This paper established a lateral stiffness coupling model to investigate the lateral characteristics of air spring system under crosswind conditions. The nonlinear super-elastic characteristics, coupling characteristics of the air spring, lateral stiffness characteristics of emergency spring, and damping force are studied. The accuracy of the lateral stiffness model is validated by comparing with experimental data. In addition, the impact of geometric parameters on the lateral stiffness characteristics is discussed by a sensitivity analysis method, as well as the effect of the lateral stiffness model on vehicle mechanical performance is analyzed. The conclusions show that the lateral stiffness model can well predict the lateral characteristics of the air spring system, and provide theoretical guidance for the parameter design of rail vehicles and vehicle ride comfort improvement.