Characteristics of Peripapillary Choroidal Cavitation Detected by Optical Coherence Tomography

Yeh, Shu‐I; Chang, Wei-Chun; Wu, Chien-Hsiu; Lan, Yu-Wen; Hsieh, Jui-Wen; Tsai, Shih‐Wei; Chen, Lee-Jen

doi:10.1016/j.ophtha.2012.08.028

Cited by 36 publications

(60 citation statements)

References 13 publications

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“…The reason for the discrepancy may be differences in the study populations, in the study design (population-based versus hospital-based), in the ethnicity (Chinese versus Japanese) or others. In the study by Yeh and colleagues, PICCs were described to be also present in emmetropic and hyperopic eyes [10], while in our investigation, PICCs were detected only in highly myopic eyes. The reason for the discrepancy between both studies may have been differences in the definition of PICCs.…”

Section: Discussioncontrasting

confidence: 58%

“…It was initially named “peripapillary detachment in pathologic myopia”. After the introduction of optical coherence tomography (OCT) into clinical practice, one observed that PICC was characterized by an intrachoroidal hyporeflective space with normal overlying retina and retinal pigment epithelium (RPE) [2-10]. It was additionally detected that eyes with PICC tended to show glaucoma-like visual field defects [11].…”

Section: Introductionmentioning

confidence: 99%

“…It was additionally detected that eyes with PICC tended to show glaucoma-like visual field defects [11]. Recent studies applying swept-source OCT and the enhanced depth imaging mode of spectral-domain OCT demonstrated a posterior deformation of the sclera in regions with PICC [8-10,12]. Although the pathogenesis and clinical significance of PICC has remained unclear, it is important to recognize PICC as a morphologic entity in highly myopic eyes, different from other fundus lesions such as peripapillary choroidal neovascularization or amelanotic choroidal tumors.…”

Section: Introductionmentioning

confidence: 99%

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Peripapillary Intrachoroidal Cavitations. The Beijing Eye Study

et al. 2013

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PurposeTo assess prevalence, size and location of peripapillary intrachoroidal cavitations (PICCs) and their associations in a population-based sample. .MethodsThe population-based Beijing Eye Study 2011 included 3468 individuals with a mean age of 64.6±9.8 years (range:50-93 years). A detailed ophthalmic examination included enhanced depth imaging of the choroid by spectral-domain optical coherence tomography and fundus photography. PICCs were defined as triangular thickening of the choroid with the base at the optic disc border and a distance between Bruch´s membrane and sclera of ≥200μm. Parapapillary large choroidal vessels were excluded.ResultsOut of 94 subjects with high myopia (refractive error <-6.0 diopters or axial length >26.5mm in right eyes), OCT images were available for 89 (94.7%) participants. A PICC was detected in 15 out of these 89 highly myopic subjects (prevalence:16.9±4.0%) and in none of hyperopic, emmetropic or medium myopic subgroups each consisting of 100 randomly selected subjects. Mean PICC width was 4.2±2.3 hours (30°) of disc circumference and mean length was 1363±384μm. PICCs were located most frequently (40%) at the inferior disc border. On fundus photos, a typical yellow-orange lesion was found in 8 (53%) eyes with PICCs. In binary regression analysis, presence of PICCs was significantly associated with optic disc tilting (P=0.04) and presence of posterior staphylomata (P=0.046). ConclusionsPrevalence of PICCs in the adult Chinese population was 16.9±4.0% in the highly myopic group, with no PICCs detected in non-highly myopic eyes. PICCs were located most frequently at the inferior optic disc border. Only half of the PICCs detected on OCT images showed a yellow-orange lesion on fundus photos. Presence of PICC was significantly associated only with an increased optic disc tilting and presence of posterior staphylomata, while it was not associated with axial length, refractive error or other ocular or systemic parameters.

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Section: Discussioncontrasting

confidence: 58%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Peripapillary Intrachoroidal Cavitations. The Beijing Eye Study

et al. 2013

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“…In previous 2 studies however, 10 out of 13 (77%) patients and 44 out of 83 (53%) of patients with PICCs had a unilateral lesion, so that patients with unilateral PICC may represent a major subgroup of patients with PICCs. 8,9 The advantage of including only patients with unilateral PICCs into our study was the possibility to compare the eyes with PICCs with their contralateral fellow eyes without PICCs. This intereye intraindividual comparison allowed the analysis of associations without the potential influence of systemic factors, such as age, gender, or systemic diseases.…”

Section: Discussionmentioning

confidence: 99%

“…[1][2][3][4][5][6][7][8][9] It is usually accompanied by a posterior deformation of the sclera in the region of the PICC and occasionally by glaucomalike visual field defects. [7][8][9][10][11] Initially named "peripapillary detachment in pathologic myopia," a PICC was described by Freund et al 12 …”

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confidence: 99%