Characteristics of Patients Diagnosed with Osteoporosis in South Korea: Results from the National Claim Registry

Yoon, Hyun Sik; Lee, Yong Seuk; Ha, Yong‐Chan

doi:10.11005/jbm.2017.24.1.59

Cited by 9 publications

(13 citation statements)

References 21 publications

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“…Because the HIRA data did not include bone mineral density (BMD) measurements using dual energy X-ray absorptiometry (DXA), an accurate osteoporosis diagnosis could not be obtained using T-scores. [ 10 , 11 ] In Korea, there is a risk of overestimation when the diagnosis is considered, because the diagnostic code of osteoporosis can be used even in the diagnostic work-up process to apply for medical insurance. To avoid overestimation, we operationally defined osteoporosis as a diagnostic code for osteoporosis (M80–M82 according to the ICD-10 classification) plus a prescription for bisphosphonate or raloxifene or the occurrence of osteoporotic fractures after index gastrectomy.…”

Section: Methodsmentioning

confidence: 99%

Osteoporosis and fracture after gastrectomy for stomach cancer

2018

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This study was planned to evaluate the incidence and risk factors of osteoporosis and fracture after gastrectomy for stomach cancer using a nationwide claims database in South Korea.Data from 41,512 patients (50–79 years) who underwent gastrectomy for stomach cancer from 2008 to 2010 with at least 5 years of follow-up were obtained from the Health Insurance Review and Assessment Service database. Patients diagnosed with osteoporosis and prescribed bisphosphonate or raloxifene or who experienced osteoporotic fractures after gastrectomy were operationally defined as osteoporosis. Osteoporotic fracture was defined as a fracture at common osteoporotic fracture sites (spine, pelvis, hip, forearm, or rib).In total, 37,076 patients were included in the final analysis. The incidences of postgastrectomy osteoporosis and osteoporotic fractures were 41.9 and 27.6 cases per 1000 person-years, respectively. Multivariate analysis showed that older age (hazard ratio [HR] 1.88; 95% confidence interval [CI] 1.79–1.96), female gender (HR 2.46; 2.35–2.58), total gastrectomy (HR 1.10; 1.04–1.16), and diabetes (HR 1.16; 1.11–1.22) were significantly associated with osteoporosis and that older age (HR 1.90; 95% CI 1.80–2.01), female gender (HR 1.50; 1.41–1.58), total gastrectomy (HR 1.17; 1.10–1.25), chemotherapy (HR 1.06; 1.00–1.12), and diabetes (HR 1.26; 1.19–1.33) were significantly associated with fractures. Osteoporotic fractures occurred a median 3.1 years after gastrectomy. Among the 5175 fracture patients, 780 (15.1%) experienced multisite fractures, mostly in the elderly and chemotherapy groups.The osteoporosis and osteoporotic fracture incidences are high in patients within a relatively short timeframe after gastrectomy for stomach cancer. Systematic management of osteoporosis is necessary after this surgery.

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Section: Methodsmentioning

confidence: 99%

Osteoporosis and fracture after gastrectomy for stomach cancer

2018

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“…Several epidemiologic studies have used this national claim database. [ 19 20 21 ] We analyzed patients aged over 50 years who were diagnosed with osteoporotic fracture by physician at 2010.…”

