Characterization and degradation behavior of AZ31 alloy surface modified by bone-like hydroxyapatite for implant applications

Wen, Cuilian; Guan, Shaokang; Li, Peng; Ren, Chao; Wang, Xiang; Hu, Zhonghua

doi:10.1016/j.apsusc.2008.09.078

Cited by 293 publications

(140 citation statements)

References 30 publications

Supporting

Mentioning

136

Contrasting

Order By: Relevance

“…Therefore, one of the promising options to surface modify magnesium scaffolds is using electrochemical deposition which includes low deposition temperature and is capable of creating uniform coatings with controlled thickness and chemical composition [56][57][58].…”

Section: Biomedical Coatings On Magnesium Scaffoldsmentioning

confidence: 99%

See 1 more Smart Citation

Porous magnesium-based scaffolds for tissue engineering

Yazdimamaghani

Razavi

Vashaee

et al. 2017

Materials Science and Engineering: C

241

115

View full text Add to dashboard Cite

Section: Biomedical Coatings On Magnesium Scaffoldsmentioning

confidence: 99%

“…Healing process of bone defects can be accelerated by loose hydroxyapatite coating which allows easier infiltration and ingrowth of new bone tissue. [57][58][59].…”

Section: Biomedical Coatings On Magnesium Scaffoldsmentioning

confidence: 99%

Porous magnesium-based scaffolds for tissue engineering

Yazdimamaghani

Razavi

Vashaee

et al. 2017

Materials Science and Engineering: C

241

115

View full text Add to dashboard Cite

“…Osteoconduction is thus the process by which bone is directed to conform to the surface of a given material 1) . Therefore, hydroxyapatite is widely used in bone reconstruction [17][18][19][20] . However, hydroxyapatite has a critical disadvantage for use in dental implants because of its low modulus of elasticity and low fracture toughness 21) .…”

Section: Introductionmentioning

confidence: 99%

Osteoblast compatibility of materials depends on serum protein absorbability in osteogenesis

et al. 2012

View full text Add to dashboard Cite

Titanium has an osseointegrative property, while hydroxyapatite has an osteoconductive property. It remains a matter of controversy among researchers whether hydroxyapatite has higher osteoblast compatibility than titanium. Here, we compared the activities between osteoblasts cultured on titanium and those cultured on hydroxyapatite. An osteoblast-like cell line, MC3T3-E1, was cultured on machined titanium, evaporated titanium, and hydroxyapatite disks to compare the affi nity of osteoblasts to each of these materials. The adhesion and proliferation of MC3T3-E1 cells were higher on hydroxyapatite disks than on the other disks. Osteoblast differentiation was not affected by the nature of disks investigated, but calcium was more easily deposited on the hydroxyapatite disks. The amount of absorbed serum proteins detected on hydroxyapatite was greater than that on titanium. In conclusion, our results indicate hydroxyapatite is a more suitable material for osteoblast growth than titanium because of its higher absorption of serum proteins.

show abstract

“…Several techniques have been used to deposit calciu m phosphate coatings onto Mg substrates, these range fro m anodization [183], b io-mimet ic co atings [1 84-18 6], ele ctro-deposition [1 87, 18 8], hydrothermal [189] and wet chemical methods [190,191].…”

Section: Calciu M Phosphate Surface Coatingsmentioning

confidence: 99%

Biomedical Magnesium Alloys: A Review of Material Properties, Surface Modifications and Potential as a Biodegradable Orthopaedic Implant

Poinern¹,

Brundavanam²,

Fawcett³

2013

AJBE

283

View full text Add to dashboard Cite

Magnesium and magnesium based alloys are lightweight metallic materials that are extremely biocompatib le and have similar mechanical properties to natural bone. These materials have the potential to function as an osteoconductive and biodegradable substitute in load bearing applicat ions in the field of hard t issue engineering. However, the effects of corrosion and degradation in the physiological environ ment of the body has prevented their wide spread applicat ion to date. The aim o f this review is to examine the properties, chemical stability, degradation in situ and methods of improving the corrosion resistance of magnesium and its alloys for potential application in the orthopaedic field. To be an effective imp lant, the surface and sub-surface properties of the material needs to be carefully selected so that the degradation kinetics of the implant can be efficiently controlled. Several surface modification techniques are presented and their effectiveness in reducing the corrosion rate and methods of controlling the degradation period are discussed. Ideally, balancing the gradual loss of material and mechanical strength during degradation, with the increasing strength and stability of the newly forming bone tissue is the ultimate goal. If this goal can be achieved, then orthopaedic implants manufactured fro m magnesium based alloys have the potential to deliver successful clinical outcomes without the need for revision surgery.

show abstract

Characterization and degradation behavior of AZ31 alloy surface modified by bone-like hydroxyapatite for implant applications

Cited by 293 publications

References 30 publications

Porous magnesium-based scaffolds for tissue engineering

Porous magnesium-based scaffolds for tissue engineering

Osteoblast compatibility of materials depends on serum protein absorbability in osteogenesis

Biomedical Magnesium Alloys: A Review of Material Properties, Surface Modifications and Potential as a Biodegradable Orthopaedic Implant

Contact Info

Product

Resources

About