Characteristics of traditional Chinese medicine use in patients with rheumatoid arthritis in Taiwan: A nationwide population-based study

Huang, Mingcheng; Pai, Fu-Tzu; Lin, Chun‐Pin; Chang, Ching-Ter; Chang, Hen‐Hong; Lee, Yu‐Chen; Sun, Mao-Feng; Yen, Hung-Rong

doi:10.1016/j.jep.2015.10.024

Cited by 58 publications

(46 citation statements)

References 50 publications

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“…This study also revealed that Dang‐gui‐nian‐tong‐tang (DGNTT) was the most frequently used Chinese herbal formula for the treatment of rheumatic disorders, a finding consistent with earlier research . Furthermore, we discovered a positive therapeutic effect of DGNTT on subsequent incidence of depression.…”

Section: Discussionsupporting

confidence: 90%

Association between use of Chinese herbal medicine and depression risk in patients with rheumatoid arthritis: A nationwide retrospective cohort study

Livneh

Yeh

et al. 2019

Int J of Rheum Dis

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Aim: Depression is a common mental disorder in rheumatoid arthritis (RA) patients and may provoke the onset of poor clinical prognoses. In view of this, whether or not the use of Chinese herbal medicines (CHMs) can alleviate the risk of depression still remains unclear. We conducted a longitudinal cohort study to evaluate the association between CHMs us and depression risk among RA patients. Method:Using claims data from the National Health Insurance of Taiwan, we identified 6609 newly diagnosed RA patients aged 20 years or older between 1998 and 2010. From this sample, we recruited 3386 CHM users and randomly selected 3223 controls using propensity scores matching from the remaining cases as the non-CHMs users. They were followed until the end of 2012 to record depression incidence. A Cox proportional hazards regression model was used to compute the hazard ratio (HR) of depression with regard to the use of CHMs. Results:During the 15-year follow-up, 249 CHM users and 314 non-CHM users developed depression, representing an incidence rate of 9.33 and 14.98, respectively, per 1000 person-years. We found that use of CHMs was associated with lower risk of depression by 38% (95% confidence interval 0.54-0.76). The most predominant effect was observed in those receiving CHMs for over 2 years (adjusted HR 0.34).Seven commonly prescribed CHMs could lessen the risk of depression: Chuan-niu-xi, | 987 LI et aL.

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Section: Discussionsupporting

confidence: 90%

Association between use of Chinese herbal medicine and depression risk in patients with rheumatoid arthritis: A nationwide retrospective cohort study

Livneh

Yeh

et al. 2019

Int J of Rheum Dis

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“…We used a network analysis open-sourced freeware NodeXL (http://nodexl.codeplex.com/) to determine the core pattern of Chinese herbal medicine prescribed for DUB patients. As described in our previous reports [14], the thicker the line was, the more interrelated were the Chinese herbal formulas and the co-prescribed Chinese herbal formulas.…”

Section: Methodsmentioning

confidence: 83%

The utilization of traditional Chinese medicine in patients with dysfunctional uterine bleeding in Taiwan: a nationwide population-based study

Lin

Chiang

et al. 2017

BMC Complement Altern Med

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BackgroundMany patients with gynecological disorders seek traditional medicine consultations in Asian countries. This study intended to investigate the utilization of traditional Chinese medicine (TCM) in patients with dysfunctional uterine bleeding (DUB) in Taiwan.MethodsWe analyzed a cohort of one million individuals randomly selected from the National Health Insurance Research Database in Taiwan. We included 46,337 subjects with newly diagnosed DUB (ICD-9-CM codes 626.8) from January 1, 1997 to December 31, 2010. The patients were categorized into TCM seekers and non-TCM seekers according to their use of TCM.ResultsAmong the subjects, 41,558 (89.69%) were TCM seekers and 4,779 (10.31%) were non-TCM seekers. Patients who were younger tended to be TCM seekers. Most of the patients had also taken Western medicine, especially tranexamic acid and non-steroidal anti-inflammatory drugs (NSAIDs). More than half of TCM seekers (55.41%) received combined treatment with both Chinese herbal remedies and acupuncture. The most commonly used TCM formula and single herb were Jia-Wei-Xiao-Yao-San (Bupleurum and Peony Formula) and Yi-Mu-Cao (Herba Leonuri), respectively. The core pattern of Chinese herbal medicine for DUB patients consisted of Jia-Wei-Xiao-Yao-San, Xiang-Fu (Rhizoma Cyperi), and Yi-Mu-Cao (Herba Leonuri).ConclusionsTCM use is popular among patients with DUB in Taiwan. Further pharmacological investigations and clinical trials are required to validate the efficacy and safety of these items.

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“…In our study, TCM users had a higher frequency of using donepezil and rivastigmine than non‐TCM users. The interval between an AD diagnosis and the first TCM consultation was shorter than in previous studies of chronic diseases, such as rheumatoid arthritis . One of the possibilities is that patients used WM initially and then sought a TCM consultation when they were unsatisfied with conventional therapy .…”

Section: Discussionmentioning

confidence: 90%

Utilization of Western medicine and traditional Chinese medicine among patients with Alzheimer's disease in Taiwan: a nationwide population‐based study

Lai

Chiang

et al. 2017

Euro J of Neurology

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Characteristics of traditional Chinese medicine use in patients with rheumatoid arthritis in Taiwan: A nationwide population-based study

Cited by 58 publications

References 50 publications

Association between use of Chinese herbal medicine and depression risk in patients with rheumatoid arthritis: A nationwide retrospective cohort study

Association between use of Chinese herbal medicine and depression risk in patients with rheumatoid arthritis: A nationwide retrospective cohort study

The utilization of traditional Chinese medicine in patients with dysfunctional uterine bleeding in Taiwan: a nationwide population-based study

Utilization of Western medicine and traditional Chinese medicine among patients with Alzheimer's disease in Taiwan: a nationwide population‐based study

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