Characteristics of the Optic Nerve Head in Myopic Eyes Using Swept-Source Optical Coherence Tomography

Cheng, Dan; Ruan, Kaiming; Wu, Minhui; Qiao, Yilin; Gao, Weiqian; Lian, Hengli; Shen, Meixiao; Bao, Fangjun; Yang, Yu-Jun; Zhu, Jun; Huang, Haiying; Meng, Xianwei; Shen, Lijun; Ye, Yufeng

doi:10.1167/iovs.63.6.20

Cited by 22 publications

(10 citation statements)

References 42 publications

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“…At the last visit, no significant elevations were found in the IOP; the mean RNFL thickness was slightly higher than the preoperative value. Cheng et al [ 40 ] studied patients aged 18 to 40 years and found that patients with myopia with axial length >26 mm had thicker mean and temporal RNFL than those with axial length <26 mm (119 ± 17.4 μ m, 97.75 ± 30.36 μ m vs. 105.85 ± 12.83 μ m, 67.70 ± 9.61 μ m). However, this change requires further investigation.…”

Section: Discussionmentioning

confidence: 99%

Clinical Observation of Posterior-Chamber Phakic Implantable Collamer Lens V4c Implantation in Myopic Patients with Shallow Anterior Chamber Depth: A Retrospective, Consecutive Observational Study

Yuan,

Wu,

et al. 2024

Journal of Ophthalmology

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Purpose. The reference range for the preoperative anterior chamber angle width for ICL surgery is unclear. Our objective was to assess the clinical effect and the range of anterior chamber angle width of posterior-chamber implantable collamer lens V4c (ICL V4c) implantation in patients with anterior chamber depth (ACD) < 2.8 mm. Methods. Patients who underwent ICL V4c implantation with shallow ACD were included in this retrospective study. The patients’ uncorrected and corrected distance visual acuity, angle of trabecular-iris (TIA), angle-opening distance (AOD500), trabecular-iris space area (TISA500), corneal endothelial cell density, vault, retinal nerve fiber layer thickness, intraocular pressure, visual field, and complications were analyzed. Results. Forty-one patients (68 eyes) completed at least 12 months of follow-up (median follow-up, 30 months). The effectiveness and safety indices were 1.09 ± 0.13 and 1.04 ± 0.21, respectively. The preoperative TIA values on the nasal and temporal sides were 39.78 ± 7.68 degree (range, 25.8-65.1 degree) and 41.54 ± 8.03 degree (range, 28.5-63.00 degree). Forty-seven eyes had uncorrected distance visual acuity ≥1.0, and 55 had corrected distance visual acuity ≥1.0 at the last follow-up visit. The TIA, AOD500, and TISA500 on the nasal and temporal sides were significantly reduced compared to those before surgery (all P<0.01); no eye had an angle closure or elevated intraocular pressure. The ICL V4c vault was 290.88 ± 153.36 μm (range, 60.0-880.0 μm). No severe complications occurred in any patient. Conclusions. In patients with myopia with shallow ACD (2.55-2.79 mm), a preoperative TIA >25.8° is safe and effective for a relatively long time after surgery; however, an extended long-term close follow-up is needed.

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Section: Discussionmentioning

confidence: 99%

Clinical Observation of Posterior-Chamber Phakic Implantable Collamer Lens V4c Implantation in Myopic Patients with Shallow Anterior Chamber Depth: A Retrospective, Consecutive Observational Study

Yuan,

Wu,

et al. 2024

Journal of Ophthalmology

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“…The RNFL thickness has been reported to have decreased by 7 microns for every 1 mm of axial length, and 3 microns for every 1 Diopter sphere [8]. Moreover, the expansion of left γ-zone PPA might be signi cantly correlated with deepened myopic degree [9].…”

Section: Discussionmentioning

confidence: 99%

Bilateral RNFL thickness reduction in a 9 year old myopic boy suffering from unilateral optic neuritis

Fang

Yao

Wang

et al. 2023

Preprint

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The loss of the retinal nerve fiber layer (RNFL) could be caused by myopia and optic neuritis. We described a 9-year-old boy with optic neuritis in the right eye, pseudopapilledema in the left eye, and moderate myopia in both eyes. His best-corrected visual acuity (BCVA) was no light perception (NLP) in the right eye and 1.0 (logarithmic visual acuity chart) in the left eye. On steroid pulse therapy, vison of his right eye recovered. The RNFL thickness of both eyes and average macular ganglion cell (mGCL) thickness of the left eye was reduced in a 16-month follow-up. We speculated that apart from the myopic influence, optic neuritis might directly affect the RNFL thickness in the right eye and indirectly influence the RNFL and mGCL thickness in the left eye due to contralateral effect.

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“…The RNFL thickness has been reported to have decreased by 7 microns for every 1 mm of axial length, and 3 microns for every 1 Diopter sphere[ 8 ]. Moreover, the expansion of left γ-zone PPA might be significantly correlated with deepened myopic degree[ 9 ].…”

Section: Discussionmentioning

confidence: 99%

Bilateral retinal nerve fiber layer thickness reduction in a 9-year-old myopic boy suffering from unilateral optic neuritis: A case report

Zhao,

Yao,

Wang

et al. 2023

World J Clin Cases

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β cells are the main cells responsible for the hypoglycemic function of pancreatic islets, and the insulin secreted by these cells is the only hormone that lowers blood glucose levels in the human body. β cells are regulated by various factors, among which neurotransmitters make an important contribution. This paper discusses the effects of neurotransmitters secreted by various sympathetic and parasympathetic nerves on β cells and summarizes the mechanisms by which various neurotransmitters regulate insulin secretion. Many neurotransmitters do not have a single source and are not only released from nerve terminals but also synthesized by β cells themselves, allowing them to synergistically regulate insulin secretion. Almost all of these neurotransmitters depend on the presence of glucose to function, and their actions are mostly related to the Ca2+ and cAMP concentrations. Although neurotransmitters have been extensively studied, many of their mechanisms remain unclear and require further exploration by researchers.

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Characteristics of the Optic Nerve Head in Myopic Eyes Using Swept-Source Optical Coherence Tomography

Cited by 22 publications

References 42 publications

Clinical Observation of Posterior-Chamber Phakic Implantable Collamer Lens V4c Implantation in Myopic Patients with Shallow Anterior Chamber Depth: A Retrospective, Consecutive Observational Study

Clinical Observation of Posterior-Chamber Phakic Implantable Collamer Lens V4c Implantation in Myopic Patients with Shallow Anterior Chamber Depth: A Retrospective, Consecutive Observational Study

Bilateral RNFL thickness reduction in a 9 year old myopic boy suffering from unilateral optic neuritis

Bilateral retinal nerve fiber layer thickness reduction in a 9-year-old myopic boy suffering from unilateral optic neuritis: A case report

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