Characteristics of Patients Presenting with LUTS/BPH in Six European Countries

Hutchison, Annie; Farmer, Richard; Chapple, Christopher R.; Berges, Richard; Pientka, Ludger; Teillac, P.; Borkowski, Andrzej; Dobroński, P.

doi:10.1016/j.eururo.2006.05.001

Cited by 64 publications

(39 citation statements)

References 19 publications

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“…Moreover, our study demonstrates a continuous and significant decrease of voiding efficiency in men with increasing BOO grade and, for the first time as well, a significant correlation between BCI and W max . Our results in a large group of unselected men, who were evaluated for LUTS suggestive of BPH during a 10-year period in one hospital with almost identical characteristics compared to those analyzed for health seeking behavior in Europe [21], show a strong correlation between BCI and W max and also a strong correlation between BOO and the two detrusor contraction power parameters. According to the literature, a BCI value < 100 indicates DU ('hypocontractility') in men [18], but this threshold value has never been validated and could refer to patients with BOO only.…”

Section: Discussionmentioning

confidence: 68%

Detrusor contraction power parameters (BCI and W max) rise with increasing bladder outlet obstruction grade in men with lower urinary tract symptoms: results from a urodynamic database analysis

2014

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In adult male LUTS patients, detrusor contraction power parameters-BCI and W max-continuously increase with rising BOO grade. According to our results, it is impossible to determine a single threshold value for detrusor contraction power to diagnose detrusor underactivity in a group of LUTS patients with different BOO grades. The study is limited to men with non-neurogenic LUTS. Future studies should evaluate exact threshold values for BCI and W max in BOO subgroups to adequately define detrusor underactivity and investigate men with other bladder conditions.

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Section: Discussionmentioning

confidence: 68%

Detrusor contraction power parameters (BCI and W max) rise with increasing bladder outlet obstruction grade in men with lower urinary tract symptoms: results from a urodynamic database analysis

2014

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“…Bother of symptoms increases in severity with increasing age 1,2. The health care costs for BPH are included in the 10 most prominent and costly diseases in men >50 years of age in the United States 3.…”

Section: Introductionmentioning

confidence: 99%

Two-year results after convective radiofrequency water vapor thermal therapy of symptomatic benign prostatic hyperplasia

Dixon

Cedano²,

Pacík

et al. 2016

RRU

105

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ObjectiveThe objective of this study was to assess the effectiveness and safety of convective radiofrequency (RF) water vapor thermal therapy in men with lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH); a pilot study design with 2-year follow-up evaluations.Patients and methodsMen aged ≥45 years with an International Prostate Symptom Score ≥13, a maximum urinary flow rate (Qmax) ≤15 mL/s, and prostate volume 20–120 cc were enrolled in a prospective, open-label pilot study using convective RF water vapor energy with the Rezūm System. Patients were followed up for 2 years after transurethral thermal treatment at 3 international centers in the Dominican Republic, Czech Republic, and Sweden. The transurethral thermal therapy utilizes radiofrequency to generate wet thermal energy in the form of water vapor injected through a rigid endoscope into the lateral lobes and median lobe as needed. Urinary symptom relief, urinary flow, quality of life (QOL) impact, sexual function, and adverse events (AEs) were assessed at 1 week, 1, 3, 6, 12, and 24 months.ResultsLUTS, flow rate, and QOL showed significant improvements from baseline; prostate volumes were appreciably reduced. Sexual function was maintained and no de novo erectile dysfunction occurred. The responses evident as early as 1 month after treatment remained consistent and durable over the 24 months of study. Early AEs were typically transient and mild to moderate; most were related to endoscopic instrumentation. No procedure related to late AEs were seen.ConclusionThe Rezūm System convective RF thermal therapy is a minimally invasive treatment for BPH/LUTS which can be performed in the office or as an outpatient procedure with minimal associated perioperative AEs. It has no discernable effect on sexual function and provides significant improvement of LUTS that remain durable at 2 years.

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“…However, contemporary studies of the neurobiologic basis for stress and anxiety offer a plausible mechanism whereby physical or psychological abuse can sensitize micturition pathways, leading to an overactive bladder characterized by urinary urgency, usually with frequency or nocturia [17[en]19]. Urologic symptoms are not uncommon in the population [20,21].…”

Section: Introductionmentioning

confidence: 99%

Is Abuse Causally Related to Urologic Symptoms? Results from the Boston Area Community Health (BACH) Survey

et al. 2007

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Objectives: We investigated (1) whether sexual, physical, or emotional abuse experienced either as a child or as an adolescent/adult is associated with symptoms of urinary frequency, urgency, and nocturia, and (2) the extent to which the observed association between abuse and urologic symptoms may be causal. Methods:Analyses are based on data from the Boston Area Community Health (BACH) survey, a community-based epidemiologic study of many different urologic symptoms and risk factors. BACH used a multistage stratified cluster sample to recruit 5506 adults, aged 30[en]79 yr (2301 men, 3205 women; 1770 black [African American], 1877 Hispanic, and 1859 white respondents). Results:The symptoms considered are common, with 33% of BACH respondents reporting urinary frequency, 12% reporting urgency, and 28% reporting nocturia. All three symptoms are positively associated with childhood and adolescent/adult sexual, physical, and emotional abuse (p < 0.05), with abuse significantly increasing the odds of urinary frequency by a factor ranging from 1.6 to 1.9, the odds of urgency by a factor from 2.0 to 2.3, and the odds of nocturia by a factor from 1.3 to 1.5. Conclusions:Our analyses extend previous work. First, we show a strong association between abuse and urinary frequency, urgency, and nocturia in a community-based random sample. Second, we move beyond discussion of statistical association and find considerable evidence to suggest that the relationship between abuse and these symptoms may be causal.

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Characteristics of Patients Presenting with LUTS/BPH in Six European Countries

Cited by 64 publications

References 19 publications

Detrusor contraction power parameters (BCI and W max) rise with increasing bladder outlet obstruction grade in men with lower urinary tract symptoms: results from a urodynamic database analysis

Detrusor contraction power parameters (BCI and W max) rise with increasing bladder outlet obstruction grade in men with lower urinary tract symptoms: results from a urodynamic database analysis

Two-year results after convective radiofrequency water vapor thermal therapy of symptomatic benign prostatic hyperplasia

Is Abuse Causally Related to Urologic Symptoms? Results from the Boston Area Community Health (BACH) Survey

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