wavelength FAF in studies in the past. This FAF finding has been typically described in conditions (choroidal sclerosis and high myopia) wherein the RPE and choriocapillaris have undergone thinning and hence led to enhanced visualization of underlying larger choroidal vessels 28,29 . We observed similar findings in one of our subjects wherein diffuse RPE and choriocapillaris atrophy secondary to CSCR lead to clearly visible hyperautofluorescent pachyvessels on FAF (bottom right Fig.…”

Multiple Factors Causing Myopia and the Possible Treatments: A Mini Review

“…Others, as well as our team, have reported that myopia is associated with subfoveal choroidal thickness which is significantly related to refractive error ( 13 – 15 ) and axial length ( 13 , 16 ). Choroidal thickness is also reported to fluctuate in response to diurnal variation and changes in visual input ( 17 – 19 ).…”