Section: Methodsmentioning

confidence: 99%

Factors Affecting Bone Mineral Density Measurement after Fracture in South Korea

Kim

Lee

2017

J Bone Metab

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BackgroundPrior osteoporotic fractures are strongly associated with the subsequent fractures. To prevent this, the diagnosis of osteoporosis following an osteoporotic fracture is important. The measurement of bone mineral density (BMD) is the first step for the diagnosis and management of osteoporosis. Therefore, the purposes of this study are 1) to evaluate the rate of BMD measurement after osteoporotic fracture in Korean population; and 2) determine the associated factors with BMD measurement after fractures among Korean patients.MethodsFrom database of Health Insurance Review & Assessment Service, we identified patients with osteoporotic fractures happened in 2010. The BMD examinations were evaluated by using procedure codes. We evaluated the rate of BMD measurement within 6 months after fracture according to gender, age group (10-year incremental), type of insurance, residency area (rural vs. urban), type of medical institute, department, history of depression, rheumatoid arthritis, medical history suggestive of secondary osteoporosis, osteoporosis-induced drug, and number of family members.ResultsDuring study period, about a half (53.9%) of patients with osteoporotic fractures had BMD measurement. Men, younger age, urban residency, and depression history were associated with low rate of BMD measurement. However, increasing age, use of glucocorticoid use, osteoporosis-inducing comorbid disease including rheumatologic disease, and osteoporosis-induced drug user were associated with higher likelihood of BMD measurement.ConclusionsOur results showed that about a half of patients with osteoporotic fractures had BMD measurement in South Korea, and provided the basic information to encourage management after fracture by educating not only patient but also physician about post-fracture management.

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“…All clinics and hospitals should submit the diagnoses data defined by the International Classification of Diseases, 10th Revision (ICD-10), of inpatients and outpatients with demographic information for claims. 16 To identify osteoporosis patients, we adopted the previously developed algorithm by Ha and colleagues 4,16,17 : (1) among Koreans 45 years of age and older, eligible participants were selected by ICD-10 codes of M80 (osteoporosis with pathologic fractures), M81 (osteoporosis without pathologic fractures), and M82 (osteoporosis in other diseases); (2) participants were included who had prescriptions of medications exclusively for osteoporosis treatment (bisphosphonate, selective estrogen receptor modifier, and calcitonin); (3) elderly patients (males: ≥70 years, females: ≥65 years) with an ICD diagnostic code; (4) a history of prescribed medications that caused osteoporosis with an ICD diagnostic code; (5) a history of a disease that causes osteoporosis with an ICD diagnostic code of osteoporosis; and (6) last, an osteoporosis-related fracture such as vertebral fractures with M48.4 (fatigue fracture of vertebra), M48.5 (collapsed vertebra, NEC), S22.0 (fracture of thoracic vertebra), S22.1 (multiple fractures of thoracic spine), S32.0 (fracture of lumbar vertebra); wrist fractures with S52.5 (fracture of lower end of radius) and S52.6 (fracture of lower end of both ulna and radius); hip fractures with S72.0 (fracture of neck of femur) and S72.1 (pertrochanteric fracture). Each fracture code should be accompanied by a doctor’s claim to reduce or repair the site-specific fracture (either open or closed) to improve the specificity of the coding.…”

Section: Methodsmentioning

confidence: 99%

Burden of Osteoporotic Fractures Using Disability-Adjusted Life Years in South Korea

Bae

Kim

Kwon

et al. 2020

Asia Pac J Public Health

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There is an increase in the number of patients with osteoporotic fractures due to the aging population in Korea. This study investigated the burden of osteoporotic fractures including hip, spine, and wrist fractures in the Korean population by estimating disability-adjusted life years (DALYs). The DALY for a given condition in a population captures years of life lost due to premature death and years of life lived with a disability and its severity and duration. To calculate DALYs from all relevant data collected for the 3 conditions, we used a DALY calculation template provided by the World Health Organization in 2014. DALYs per 100 000 for vertebral fractures (3168) were higher than those of hip fractures (2496) in women. Wrist fractures (1038) had the least burden, and the difference between men and women was the lowest. The aging population is expected to increase the burden of osteoporosis.

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Characteristics of Patients Diagnosed with Osteoporosis in South Korea: Results from the National Claim Registry

Cited by 9 publications

References 21 publications

Osteoporosis and fracture after gastrectomy for stomach cancer

Osteoporosis and fracture after gastrectomy for stomach cancer

Factors Affecting Bone Mineral Density Measurement after Fracture in South Korea

Burden of Osteoporotic Fractures Using Disability-Adjusted Life Years in South Korea

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