Characteristics of Oral Mucosal Lesions and Their Association With Socioeconomic Status and Systemic Health: A Cross-Sectional Study of Consecutively Collected Oral Medicine Clinic Data in a Remote Rural Area of China

Yao, Hui; Zhang, Qiongyue; Song, Qisheng; Liu, Mingshan; Tang, Guoyao

doi:10.3389/fpubh.2022.897814

Cited by 9 publications

(5 citation statements)

References 31 publications

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“…Встановили, що РАС частіше діагностують у пацієнтів із ВІЛ-інфекцією. Імовірно, це пов'язано зі зміною співвідношення CD4/CD8 і зниженням кількості нейтрофілів [8,10].…”

Section: мета роботиunclassified

Etiopathogenetic features of recurrent aphthous stomatitis: modern approaches to prevention and treatment

Hanchev¹,

Кокарь²

2023

ZMJ

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Recurrent aphthous stomatitis (RAS) is an inflammatory disease of the oral mucosa, which has a chronic course with periods of remission and exacerbations. RAS requires adequate diagnosis for the purposes of properly treating. The study on RAS remains relevant over many years and continues to be a priority in modern dentistry. The aim of the work is to analyze the information in the professional literature on pathogenetic variants of RAS and approaches to its treatment and prevention. Despite the variety of studies, the etiology and pathogenesis of the disease remain the subject of numerous discussions. This article provides a review of current research on the main etiopathogenetic mechanisms of the disease development and progression, specifies current recommendations for therapeutic approaches to treatment and prevention. Conclusions. To date, there is no definitive therapeutic tactic for recurrent aphthous stomatitis, so it is advisable to systematize and study methods for the prevention and treatment of this pathology, including pain relief, acceleration of ulcer healing and reduction of its episode frequency and severity. Considering the etiopathogenetic variant of the disease development (metabolic disorders, stress, allergies, etc.), preventive measures should be comprehensive and include oral hygiene, a sparing diet, multivitamin and micro-, macroelement complexes, etc.

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Section: мета роботиunclassified

Etiopathogenetic features of recurrent aphthous stomatitis: modern approaches to prevention and treatment

Hanchev¹,

Кокарь²

2023

ZMJ

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“…Однак як часто буває із захворюваннями, що знаходяться на межі декількох спеціальностей, патології СОПР приділяли порівняно мало уваги як стоматологи, так і лікарі інших спеціальностей [7]. Складність вивчення та діагностики уражень СОПР полягають у різноманітті захворювань, що локалізуються в цій ділянці, відмінності їх етіології, патогенезу та часто в значній схожості клінічних проявів [39,40]. Водночас слід зауважити, що етіологія і патогенез багатьох захворювань СОПР, що проявляються в цій ділянці, остаточно не встановлені.…”

Section: вступunclassified

Manifestations of systemic connective tissue diseases on the oral mucosa: a literature review

Povsheniuk,

Shinkaruk-Dykovytska,

Gadzhula

et al. 2023

Rep. of Vinnytsia Nation. Med. Univ.

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Annotation. Despite the modern high level of medical care, autoimmune connective tissue diseases cause a lot of questions among scientists and are a significant problem for society. At the same time, in the scientific works available today, little attention is paid to the manifestations of connective tissue diseases in the oral cavity and modern diagnostics of the main types of dental pathology in such patients, which would have great scientific and practical importance. Therefore, the purpose of the review article was to perform an analysis of the scientific literature regarding orofacial manifestations of autoimmune connective tissue diseases. When using the following databases: PubMed, Google Scholar, Scopus, Web of Science and various combinations of keywords and subject headings of MESH such as “oral manifestations”, “oral mucosal lesions”, “autoimmune diseases”, “rheumatic diseases”, “connective tissue diseases”, “systemic lupus erythematosus”, “rheumatoid arthritis”, “systemic sclerosis”, “Sjögren’s syndrome”, “dermatomyositis”, 40 articles were chosen, which corresponded to the purpose of the study. The search results indicate that there is a direct correlation between the duration of the main disease and the severity of oral symptoms. Pronounced hyposalivation and dryness of oral mucosa are the most similar common signs of autoimmune diseases, which contributes to functional disorders and diseases of oral cavity. Oral manifestations are quite often a side effect of the treatment of connective tissue diseases. The pathology of oral mucosa in autoimmune diseases remains not well-understood, so makes it difficult to clarify its pathogenesis in detail, that would allow for the development of justified measures of prevention and treatment.

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“…Patients with RA are often diagnosed with rampant caries, cervical necrosis of hard dental tissues, generalized periodontitis, and Sjogren's syndrome [5,6,7]. The close relationship of oral mucosa with the condition of internal organs and systems causes the occurrence of functional and structural changes in it in various systemic diseases [8]. However, not enough attention is paid to the issue of lesions of the oral mucosa associated with RA.…”

Section: Introduction / вступmentioning

confidence: 99%

Assessing Mucosal Immunity in Patients With Oral Diseases Associated With Rheumatoid Arthritis

Povsheniuk,

Gadzhula,

Rekun

2024

EUMJ

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Introduction. The association between diseases of connective tissue and oral cavity are of increased interest for scientists because they can contribute to the burden of the pathological process of each other and the occurrence of recurrences. Given that autoimmune disorders in rheumatoid arthritis are the main ones, it is advisable to study the specific and non-specific immunity features of the oral cavity in associated diseases. Methods. The research group included 19 patients with benign migratory glossitis and 16 patients with atrophic glossitis. 15 practically healthy persons made up the control group. The levels of IgA, IgG and lysozyme were determined by radial immunodiffusion according to Mancini method and with the use of biomass powder of Micrococcus lysodeicticus, respectively. Statistical analysis of the obtained results was performed using Statistica 6.1. Results. The high levels of IgG in the oral fluid was found in both research groups (p<0.001). In patients with benign migratory glossitis, high levels of secretory IgA (p>0.05) and serum IgA (p<0.001) were found, while in patients with atrophic glossitis associated with rheumatoid arthritis, there was a significant decrease in the content of sIgA and lysozyme, and similar increase in mIgA content. Conclusions. Oral mucosal diseases associated with RA are accompanied by suppression of defense mechanisms of the oral cavity and its local immunity, which is characterized by a decrease in the levels of lysozyme and secretory IgA in the oral fluid of patients.

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Characteristics of Oral Mucosal Lesions and Their Association With Socioeconomic Status and Systemic Health: A Cross-Sectional Study of Consecutively Collected Oral Medicine Clinic Data in a Remote Rural Area of China

Cited by 9 publications

References 31 publications

Etiopathogenetic features of recurrent aphthous stomatitis: modern approaches to prevention and treatment

Etiopathogenetic features of recurrent aphthous stomatitis: modern approaches to prevention and treatment

Manifestations of systemic connective tissue diseases on the oral mucosa: a literature review

Assessing Mucosal Immunity in Patients With Oral Diseases Associated With Rheumatoid Arthritis

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