Characteristics of Scientific Evidence Informing Changed U.S. Preventive Services Task Force Insufficient Evidence Statements

Klabunde, Carrie N.; Ellis, Erin M.; Villani, Jennifer; Neilson, Elizabeth A.; Schwartz, Kat; Vogt, Elizabeth A.; Ngo‐Metzger, Quyen

doi:10.1016/j.amepre.2021.07.014

Cited by 2 publications

(3 citation statements)

References 18 publications

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“…Research indicates that contracts and other directive funding mechanisms have been successfully used to support important and influential studies with the methodological rigor desired for USPSTF evidence syntheses. 2 NIH, PCORI, and other funders should use such mechanisms to ensure that research is conducted promptly in response to research agendas developed by the USPSTF. Funding opportunity announcements should link explicitly to the research agenda from the USPSTF website.…”

Section: Fostering Research In Clinical Preventionmentioning

confidence: 99%

“…An evaluation by ODP of 11 USPSTF "insufficient evidence statements" that were changed between 2010 and 2019 found that a mean of 8.4 years elapsed between release of an I statement for a topic and the issuance of a definitive recommendation with transition to a letter grade. 2 Leaders at both AHRQ and ODP have suggested that research to address key evidence gaps in clinical prevention could be facilitated by clearer articulation and prioritization of these gaps. 3,4 A new report 5 from the National Academies of Sciences, Engineering, and Medicine (National Academies) provides a taxonomy of evidence gaps, as well as recommendations for AHRQ, NIH, and other clinical prevention proponents, in their ongoing efforts to close evidence gaps in clinical prevention research.…”

mentioning

confidence: 99%

“…Although evidence gaps exist for all topics regardless of grade or I statement, they are a particular problem for topics with I statements. An evaluation by ODP of 11 USPSTF “insufficient evidence statements” that were changed between 2010 and 2019 found that a mean of 8.4 years elapsed between release of an I statement for a topic and the issuance of a definitive recommendation with transition to a letter grade . Leaders at both AHRQ and ODP have suggested that research to address key evidence gaps in clinical prevention could be facilitated by clearer articulation and prioritization of these gaps…”

mentioning

confidence: 99%

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Closing Evidence Gaps in Clinical Prevention

Lieu

Wojtowicz

Stratton

2022

JAMA

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Section: Fostering Research In Clinical Preventionmentioning

confidence: 99%

mentioning

confidence: 99%

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confidence: 99%

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Closing Evidence Gaps in Clinical Prevention

Lieu

Wojtowicz

Stratton

2022

JAMA

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Assessing National Institutes of Health Prevention Research on Leading Causes of Death Focused on Racial or Ethnic Minority Populations, Fiscal Years 2016-2020

Ganoza

Alvidrez

Liggins

2023

Ethnicity and Disease

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Objective To characterize the National Institutes of Health (NIH) prevention research portfolio on leading causes of death focused on racial or ethnic minority populations. Research Design Longitudinal analysis of NIH-funded prevention research projects from FY2016-FY2020. Measures Project characteristics including type of prevention, study design, budget, minority health focus, and causes of death addressed. Results Minority health projects comprised 27.0% of prevention projects and 33.1% of funding across all leading causes of death. Homicide (42.9%), diabetes (36.3%), and stroke (35.5%) had the highest proportion of minority health projects and suicide (20.2%), Alzheimer disease (18.8%), and pneumonia or influenza (8.3%) the lowest. Most minority health projects focused on identifying risk factors or on primary prevention efforts (80.3%). Most projects had an observational design (80.0%), and this predominance was observed for each cause of death. There was a significant correlation between the proportion of minority health projects for cause of death and the ratio of minorities versus non-minorities mortality rate. Conclusions Only about one-fourth of NIH-funded prevention research on leading causes of death focused on racial or ethnic minorities, who currently comprise about 40% of the US population. Only a small fraction of minority health prevention projects included an intervention design, suggesting a limited contribution to the evidence base on effective interventions to address racial or ethnic mortality disparities. Also, we identified that the number of projects increase where mortality rate disparities are higher. This portfolio analysis provides a useful baseline to assess future progress in building the minority health prevention research portfolio, a critical component to promoting health equity in population health.

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Characteristics of Scientific Evidence Informing Changed U.S. Preventive Services Task Force Insufficient Evidence Statements

Cited by 2 publications

References 18 publications

Closing Evidence Gaps in Clinical Prevention

Closing Evidence Gaps in Clinical Prevention

Assessing National Institutes of Health Prevention Research on Leading Causes of Death Focused on Racial or Ethnic Minority Populations, Fiscal Years 2016-2020

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