Characteristics of ovarian endometrioma during pregnancy

Endometriosis is a gynecological estrogen-dependent disease whose commonest pain symptoms are dysmenorrhea, dyspareunia, and acyclic chronic pelvic pain (CPP). Hormonal changes occurring during breastfeeding seem to reduce pain and disease recurrence. The aim of this observational prospective study was to assess the effect of breastfeeding on pain and endometriotic lesions in patients with endometriosis and to evaluate a possible correlation between the duration of breastfeeding, postpartum amenorrhea, and pain. Out of 156 pregnant women with endometriosis enrolled, 123 who breastfed were included in the study and were monitored for 2 years after delivery; 96/123 exclusively breastfed for at least 1 month. Mode of delivery, type and duration of breastfeeding, intensity of pain symptoms, and lesion size before pregnancy and during the 24-month follow-up were analyzed. All patients experienced a significant reduction in dysmenorrhea proportional to the duration of breastfeeding. CPP was significantly reduced only in women who exclusively breastfed. No significant improvement in dyspareunia was observed. Ovarian endometriomas were significantly reduced. Therefore, breastfeeding, particularly if exclusive, may cause improvement in dysmenorrhea and CPP proportional to the duration of breastfeeding, as well as a reduction in the size of ovarian endometriomas.

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“…In fact, recently, Takami at al. reported a reduced volume of ovarian endometriomas in 68% of cases during pregnancy [56].…”

Section: Discussionmentioning

confidence: 96%

Effects of Breastfeeding on Endometriosis-Related Pain: A Prospective Observational Study

Porta¹,

Sangiuliano

Cavalli

et al. 2021

IJERPH

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“…According to the literature, the prevalence is less than 3% among women with endometriosis [ 23 ]. This complication can develop spontaneously, there are cases reported during menstruation [ 24 ] and periovulatory stages [ 25 ], but it more often occurs during pregnancy, after abdominal and pelvic trauma [ 26 ]. Also, the risk is higher when the diameter of endometrioma is ≥6cm [ 27 ].…”

Section: Discussionmentioning

confidence: 99%

“…Also, the risk is higher when the diameter of endometrioma is ≥6cm [ 27 ]. Takami et al [ 26 ] reported a 2.8% incidence of the rupture of ovarian endometrioma during pregnancy. They also found enlarging cyst size, adhesion to the adjacent organs and the pressure of rapidly growing uterus being the main risk factors associated with rupture.…”

Section: Discussionmentioning

confidence: 99%

Acute Diffuse Peritonitis Due to Spontaneous Rupture of an Infected Endometrioma: A Case Report

Petruškevičiūtė

Bužinskienė

2021

AML

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Background. Endometriosis is defined as a chronic, inflammatory, estrogen-dependent gynaecologic disease. It affects approximately 5–10% of reproductive-age women worldwide. Ovarian endometriosis is the most frequent form of this condition. Endometriotic cysts are found in about 17–44% of women diagnosed with endometriosis. It is well known, that ovarian endometriomas can cause infertility and chronic pelvic pain. Enlarging cysts can also cause ovarian torsion. In addition, ovarian endometriosis slightly increases the risk for ovarian cancer. The rupture of endometriotic ovarian cysts is an exceptional complication. According to the literature, the prevalence is less than 3% among women with endometriosis. The rupture of an ovarian endometrioma can cause acute peritonitis, which can lead to sepsis, septic shock and can be lethal. The occurrence of abscesses within an ovarian endometrioma is an extremely rare complication. Generally, the origin of infected endometriotic ovarian cysts is related to the previous invasive procedures involving pelvic organs or the use of intrauterine devices. Also, ovarian abscesses can be caused by the hematogenous or lymphatic spread of bacteria. Although, the literature points out that infection of endometriotic ovarian cysts can develop spontaneously. In these rare cases, reservoir and route of infection remains an enigma.Case report. A 49-year-old female was brought to the emergency room with severe generalized lower abdominal pain (6/10) and three days lasting fever. Abdominal examination revealed diffuse abdominal pain with anterior abdominal wall muscle tension. Painful solid masses were felt on both sides of the uterus during the pelvic examination. Cystic masses were detected in both ovaries during transvaginal sonography. Computer tomography (CT) of the abdomen and pelvis revealed abnormal changes in both ovaries. A small amount of free fluid was found in the pelvic cavity along with thickened pelvic peritoneum. Suspecting acute peritonitis and bilateral tubo-ovarian abscesses, surgical treatment was performed. Lower midline laparotomy with bilateral adnexectomy and abdominal lavage with 4000 ml normal saline were done. The outcome of peritonitis was evaluated using the Mannheim peritonitis index (MPI=17 – low risk of morbidity and mortality). The histopathological examination revealed the diagnosis of bilateral endometriotic cysts complicated with acute inflammation, with associated acute inflammation of both fallopian tubes. Microbiological cultures from the purulent fluid were negative.Conclusions. Although the occurrence of abscesses within an ovarian endometrioma is an extremely rare finding in clinical practice, it has to be considered by gynaecologists because it might result in a surgical emergency that can be life-threatening. Being aware of the risk factors of abscesses within an endometrioma can lead to an early diagnosis of this rare condition and help to avoid serious complications.

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“…This complication most commonly occurs during pregnancy, because of the rapid growth of endometrioma due to hormonal stimulation [ 28 , 29 ]. Clinically, endometrioma rupture may mimic the rupture of a hemorrhagic ovarian cyst with findings ranging from symptoms of inflammation, such as fever, leukocytosis, and elevated c-reactive protein, to acute abdominal pain and signs of hypovolemic shock [ 30 , 31 ].…”

Section: Gynecologic Complicationsmentioning

confidence: 99%

Acute abdominal pain in women of reproductive age: keys to suggest a complication of endometriosis

et al. 2023

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Although endometriosis is a common gynecological condition in women of reproductive age, a complication of endometriosis is rarely considered as the differential diagnosis of acute abdominal pain in that context. However, acute events in women with endometriosis can represent life-threatening conditions, which require emergent treatment and often surgical management. Mass effect of endometriotic implants can give rise to obstructive complications, specifically occurring in the bowel or in the urinary tract, while inflammatory mediators released by ectopic endometrial tissue can lead to inflammation of the surrounding tissues or to superinfection of the endometriotic implants. Magnetic resonance imaging is the best imaging modality to reach the diagnosis of endometriosis, but an accurate diagnosis is possible on computed tomography, especially in the presence of stellar, mildly enhanced, infiltrative lesions in suggestive areas. The aim of this pictorial review is to provide an image-based overview of key findings for the diagnosis of acute abdominal complications of endometriosis. Graphical Abstract

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Characteristics of ovarian endometrioma during pregnancy

Cited by 5 publications

References 27 publications

Effects of Breastfeeding on Endometriosis-Related Pain: A Prospective Observational Study

Effects of Breastfeeding on Endometriosis-Related Pain: A Prospective Observational Study

Acute Diffuse Peritonitis Due to Spontaneous Rupture of an Infected Endometrioma: A Case Report

Acute abdominal pain in women of reproductive age: keys to suggest a complication of endometriosis

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